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Application of traditional Chinese medicine composition in relief of asthenopia and prevention, delay and treatment of myopia and complications thereof

A technology for relieving visual fatigue and a composition, which can be used in drug combinations, medical preparations containing active ingredients, and medical raw materials derived from mollusks, etc., and can solve the problem of lack of theoretical guidance and research on myopia.

Active Publication Date: 2015-07-15
BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent document CN103768283A once disclosed a kind of traditional Chinese medicine for treating various eye diseases, which included saffron in different proportions, fruit of medlar, fruit of sand garden, fruit of ligustrum lucidum, fruit of plantain, fruit of Schisandra, fruit of green scorpion, seed of cassia, honeysuckle, jasmine, It is made of 27 Chinese herbal medicines such as white chrysanthemum, stone flower, and dense Mongolian flower. In addition, Chinese patent document CN1168277A also discloses a vision granule, which is composed of raw rehmannia, rehmannia glutinosa, medlar, chrysanthemum, poria cocos, plantain seed, schisandra, It is made of 14 traditional Chinese medicinal materials such as Radix Changshen and Phellodendron Phellodendri. The traditional Chinese medicine formula provided by the above-mentioned patent documents is composed of traditional Chinese medicine ingredients such as nourishing blood and promoting blood circulation, nourishing liver and kidney, clearing liver and improving eyesight, and can be used for outer eye and inner eye on the basis of syndrome differentiation. There are many miscellaneous diseases in ophthalmology, and there is no specific theoretical guidance and research for myopia

Method used

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  • Application of traditional Chinese medicine composition in relief of asthenopia and prevention, delay and treatment of myopia and complications thereof
  • Application of traditional Chinese medicine composition in relief of asthenopia and prevention, delay and treatment of myopia and complications thereof

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Effect test

Embodiment 1

[0022] The raw material formula of the traditional Chinese medicine composition of this embodiment is as follows, Codonopsis 25g, Huaijiao 10g, Phellodendron cortex 8g, Shayuanzi 6g, pearl powder 3g, amber powder 3g and Chuan Fritillaria 6g.

[0023] The raw materials of the above formula are mixed, crushed and passed through a sieve of 80-100 meshes to obtain a fine powder of the raw materials, and the above-mentioned fine powder is packed into a commercially available capsule shell to form capsules, wherein each capsule contains 0.5 g of the fine powder.

Embodiment 2

[0025] The raw material formula of the traditional Chinese medicine composition of the present embodiment is as follows, Codonopsis 20g, Huaijiao 10g, Phellodendron Phellodendri 10g, Shayuanzi 10g and pearl powder 1.5g.

[0026] Mix the above-mentioned raw materials, crush them, decoct them with water 20 times the weight of the materials, decoct and extract twice, and extract for 2 hours each time, then collect and combine the extracts, and concentrate the extracts to a relative Extraction with a density of 1.15, dilute it with water 7 times the volume of the extract, and filter to obtain a clarified extract; pass the clarified extract into large pores with a flow rate of 10 times the bed volume / hour for adsorption, washing, and analysis The adsorption resin column is first washed with water, then washed with 20% ethanol, and finally analyzed with 50% ethanol; the ethanol is recovered from the analysis solution until it has no alcohol smell, concentrated, and spray-dried to obt...

Embodiment 3

[0028] The raw material formula of the traditional Chinese medicine composition of the present embodiment is as follows, Codonopsis 25g, Huaijiao 10g, Phellodendron 10g, Shayuanzi 10g, Pearl powder 1.5g, Amber powder 1.5g and Chuan Fritillaria 6g.

[0029] Mix the raw materials of the above formula, and after preliminary crushing, make 1-10 μm ultrafine powder through ultrafine pulverization technology, and mix the above ultrafine powder with normal saline to form a suspension to prepare an aqueous solution, wherein every 5ml of normal saline Mix 1.0g of superfine powder in it.

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Abstract

The invention discloses application of a traditional Chinese medicine composition in relief of asthenopia and prevention, delay and treatment of myopia and complications thereof. The traditional Chinese medicine composition comprises the following active pharmaceutical ingredients: 10-30 parts by weight of pilose asiabell root, 3-10 parts by weight of pagodatree pods, 3-15 parts by weight of amur corktree bark, 5-15 parts by weight of flastem milkvetch seeds and 1-3 parts by weight of pearl essence; the traditional Chinese medicine composition preferably further comprises 1-3 parts by weight of amber powder and 6-15 parts by weight of unibract fritillary bulb, wherein pilose asiabell root and flastem milkvetch seeds have the effects of benefiting yang, invigorating spleen and improving eyesight, have the function of increasing retinal photoreceptor cells and are taken as monarch drugs, pagodatree pods and amur corktree bark have the effects of clearing liver, improving eyesight, being bitter and cold and strengthening yin, can clear deficiency-heat of a retinal pigment cell layer and are taken as minister drugs, pearl essence has the effects of calming nerves, consolidating body resistance and reinforcing toughness of a sclera tissue and is taken as an assistant drug, the above drugs form a prescription by taking 'benefiting yang and strengthening yin' as treatment principles, and the traditional Chinese medicine composition has the advantages of simple drug taste, mild drug property, mutual coordination and synergy, and can clear deficiency-heat, solidify eyeball tissues, inhibit sclera deformation and reinforce retinal pigment cells, and further prevent, delay and control the development of myopia.

Description

technical field [0001] The invention relates to an application of a traditional Chinese medicine composition, in particular to an application of a traditional Chinese medicine composition in relieving visual fatigue and preventing, delaying and treating myopia and its complications, and belongs to the field of traditional Chinese medicine preparations. Background technique [0002] Human beings have entered the era of information and networking, physical activity is decreasing, and mental workload is increasing. The era has changed people's lifestyles, and the visual system has to receive more information (90% of external information is received through the eyes. ), the eye is the most sensitive organ of the body, and it is also the most fatigued organ at present. In order to meet the long-term close reading and fine operation, the human eye needs to carry out long-term adaptive adjustment when working at close range, resulting in myopia in the crowd The incidence rate of th...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P27/10A61K35/618
Inventor 马东丽
Owner BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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