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Corrosion-proof composition and application of corrosion-proof composition in cosmetics

A composition and cosmetic technology, applied in the direction of cosmetics, cosmetic preparations, chemicals for biological control, etc., can solve problems affecting skin color, dark yellow, pigmentation, etc., and achieve the effect of low risk to human health

Active Publication Date: 2015-08-26
GUANGZHOU KENENG COSMETICS RES CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Although natural products with antibacterial function have been applied to a variety of products with high safety requirements such as food, health care products, etc., the application in cosmetics is relatively seldom, the main reasons are: first, with Food and health care products are different from products that are directly ingested for gastrointestinal digestion and absorption. Cosmetics apply products directly on the skin and absorb them through the skin. The pigments and pigment enzymes contained in them may affect the skin color and cause dark spots. Adverse effects such as yellowing, pigmentation, and depigmentation; second, some antibacterial natural products may cause skin allergies, which is one of the reasons for limiting their use

Method used

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  • Corrosion-proof composition and application of corrosion-proof composition in cosmetics
  • Corrosion-proof composition and application of corrosion-proof composition in cosmetics
  • Corrosion-proof composition and application of corrosion-proof composition in cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1 composition bacteriostasis experiment

[0039] 1. Materials

[0040] 1.1 Test material

[0041] Clove extract, Ginkgo biloba extract and Coptis chinensis extract were obtained by the following methods in our laboratory.

[0042] Clove extract: the extract obtained by water or water-ethanol extraction with the plant spice lilac as raw material. Grind the dried Chinese medicinal material of cloves through a 100-mesh sieve, use 85% ethanol as the extraction solvent according to the ratio of 15mL extraction solvent per gram of cloves, extract at 85°C for 2 hours, centrifuge, filter, collect the filtrate, and record it as the first filtrate ; filter residue according to the ratio of 10mL extraction solvent per gram of filter residue, use 70% ethanol as the extraction solvent, extract at 80°C for 3 hours, centrifuge, filter, collect the filtrate, and record it as the second filtrate; combine the first filtrate and the second The filtrate was concentrated by ro...

Embodiment 2

[0078] Embodiment 2 cosmetics add test

[0079] 2.1 Mix clove extract, ginkgo extract, Coptis chinensis extract and sorbitan octanoate directly in a volume ratio of 2:1:2:1, and prepare concentrations of 0.8mg / mL and 2mg / mL respectively , 0.6mg / mL clove extract, ginkgo extract and coptis extract (based on the content of eugenol, ginkgo flavonoids and berberine) and the composition of 15% (w / w) sorbitan caprylate solution. Add to cosmetics according to 1%~5% (w / w), preferably 2.5%~5%, the formula is shown in Table 4 or Table 5:

[0080] Table 4. O / W emulsified cosmetic cream (sample 1) formula

[0081] raw material name

Addition amount (mass ratio)

A: cetearyl alcohol

2

monoglyceride

1

stearic acid

3

White oil (26#)

6

Isopropyl Myristate IPM

4

antiseptic composition

2

Span-60

1

B: EDTA-2Na

0.05

Glycerin

5

Tween-60

2

1% sodium hyaluronate

3

...

Embodiment 3

[0095] Embodiment 3 skin irritation experiment

[0096] 3.1 Human skin patch test of different concentration compositions

[0097] The human patch test examines the possibility of the test substance causing adverse reactions on the human skin. Refer to the standards of GB17149.1-1997 "Diagnostic Criteria and Treatment Principles of Cosmetic Skin Diseases", GB17149.2-1997 "Diagnostic Criteria and Treatment Principles of Cosmetic Contact Dermatitis" and "2007 Hygienic Standards for Cosmetics", according to the selection criteria of the subjects Choose to participate in the experiment 30 people, aged 22-35 years old.

[0098] A total of 17 samples of each single component solution of different concentrations in Example 1.5.1 and the composition in Example 2 were used as test substances, and the amount of about 250 μL was put into the spot test device, and the control well was a blank control (no substance was placed). Apply the spot test device with the test substance on the cu...

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Abstract

The invention discloses a corrosion-proof composition which comprises a combination of two or more of a clove extract, a gingko extract, a coptis root extract and sorbitan octoate. The composition has an inhibiting and killing effect on various bacteria and fungi. The composition cannot cause the problems such as skin allergy or pigment sediment, and skin yellowing, so that the composition is applicable to cosmetics. The invention discloses a cosmetic comprising the corrosion-proof composition at the same time.

Description

technical field [0001] The invention belongs to the field of natural products / cosmetics, and relates to a composition with antiseptic / antibacterial effects. Background technique [0002] Because cosmetics contain a variety of nutrients, they are extremely susceptible to microbial contamination during production, storage and use, which in turn leads to product deterioration such as turbidity, precipitation, color change, foaming, and odor. Once the product deteriorates, some efficacy components Components may be decomposed into substances that are irritating to human skin, making the commercial value of the product lose. If cosmetics are contaminated by pathogenic bacteria, such pathogenic microorganisms and their metabolites will affect human health. Therefore, it is of great significance to add an appropriate amount of preservatives, which can effectively prevent the product from being polluted and multiplied by microorganisms, and ensure the safety and hygienic quality of...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q19/00A01N65/32A01P1/00
Inventor 张金金刘德海刘培黄梓萍丛琳毛勇进高红军张伟杰张楚标
Owner GUANGZHOU KENENG COSMETICS RES CO LTD
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