Corrosion-proof composition and application of corrosion-proof composition in cosmetics
A composition and cosmetic technology, applied in the direction of cosmetics, cosmetic preparations, chemicals for biological control, etc., can solve problems affecting skin color, dark yellow, pigmentation, etc., and achieve the effect of low risk to human health
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[0038] Example 1 Composition Antibacterial Experiment
[0039] 1. Material
[0040] 1.1 Test materials
[0041] Clove extract, Ginkgo biloba extract and Coptis extract were all extracted by our laboratory according to the following methods.
[0042] Clove extract: Take plant spice lilac flower as raw material and extract with water or water-ethanol. Crush the dried Chinese medicinal materials of cloves through a 100-mesh sieve, and use 85% ethanol as the extraction solvent according to the ratio of 15mL extraction solvent per gram of cloves. Incubate at 85°C for 2h, centrifuge and filter, and collect the filtrate, which is recorded as the first filtrate ; The filter residue is based on the ratio of 10mL extraction solvent per gram of filter residue, using 70% ethanol as the extraction solvent, incubating at 80°C for 3 hours, centrifuging, filtering, collecting the filtrate, and recording it as the second filtrate; combining the first filtrate and the second filtrate The filtrate was...
Example Embodiment
[0078] Example 2 Cosmetic Addition Test
[0079] 2.1 The four components of clove extract, ginkgo extract, coptis extract and sorbitan caprylate were directly mixed according to the volume ratio of 2:1:2:1, and the concentrations were respectively 0.8mg / mL and 2mg / mL , 0.6mg / mL clove extract, Ginkgo biloba extract and Coptis extract (based on the content of eugenol, ginkgo flavone and berberine) and a 15% (w / w) sorbitan caprylate solution. Add 1% to 5% (w / w) to cosmetics, preferably 2.5% to 5%, the formula is shown in Table 4 or Table 5:
[0080] Table 4. O / W emulsified cosmetic cream (sample 1) formula
[0081] raw material name
[0082] Table 5. O / W emulsified cosmetic emulsion (sample 2) formula
[0083] raw material name
[0084] The method for preparing the cosmetics of the application samples 1 and 2. The raw material composition of the cosmetics includes an oil phase, an aqueous phase and the antiseptic composition of the present invention, and the method includes:
[0...
Example Embodiment
[0095] Example 3 Skin irritation test
[0096] 3.1 Human skin patch test of different concentrations of composition
[0097] The human patch test examines the possibility of the test substance causing adverse reactions to human skin. Refer to GB17149.1-1997 "General Principles of Diagnostic Standards and Treatment Principles for Cosmetic Dermatitis", GB17149.2-1997 "Diagnostic Standards and Principles for Treatment of Cosmetic Contact Dermatitis" and "Hygiene Standards for Cosmetics 2007" standards, according to the criteria for selection of subjects Choose to participate in the trial 30 people, aged 22-35 years old.
[0098] A total of 17 samples of each single component solution of different concentrations in Example 1.5.1 and the composition of Example 2 were used as test substances, and the amount of about 250 μL was put into the spot tester, and the control hole was a blank control (no substance was placed). The patch tester with the test substance was applied to the curved si...
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