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Runing granules and preparation method thereof

A technology of Runing Granules and Bupleurum Radix, which is applied in the field of Runing Granules and its preparation, can solve problems affecting product quality, long medication time, poor patient compliance, etc., to improve bioavailability, increase utilization rate, and improve immunity force effect

Active Publication Date: 2015-08-26
NANJING TONGRENTANG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage is that there are many fine powders of medicinal materials in this product, and the compressibility of the particles prepared by conventional methods is poor, which makes it difficult for the hardness, friability, and weight difference of the tablet to meet the standards, and the surface of the compressed tablet is uneven, which affects the quality of the tablet. product quality
This product has a strong bitter and pungent taste, large dosage, long medication time, large tablet size, difficulty in swallowing, poor patient compliance, and difficult to guarantee drug efficacy

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] 1. Chinese medicine components: Weigh 230g of Bupleurum bupleurum, 150g of angelica, 50g of vinegar cyperus, 60g of salvia miltiorrhiza, 100g of fried white peony root, 70g of Wangbuliuxing, 60g of red peony root, 90g of fried Atractylodes macrocephala, and Poria cocos according to the weight ratio. 50g, green peel 50g, tangerine peel 50g and mint 40g.

[0050] 2. Preparation steps:

[0051] (1) Get Bupleurum radix, Angelica sinensis, Cyperus cyperi, green peel, tangerine peel and peppermint and carry out distillation with a steam distillation device for 6 hours to extract volatile oil;

[0052] (2) clathrate the above-mentioned extracted volatile oil with β-cyclodextrin to make the first granule for later use;

[0053] (3) Remove impurities from the remaining medicinal materials, wash them, put them in an extraction tank, and soak them in 7 times the volume of purified water with a temperature of 20° C. for 40 minutes;

[0054] (4) Combine the medicinal residues afte...

Embodiment 2

[0060] 1. Chinese medicine components: Weigh 200g of Bupleurum bupleurum, 200g of angelica, 150g of vinegar Cyperus, 150g of Salvia miltiorrhiza, 80g of fried white peony root, 80g of Wang Buliuxing, 50g of red peony root, 80g of fried Atractylodes macrocephala, and Poria cocos according to the weight ratio. 40g, green peel 60g, tangerine peel 40g and mint 50g.

[0061] 2. Preparation steps:

[0062] (1) Get Bupleurum radix, Angelica sinensis, Cyperus cyperi, green peel, tangerine peel and peppermint and carry out distillation with a steam distillation device for 7 hours to extract volatile oil;

[0063] (2) clathrate the above-mentioned extracted volatile oil with β-cyclodextrin to make the first granule for later use;

[0064] (3) Remove impurities from the remaining medicinal materials, wash them, put them in an extraction tank, and soak them in 6 times the volume of purified water at a temperature of 20°C for 30 minutes;

[0065] (4) Combine the medicinal residues after ...

Embodiment 3

[0071] 1. Chinese medicine components: Weigh 350g of Bupleurum bupleurum, 100g of angelica, 80g of vinegar Cyperus, 30g of Salvia miltiorrhiza, 120g of fried white peony root, 100g of Wang Buliuxing, 80g of red peony root, 50g of fried Atractylodes macrocephala, and Poria cocos according to the weight ratio. 90g, green peel 80g, tangerine peel 100g and mint 20g.

[0072] 2. Preparation steps:

[0073] (1) Get Bupleurum radix, Angelica sinensis, Cyperus cyperi, green peel, tangerine peel and peppermint and carry out distillation with a steam distillation device for 87 hours to extract volatile oil;

[0074] (2) clathrate the above-mentioned extracted volatile oil with β-cyclodextrin to make the first granule for later use;

[0075] (3) Remove impurities from the remaining medicinal materials, wash them, put them in an extraction tank, and soak them in 8 times the volume of purified water with a temperature of 25° C. for 35 minutes;

[0076] (4) Combine the medicinal residues ...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to Runing granules and a preparation method thereof. The Runing granules comprise the following components in parts by weight: 200-350 parts of Chinese thorowax root, 100-300 parts of Chinese angelica, 30-150 parts of vinegar nutgrass galingale rhizome, 30-150 parts of red-rooted salvia root, 50-150 parts of parched white peony root, 50-100 parts of cowherb seed, 50-100 parts of red paeony root, 50-150 parts of fried large-head atractylodes rhizome, 20-150 parts of poria cocos, 30-80 parts of green tangerine peel, 20-100 parts of tangerine peel and 20-50 parts of mint. The prepared Runing granules are capable of regulating vital energy and dispelling melancholy and are used for treating mammary nodules caused by the stagnation of liver qi, and symptoms include premenstrual breast distending pain, two-rib distending pain and breast qi stagnation.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a Runing granule and a preparation method thereof. Background technique [0002] Mammary gland hyperplasia is mainly the benign hyperplasia of the mammary gland stroma. The hyperplasia can occur around the glandular duct and be accompanied by the formation of cysts of various sizes. . The etiology and pathogenesis of mammary gland hyperplasia are related to endocrine disorders and mental factors. The external environment of human existence, work and living conditions, interpersonal relationships, neuropsychological factors caused by various pressures, etc. can change the internal environment of the human body, thereby Affecting the function of the endocrine system, and then making the secretion of one or several hormones abnormal, the secretion of progesterone is reduced, and the relative increase of estrogen is an important reason for the onset ...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61K9/16A61P15/14
Inventor 浩健周勤文陈家进
Owner NANJING TONGRENTANG PHARM CO LTD
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