Rapid Bacterial Resistance Prediction System and Its Prediction Method

A technology for predicting system and drug resistance, applied in the field of public health and environment, which can solve the problems of isolated measurement data, inconvenient viewing, retrospective data, and inability to establish long-term and effective epidemic files of drug-resistant strains, so as to eliminate differences and reduce costs. speed effect

Active Publication Date: 2017-06-20
杨亮
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] However, the data after each measurement of the traditional bacterial resistance test is only used as a current reference, and it is not easy to view and trace the data, and it is also impossible to establish a long-term and effective epidemic file of drug-resistant strains; and the measurement data is isolated, and the data is usually difficult to be used by different hospitals. share between
[0004] Due to the high mutation rate of bacterial genomes, the characteristics and drug resistance of individual bacterial genomes determined by traditional methods are often very unstable, making it difficult for medical staff to prescribe appropriate antibiotics based on previous experience even for the same bacteria

Method used

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  • Rapid Bacterial Resistance Prediction System and Its Prediction Method
  • Rapid Bacterial Resistance Prediction System and Its Prediction Method
  • Rapid Bacterial Resistance Prediction System and Its Prediction Method

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Embodiment 1

[0045] The present invention will be described in further detail below with reference to the embodiments and the accompanying drawings, but the embodiments of the present invention are not limited thereto.

[0046] like figure 1 As shown, the bacterial drug resistance rapid prediction system of this embodiment includes bacterial genomic DNA extraction equipment, bacterial genomic fingerprint typing equipment, intelligent terminal, cloud server and bacterial database server. Type equipment is connected, and the bacterial genome fingerprint typing equipment is connected through lines (such as USB, serial port UART, bus SPI, I 2 C, etc.) or wireless signals (such as WIFI, Bluetooth, etc.) are connected to the intelligent terminal, and the intelligent terminal is connected to the Internet through the Internet (wired or wireless, such as Ethernet, cable modem, WIFI, Bluetooth, GSM / GPRS, 3G, 4GLTE, etc.) is connected with a cloud server, and the cloud server is encrypted and connecte...

Embodiment 2

[0120] like figure 1 and Figure 5 As shown, the software flow of the bacterial drug resistance rapid prediction system of this embodiment is implemented through the following steps:

[0121] A. The user will obtain a sample of bacterial genomic DNA to be tested in the bacterial genomic DNA extraction equipment;

[0122] B. The user places the DNA sample in the gel electrophoresis module of the bacterial genome fingerprinting equipment to generate a striped fingerprint and the signal is collected by the image collector;

[0123] C. The user places the DNA sample in the DNA microarray module of the bacterial genome fingerprinting equipment to generate a microarray-like fingerprint and the signal is collected by the image collector;

[0124] D. The user sends the DNA collected by the bacterial genome fingerprinting equipment through the line (such as USB, serial port UART, bus SPI, I 2 C, etc.) or wireless signals (such as WIFI, Bluetooth, etc.) are sent to the smart terminal...

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Abstract

The invention discloses a bacterial drug resistance rapid prediction system and a prediction method thereof. The system includes a bacterial genome DNA extraction device, a bacterial genome fingerprint typing device, an intelligent terminal, a cloud server and a bacterial database server. The bacterial genome DNA The extraction device is connected with the bacterial genome fingerprint typing device, and the bacterial genome fingerprint typing device is connected with an intelligent terminal through a line or a wireless signal, and the intelligent terminal is connected with a cloud server through the Internet, and the cloud server is also connected with a bacterial database server . The system and method of the present invention utilize the technology of Internet and safe cloud computing storage, which can be applied not only to the prediction of antibiotic resistance spectrum of clinical isolates, but also to the prediction of antibiotic resistance spectrum of environmental isolates, which is beneficial to guide professionals Proper use of antibiotics can reduce the speed of the spread of drug resistance genes, and can also become an information platform for the bacterial drug resistance surveillance network.

Description

technical field [0001] The invention relates to a bacterial drug resistance prediction system, in particular to a bacterial drug resistance rapid prediction system and a prediction method thereof, belonging to the fields of environment and public health. Background technique [0002] At present, the detection of bacterial resistance is mainly divided into two categories: the first type uses culture technology to cultivate bacteria in solid or liquid medium containing different antibiotics and directly observe the inhibition of bacterial growth by antibiotics, because bacterial culture is easy to have Contamination and generally take 24 hours or more to detect growth, and each antibiotic is added to the medium separately (adding more than two antibiotics at the same time may produce synergistic or antagonistic effects), requiring multiple cultures to determine A strain is resistant to multiple antibiotics, so this traditional method has great limitations; the second type is t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M1/34C12Q1/68
CPCC12Q1/6806C12Q2537/165
Inventor 杨亮陈军
Owner 杨亮
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