178results about How to "Reduce the speed of propagation" patented technology

The invention discloses a gRNA sequence. The sequence in a CRISPR-Cas9 system is capable of editing a DNA sequence by taking a resistance plasmid specific site in bacteria as a target sequence. The gRNA sequence is shown as SEQ ID NO:1 and/or 2. The invention also discloses the CRISPR-Cas9 system of the gRNA sequence and an application of the CRISPR-Cas9 system in preparing a drug for treating resistant bacterial infection. The CRISPR-Cas9 system provided by the invention is capable of targeting two super resistance genes of NDM-1 and MCR-1, simultaneously eliminating the two resistance genes and guaranteeing the use effect of carbapenms and colistin antibiotics.

An inhaler, a store and a method for atomizing a dry medicament formulation are disclosed. The medicament formulation is first dissolved by a liquid solvent and then atomized together with the solvent. This allows easy metering and satisfactory storage of the medicament formulation in the dry state. Particularly preferably, the dry medicament formulation is prepared by drying an initially liquid medicament formulation. Alternatively, the dried medicament formulation may also be expelled in dry form by means of a gas current and atomized.

A dispensing device and a storage device for dispensing a formulation as a spray. The storage device has multiple separate and pre-metered doses of the formulation in receptacles or cavities. In order to allow a very compact arrangement, the receptacles or cavities are arranged in a first group and a second group axially offset, and preferably, forming a double ring arrangement, and the storage device is rotatable and axially moveable for dispensing the doses one after the other.

A method of producing a ticking includes laminating a flame retardant backer to film material, wherein the backer releases flame retardant in the vapor phase that reduces the rate of flame propagation along the film material, when the ticking layer is exposed to flame. The backer is laminated in direct contact with the film material. In some embodiments, the laminated ticking is configured to release less than 15 MJ of heat in the first ten minutes when exposed to a flame in accordance with the testing protocol set forth in 16 CFR 1633. Upholstered articles, such as mattresses, mattress foundations, and articles of furniture, may incorporate the ticking layer.

The invention discloses an MEMS (Micro Electro Mechanical System) infrared sensor based on film bulk acoustic resonator and a preparation method of the MEMS infrared sensor. The MEMS infrared sensor sequentially comprises a metal block, a piezoelectric oscillation pile and an acoustic wave reflection layer, wherein the piezoelectric oscillation pile and the metal block are sequentially deposited on the acoustic wave reflection layer; the piezoelectric oscillation pile comprises a bottom electrode, a piezoelectric layer and an upper electrode which are sequentially deposited on the acoustic wave reflection layer; the upper electrode is arranged on the surface of the infrared sensor and called as an infrared window film; the material of the infrared window film is a conductive film with infrared transmittance rate, so that infrared light irradiates the piezoelectric layer by transmitting the upper electrode; the acoustic wave reflection layer comprises a substrate, a support layer and an air cavity; the support layer is deposited on the substrate; the air cavity is formed between the substrate and the support layer; the piezoelectric oscillation pile is deposited on the support layer. The MEMS infrared sensor is small in size, low in production cost and simple in preparation process; the MEMS infrared sensor can be repeatedly used and is capable being produced in batches and integrating arrays, low in production cost, easily compatible with external circuits, free of refrigeration and sensitive to the overall infrared wave band.

A procedure for improved temperature control in controlled radical polymerization processes is disclosed. The procedure is directed at controlling the concentration of the persistent radical in ATRP and NMP polymerizations procedures and the concentration of radicals in a RAFT polymerization process by feeding a reducing agent or radical precursor continuously or intermittently to the reaction medium through one of more ports.

A phase shifter and method include a hybrid coupler being ground shielded. The hybrid coupler with reflective terminations connected to the hybrid coupler is configured to phase shift an applied signal wherein the reflective terminations include a parallel LC circuit.

A procedure for improved temperature control in controlled radical polymerization processes is disclosed. The procedure is directed at controlling the concentration of the persistent radical in ATRP and NMP polymerizations procedures and the concentration of radicals in a RAFT polymerization process by feeding a reducing agent or radical precursor continuously or intermittently to the reaction medium through one of more ports.

The invention relates to a high gain broadband dielectric lens Vivaldi antenna. The array antenna comprises a substrate, a radiation slot, a dielectric lens and a Chebychev tapered strip line feeder. According to the high gain broadband dielectric lens Vivaldi antenna, through changing the structural size of the dielectric lens, the fluctuation of antenna radiation impedance can be effectively improved so as to obtain better impedance matching, the transmission speed of an electromagnetic wave in the slot can be reduced according to the high dielectric constant of the lens, the current distribution on an antenna aperture is improved, thus a spherical wave is a nearly a plane wave, the antenna radiation efficiency is raised, and a higher antenna gain is obtained. According to a Chebychev tapered strip line, the impedance matching of the antenna can be improved further, and the working band is broadened. The array antenna in the invention has the characteristics of high gain and broad band and is suitable for a radiation unit of wideband array antennas of the field of mobile communication and a military radar.

The present invention is directed to addressing performance issues attributable to membrane electrode assemblies, and the components thereof, in electrochemical conversion cells. In accordance with one embodiment of the present invention, a device comprising at least one electrochemical conversion cell is provided. The cell is configured to convert first and second reactants to electrical energy and comprises a membrane electrode assembly and at least one membrane reinforcement layer. The combination of elastic modulus and thickness of the reinforcement layer and the bond between the reinforcement layer and the membrane electrode assembly are sufficient to enhance the structural integrity of the membrane electrode assembly beyond the operational degradation threshold of the assembly.

The invention provides a flame-retardant resin composition. The composition comprises hydrogenated styrene-butadiene block copolymers, polypropylene and/or polystyrene, a flame retardant and a compatilizer, wherein the composition also comprises silicone oil. The flame-retardant resin composition has good mechanical property and high stretching strength of 100 percent.

An additional fiber reinforced layer reduces crack propagation in a lightweight structure of an outer skin adhesively bonded to a reinforcing frame. For this purpose the additional fiber reinforced layer is interposed between the outer skin and the frame and adhesively bonded to the outer skin and to the frame. The additional layer has reinforcing fibers extending in parallel to each other or the reinforcing fibers are woven into a fabric embedded in a synthetic adhesive bonding material. The embedding of the parallel fibers or of the fiber fabric in the bonding material is performed either prior to the bonding or during the bonding of the additional layer to the outer skin and to the reinforcing frame.

The invention discloses a gamma-ray time detection device and a manufacturing method of a detector thereof. The device comprises the detector, a timing discriminator circuit, an amplifying forming circuit, a single channel pulse analyzer, a delay circuit, a time-amplitude conversion circuit, a coincident circuit and a multichannel analyzer. According to the gamma-ray time detection device and the manufacturing method of the detector thereof, a BaF2 crystal, POPOP and silicone rubber are adopted as materials for manufacturing a composite scintillation through adopting a special process, and processing to a honeycomb briquette shape to form the detector, so that fluorescent light with wave length being 220nm emitted by the BaF2 crystal can be converted to visible light with wave length being around 420nm, and a photoelectric multiplier of a quartz window is not needed anymore, so that the application range is greatly expanded; with the structural design of the honeycomb briquette shape, the surface area of the scintillation is increased, so that after part of flare light is refracted, the refracted flare light can be transmitted through air medium to reach a photoelectric detector, the time for reaching the photoelectric detector is shortened, the signal initial stage can be risen quickly, and a timing discriminator can be conductive to timing, so that the timing precision of the gamma-ray time detection device is improved.

Airfoil outer wall thickness of a gas turbine engine blade is increased in the zone that is proximate the trailing edge and blade hub by forty to sixty percent (40-60%) greater than comparable greatest wall thickness anywhere else along the trailing edge from outboard that zone all the way to the blade tip. The increased thickness zone includes a transition zone that bridges the respective airfoil outer wall thicknesses proximate the hub and tip of the blade. Some embodiments also incorporate pedestals with compound curve fillets in the increased wall thickness zone. The increased thickness zone reduces blade cracking propensity and enhances service life.

The invention discloses a rapid prediction system and method for bacterial drug resistance. The system comprises bacterial genomic DNA extraction equipment, bacterial genomic fingerprinting equipment,bacterial drug resistance phenotype determining equipment, bacterial drug resistance phenotype data collection and analysis equipment, an intelligent terminal, a cloud server and a bacterial databaseserver, wherein the bacterial genomic DNA extraction equipment is connected with the bacterial genomic fingerprinting equipment, the bacterial genomic fingerprinting equipment and the bacterial drugresistance phenotype data collection and analysis equipment are connected with the intelligent terminal through circuits or a wireless signals, the intelligent is connected with the cloud server through the Internet, and the cloud server is further connected with the bacterial database server. By utilizing the Internet and a safe cloud computing storage technique, the tolerance degrees of to-be-tested bacteria to different antibiotics can be accurately judged, and the heterogeneous drug resistance of the bacteria can be comprehensively judged according to information of genotypes and drug-resistant phenotypes.

The invention discloses an organic silicon flame-retardant pressure-sensitive adhesive tape. The organic silicon flame-retardant pressure-sensitive adhesive tape comprises a substrate layer, an adhesive agent layer and a release layer, wherein the substrate is a flame-retardant cotton paper layer; flame-retardant filler is filled with the inner part of the flame-retardant cotton paper layer; the flame-retardant filler is prepared from the following components in parts by weight: 30 parts to 50 parts of modified plant fibers, 8 parts to 10 parts of asbestos powder, 6 parts to 8 parts of flame-retardant fibers, 3 parts to 5 parts of nano-aluminum hydroxide, and 10 parts to 20 parts of vegetable glue. The invention also provides a preparation method of the organic silicon flame-retardant pressure-sensitive adhesive tape. The adhesive tape disclosed by the invention has high tensile strength, high softness performance, high viscosity and high stability while the adhesive tape has high flame retardance property; and compared with conventional halogen, the organic silicon flame-retardant pressure-sensitive adhesive tape is relatively high in flame retardance and is more environmentally friendly.

The invention discloses a buried sand high energy gas stress cracking method which mainly includes the steps of filling sand into the bottom, arranging a high energy gas stress cracking device, constructing a covering layer, detonating, cracking in a stress mode, and removing fillings. According to the method, the filling covering layer is filled into the upper portion well segment of the stress cracking device so that fast effusion of high energy gas can be limited, maintaining time of a high-temperature and high-pressure state of the high energy gas inside a well can be relatively prolonged under the common effect of inertia resistance of the filled fillings and cohesive force and frictional force between the high energy gas and the well wall, and therefore promotion of stress cracking effect is benefited. The method is free from constraint of equipment conditions and easy to implement, can block a large amount of gas energy, is reliable in effect of blocking gas, and enables application range of high energy gas stress cracking to be wide, and stress cracking effect to be obvious.

The invention discloses a dicycle surface plasmon super-slow wave planar microwave delay line comprising a dielectric substrate (1), a surface plasmon transmission line (2) arranged on the dielectricsubstrate (1) and coplanar waveguide to surface plasmon transmission line transition apparatuses (3), wherein two ends of the surface plasmon transmission line (2) are separately connected with two coplanar waveguide to surface plasmon transmission line transition apparatuses (3), the surface plasmon transmission line (2) is the transmission line of a dicycle structure, and a rectangular inner groove (20) array and a rectangular groove (21) array are arranged on the surface plasmon transmission line (2); and the working frequency band of the delay line is close to the high cut-off frequency ofthe surface plasmon transmission line (2). The delay line is uniform in delay within the working frequency band, and small in mutual coupling and size; the delay line is of a planar structure, capable of bending, easy to integrate and low in production cost.