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Fat-soluble substance for increasing male characteristics of males and applications thereof

A technology of fat-soluble substances and male organisms, applied in the field of fat-soluble substances, can solve the problems of increasing the number of stored sperm, achieve the effect of increasing testicular weight, increasing the number and density of stored sperm, and stabilizing product quality

Inactive Publication Date: 2015-09-23
INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, there are no patents and literature reports aimed at improving or enhancing certain male characteristics of male organisms (such as increasing testicular weight, increasing the number and density of sperm stored in the epididymis, etc.) at home and abroad.

Method used

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  • Fat-soluble substance for increasing male characteristics of males and applications thereof
  • Fat-soluble substance for increasing male characteristics of males and applications thereof
  • Fat-soluble substance for increasing male characteristics of males and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A. Culture of Haematococcus rich in astaxanthin

[0028] Select Haematococcus pluvialis, use the BG11 formula to make the medium (see Table 1), under the conditions of 22-25 ℃, and indoor natural diffuse light and assist with 50μE·m 2- ·S -1 Light intensity of light illumination, according to the rhythm of 14:10 light and darkness to cultivate Haematococcus algae species.

[0029] After culturing Haematococcus species for 12 days, the cells are in the logarithmic growth phase of rapid reproduction. Inoculate the algae cultivated to the logarithmic growth phase into the medium made with BG11 formula, and then continue to cultivate in the cultivation workshop at 20-25℃. The cultivation adopts natural daylight light source. The light intensity can be adjusted and controlled by the sunshade. 1000-2000μE·m 2- ·S -1 Within the scope, continue to expand the culture for 2 weeks.

[0030] The expanded Haematococcus algae strain is transferred to the open track pond bioreactor through ...

Embodiment 2

[0041] Male animal feeding and some male characteristics determination methods

[0042] Thirty male healthy Wistar rats (weight 150-160g) aged 4-5 weeks were selected, and they were observed for 1 week and then randomly divided into 3 groups (10 in each group, 5 in a cage). Separately mark and raise under the conditions of 23.0±3.0℃ temperature, 40-70% relative humidity, 12 / 12h light (light intensity 150-300 Lux), and air exchange 10-15 times / h. Among them, two groups were given the low- and medium-content Haematococcus fat-soluble mixture obtained in the above example according to the rat's kg body weight, wherein the active ingredient is carotenoids and their derivatives mainly containing astaxanthin. In the medium-dose group, the astaxanthin-based carotenoid was administered at 0.9 mg / kg body weight, and the astaxanthin-based carotenoid in the high-dose group was administered at 2.7 mg / kg body weight. Carry out the same gavage treatment with the same volume of vegetable oil. ...

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Abstract

The invention belongs to the field of biomedicine and health, and specifically relates to a unicellular algae fat-soluble substance for increasing male characteristics of males and applications thereof. The main active component of the fat-soluble substance is composed of natural carotenoid and oxidation derivatives thereof, or micro algae powder rich in the carotenoid and oxidation derivatives thereof. The natural fat-soluble mixed substance rich in carotenoid and oxidation derivatives thereof is extracted from unicellular algae, which is obtained though cell engineering large-scale culture. Furthermore, novel healthcare and medical products and biological preparations, which can improve or strengthen the male functions, are developed on the basis of feeding and verification on experiment animals, and the products and biological preparations are used to improve or strengthen certain male characteristics of males such as testis weight, stored sperm number and density in epididymis, and the like.

Description

Technical field [0001] The invention belongs to the field of biomedicine and health, and specifically is a fat-soluble substance for improving the male characteristics of male organisms and its application. Background technique [0002] Sexual characteristics are the most basic sign that sexual creatures distinguish between female and male sex, and it is also the basis for determining sex. In higher animals and humans, male characteristics mainly include: testis, epididymis, penis, seminal vesicles, vas deferens, prostate and bulbar urethra. Among them, the testis is the core organ in the above-mentioned male characteristics, which produces germ cell sperm and male hormones in the testis, which play a vital role in supporting the related functions of male animals. [0003] The testis is an important core organ that produces germ cell sperm and male hormones. The testis is composed of seminiferous tubules and interstitial cells. From the beginning of puberty, in the seminiferous ...

Claims

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Application Information

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IPC IPC(8): A61K31/122A61K31/047A61K31/015A61K36/05A23L1/29A23L2/38A61P15/00A61P15/08
Inventor 刘建国张勇龙元薷李倩倩刘倩
Owner INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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