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Medicament for treating steroid osteonecrosis of the femoral head

A technology for necrosis of the femoral head and hormones, applied in the field of medicine, can solve the problems of high disability rate, increase in the number of SANFH patients, damage, etc., and achieve remarkable results.

Inactive Publication Date: 2015-09-30
鲁驷原
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although long-term and heavy use of hormones can lead to SANFH, hormone therapy is irreplaceable in the treatment of certain diseases, which leads to a sharp increase in the number of patients with SANFH
SANFH has the characteristics of short onset, rapid progression, and poor prognosis. The gradual development of the disease will lead to irreversible damage and high disability rate, which will bring huge economic and mental pressure to patients and society, and seriously affect the quality of life of patients.

Method used

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  • Medicament for treating steroid osteonecrosis of the femoral head
  • Medicament for treating steroid osteonecrosis of the femoral head
  • Medicament for treating steroid osteonecrosis of the femoral head

Examples

Experimental program
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Effect test

Embodiment

[0015] Example Preparation of the medicament of the present invention

[0016] Taking patch as an example, the preparation process of the medicament of the present invention is as follows:

[0017] (1) Weigh 120 grams of Dietatum chinensis, 150 grams of rose apple shells, 150 grams of Baiyancai, 120 grams of white hair snake, and 100 grams of palm wood, add 6000 milliliters of water, and heat and reflux in a flask equipped with a condenser tube for 4 After cooling to room temperature, filter, add ethanol to the filtrate until the alcohol content is 80% by volume, place it at room temperature for 24 hours and filter, recover the ethanol in the filtrate and evaporate the aqueous solution to obtain dry paste 1;

[0018] (2) Weigh 150 grams of vine vine, 50 grams of piercing stone, 150 grams of carambola root, and 120 grams of rusty nails, add 6000 milliliters of water, filter after heating for 1 hour under reflux, and add 2mol / L hydrochloric acid aqueous solution in the filtrate ...

experiment example

[0021] Experimental example The curative effect of the medicament of the present invention

[0022] 1 Materials and methods

[0023] 1.1 General information

[0024] In this group, there were 60 patients with steroid-induced necrosis of the femoral head, all of which conformed to the guidelines for the diagnosis and treatment of femoral head necrosis in the "Guiding Principles for Clinical Research of New Chinese Medicines in the Treatment of Aseptic Necrosis of the Femoral Head", excluding those with a clear history of hip trauma and congenital Developmental deformities of the hip joint. The staging standard refers to the Ficat staging table.

[0025] 60 patients were divided into a treatment group of 30 cases and a control group of 30 cases. In the treatment group, there were 18 males and 12 females; the age of the patients ranged from 24 to 51 years old, with an average age of 37.7 years; 20 cases of single hips and 10 cases of double hips; 5 hips in stage I, 18 hips in ...

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Abstract

The invention relates to a medicament for treating steroid osteonecrosis of the femoral head. The medicament for treating steroid osteonecrosis of the femoral head comprises the following materials in parts by weight: 1 to 10 parts of carthamus tinctorius L., 10 to 20 parts of bruiseweed, 10 to 20 parts of shells of Syzygium jambos (L.) Alston, 5 to 15 parts of angelica sinensis, 1 to 10 parts of valeriana jatamansi jones, 10 to 20 parts of hairy clovershrub root, 5 to 15 parts of radix cyathulae, 10 to 20 parts of tinospora sinensis, 5 to 15 parts of radix salviae miltiorrhizae, 10 to 20 parts of delavay raspberry, 1 to 10 parts of radix cudramiae, 5 to 15 parts of rhizoma drynariae, 5 to 15 parts of field melasma herb, 10 to 20 parts of Hydrangea panicnlata Sieb.var. grandiflora Sieb.,1 to 10 parts of myriaceis nepalensis Less., 1 to 10 parts of Myriaceis nepalensis Less., 1 to 10 parts of liquorice, 5 to 15 parts of wood of Henry ormosia, 10 to 20 parts of morinda parvifolia, 1 to 10 parts of all-grass of twocolor velvet plant, 10 to 20 parts of humata tyermanni and 10 to 20 parts of averrhoa carambola L.root. The medicament provided by the invention has synergistic effects of supplementing each other and plays the effects of assisting and guiding together, takes the effects of promoting blood circulation to remove blood stasis and resolve toxin and disperse swelling as majors, plays assisting effects of tonifying the spleen and nourishing the liver, and clearing away heat and removing dampness, has a remarkable effect on treating steroid osteonecrosis of the femoral head, and is worthy of clinical application and application.

Description

[0001] The present invention is a divisional application of a patent with the application number 201510066342.8, the application date is February 10, 2015, and the invention title is "a medicament for treating steroid-induced necrosis of the femoral head". technical field [0002] The invention relates to the field of medicine, in particular to a medicament for treating steroid-induced necrosis of the femoral head. Background technique [0003] Necrosis of the femoral head is one of the intractable diseases in orthopedic diseases, among which steroid-induced necrosis of the femoral head (SANFH) accounts for a considerable proportion of the necrosis of the femoral head, and its incidence has accounted for non-traumatic necrosis. The first place in femoral head necrosis. Although long-term and heavy use of hormones can lead to SANFH, hormone therapy is irreplaceable in the treatment of certain diseases, which leads to a sharp increase in the number of patients with SANFH. SAN...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/80A61P19/08A61K35/583
Inventor 李福军
Owner 鲁驷原
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