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Effect of olive polyphenol on improving deterioration of aging-related movement function

A technology of olive polyphenols and motor function, which is applied in the field of improving effect of olive polyphenols on aging-related motor function decline, can solve the problem of no improvement effect of olive polyphenols on motor function decline, and achieve the effect of reliable research basis

Inactive Publication Date: 2015-11-11
XI AN JIAOTONG UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] After searching, no literature was found to record the improvement effect of olive polyphenols on aging-related motor function decline

Method used

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  • Effect of olive polyphenol on improving deterioration of aging-related movement function
  • Effect of olive polyphenol on improving deterioration of aging-related movement function

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Experimental program
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Effect test

Embodiment Construction

[0016] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

[0017] Male C57BL / 6J mice aged 2.5 months were randomly divided into two groups A and B, and male C57BL / 6J mice aged 15.5 months were randomly divided into two groups C and D. Among them, groups B and D were taken as the experimental group, and they were given olive polyphenol (HT-Ac aqueous solution) for intervention by intragastric administration; groups A and C were taken as the control group, and they were given corresponding volumes of water. The body weight and food intake of the experimental mice were monitored weekly, and the experiment lasted for 20 weeks. After 20 weeks of HT-Ac intervention, the mice were subjected to Rotarod performance test. The specific plan is shown in the table below:

[0018] group

number of mice

Starting month age

intervene

intervention dose

Group A - Young Group

15

2....

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Abstract

The invention discloses an effect of olive polyphenol on improving deterioration of an aging-related movement function. Compared with the prior art, the invention explores an effect of polyphenol ingredients in natural nutrient olive oil obtained from food in treating deterioration of the aging-related movement coordination ability, provides a new research medicine and a new medical way for treating age-related diseases, and also provides a reliable research basis and a considerable prospect for medical application of polyphenol ingredients in olive oil.

Description

technical field [0001] The present invention relates to the improving effect of olive polyphenols on aging-related motor function decline. Background technique [0002] Olive polyphenols (ac-HT) have antioxidant capacity, can reduce the degree of oxidation of low-density lipoproteins, and prevent coronary heart disease and atherosclerosis. Olive polyphenols also have the ability to relax vascular smooth muscle and lower blood pressure. [0003] Modern physical and chemical analysis studies have shown that the main components contained in olives are polyphenolic compounds, such as gallic acid, gallic acid, brevifolia hematoxylin, hyperoside and 3,3'-dimethoxy gallic acid, etc. quality polyphenol compounds, among which the three types of polyphenols, elemi, sandalwood, and trigonum, have the highest content. Modern pharmacological studies have shown that olive polyphenols have the functions of enhancing immunity, anti-oxidation, anti-virus, anti-bacterial, anti-inflammatory ...

Claims

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Application Information

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IPC IPC(8): A61K36/32A23L1/29A61P39/06A61P25/14A61P25/00A23L33/00
Inventor 龙建纲刘健康王永耀秦川祁红斌
Owner XI AN JIAOTONG UNIV
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