High-flux transcriptome sequencing data quality control method based on multi-core CPU (Central Processing Unit) hardware

Abstract

The present invention provides a high-flux transcriptome sequencing data quality control method based on multi-core CPU hardware. The method comprises: performing parallel processing on high-flux transcriptome sequencing data by using a multi-core CPU, so as to obtain data without low sequencing quality sequences; performing prediction and removal on rRNA sequences in the data without the low sequencing quality sequences by using the multi-core CPU, and performing qualitative identification on polluted sequences; and performing statistics and evaluation on a sequence comparison result. According to the high-flux transcriptome sequencing data quality control method based on the multi-core CPU hardware, provided by the present invention, based on a multi-core CPU computer, a computing efficiency bottleneck based on a single-core CPU hardware computer is overcome, so that high-flux transcriptome data quality control efficiency is increased by over 7 times; and by applying the high-flux transcriptome sequencing data quality control method, the accuracy and speed of the high-flux transcriptome data quality control are significantly improved, and rapid development of relevant researches of transcriptome sequencing is widely facilitated.

Description

technical field [0001] The patent of the present invention relates to bioinformatics, specifically a method for quality control of high-throughput transcriptome sequencing data based on multi-core CPU hardware, which can quickly perform quality control on high-throughput transcriptome sequencing data. Background technique [0002] High-throughput sequencing technology, also known as "next generation" sequencing technology, is a revolutionary change to traditional sequencing. It can sequence hundreds of thousands to millions of DNA / RNA molecules at a time, and has been more and more widely used. in biological research. Compared with traditional Sanger sequencing technology, the throughput of next-generation sequencing technology has increased by one to two orders of magnitude, and the amount of data is larger (100MB to several G). Transcriptome sequencing is an in-depth application based on high-throughput sequencing technology, which can conduct detailed, in-depth and compr...

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Problems solved by technology

[0004] In order to solve the problem that traditional analysis methods and computing systems cannot comprehensively, accurately and efficiently meet the quality control requirements of high-throughput transcriptome sequencing data, the present invention proposes a method based on the parallel processing characteristics of high-throughput transcriptome sequencing data. High-throughput transcriptome sequencing data quality control method based on multi-core CPU hardware

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