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Application of traditional Chinese medicine composition to preparing medicine treating chronic stable angina pectoris

A composition and stability technology, applied in the preparation of drugs for the treatment of chronic stable angina pectoris, in the field of traditional Chinese medicine compositions, can solve problems such as rebound and facial flushing, and achieve good safety and good curative effect

Inactive Publication Date: 2016-03-16
GUIZHOU BAILING GRP PARMACEUTIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, nitroglycerin tablets and compound Danshen dripping pills are mainly used to relieve chronic stable angina pectoris in China, but nitrate preparations are prone to tolerance, and some patients may experience dizziness, headache, facial flushing and other adverse reactions after taking them, so stop using them rebound phenomenon
In addition, existing drugs and dosage forms for the treatment of chronic stable angina can only meet certain market demands

Method used

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  • Application of traditional Chinese medicine composition to preparing medicine treating chronic stable angina pectoris
  • Application of traditional Chinese medicine composition to preparing medicine treating chronic stable angina pectoris

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Embodiment 1

[0011] Embodiment two.

Embodiment 2

[0013] Embodiment three.

Embodiment 3

[0015] The present invention can also be prepared into other dosage forms such as tablets, granules, syrups, etc. according to conventional preparation techniques.

[0016] In order to confirm that the obtained product has an effective therapeutic effect, we have carried out a series of clinical experimental studies. The present invention treats the main therapeutic effect of chronic stable angina pectoris as follows:

[0017] 1. Patients and Methods

[0018] 394 cases of patients with chronic stable angina, randomized controlled clinical research on the treatment of chronic stable angina.

[0019] The randomized trial group and the control group were allocated 1:1. The experimental group was given Yindan Xinnaotong Soft Capsules, 4 capsules each time, 3 times a day, orally, and at the same time took the compound Danshen dripping pill simulation agent for 8 consecutive weeks; the control group was given Compound Danshen dripping pills, 10 pills each time , 3 times a day, or...

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Abstract

The invention discloses application of a traditional Chinese medicine composition to preparing medicine treating chronic stable angina pectoris. The composition is soft capsules prepared through a conventional preparation technology with ginkgo leaves, herba erigernotis, salviae miltiorrhizae, borneol, hawthorn fruits, gynostemma pentaphyllum, panax notoginseng and garlic as raw materials. The composition is prepared according to Miao medicine theories. The preparation is good in medicine component dissolution, high in bioavailability, little in dose and stable in drug property. The composition can be used for treating thoracic obstruction, breast pain, chest distress, hard breath, palpitation and the like caused by qi stagnation and blood stasis. The traditional Chinese medicine preparation has the functions of promoting blood circulation to remove blood stasis and tonifying qi and stopping pain.

Description

technical field [0001] The invention relates to an application of traditional Chinese medicine, in particular to the application of a traditional Chinese medicine composition in the preparation of medicine for treating chronic stable angina pectoris. Background technique [0002] Angina pectoris is a common and frequently-occurring disease that seriously endangers human beings, especially middle-aged and elderly people. At present, there is no good curative drug. At present, nitroglycerin tablets and compound Danshen dripping pills are mainly used to relieve chronic stable angina pectoris in China, but nitrate preparations are prone to tolerance, and some patients may experience dizziness, headache, facial flushing and other adverse reactions after taking them, so stop using them Afterwards, there is a rebound phenomenon. In addition, the existing drugs and dosage forms for the treatment of chronic stable angina can only meet certain market demands. Therefore, clinically o...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P9/10A61K31/045
Inventor 成龙梁日欣许海玉
Owner GUIZHOU BAILING GRP PARMACEUTIAL CO LTD
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