Esophageal-mucosa staining combination set

A technology of esophageal mucosa and suit, which is applied in the field of esophageal mucosa dyeing combination suit, which can solve the problems of no iodine solution and heavy irritation of iodine solution, and achieve the effects of rapid neutralization, elimination of discomfort and convenient use

Inactive Publication Date: 2016-03-16
JIANGSU CHENGPIN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problems in the prior art that there is no suitable iodine solution available for direct use and that the existing iodine solution is too irritating, the present invention provides a diagnostic kit for esophageal mucosa staining. It can directly stain the esophageal mucosa with staining solution, which is convenient to use and has good staining effect. It is specially equipped with neutralizing reagents, which can quickly eliminate the adverse reactions of iodine solution

Method used

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  • Esophageal-mucosa staining combination set
  • Esophageal-mucosa staining combination set
  • Esophageal-mucosa staining combination set

Examples

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Effect test

Embodiment 1

[0029] A combination kit for esophageal mucosa staining, consisting of staining solution and neutralizing solution; the staining solutions are KI and I 2 The compound solution, wherein in the staining solution I 2 The mass percentage concentration is 1%-2.5%; the neutralizing solution is an aqueous solution of sodium thiosulfate with a mass percentage concentration of 1%-3.5%. Sodium carbonate is also added to the neutralizing solution, and the mass percent concentration of sodium carbonate in the neutralizing solution is 0.01%-0.03%. The mass percent concentration of potassium iodide in the staining solution is 3.5%-4.5%.

[0030] Table 1. The proportioning table of embodiment 1

[0031]

Embodiment 2

[0033] An esophageal mucosa staining combination set is characterized in that it consists of a staining solution and a neutralizing solution; the staining solutions are KI and I 2 The compound solution, wherein in the staining solution I 2 The mass percentage concentration is 1%-2.5%; the neutralizing solution is an aqueous solution of sodium thiosulfate with a mass percentage concentration of 3.6%-5%. Sodium carbonate is also added to the neutralizing solution, and the mass percent concentration of sodium carbonate in the neutralizing solution is 0.01%-0.03%. The mass percent concentration of potassium iodide in the staining solution is 3.5%-4.5%.

[0034] Table 2. The proportioning table of embodiment 2

[0035]

Embodiment 3

[0037] The application of an esophageal mucosa staining combination kit is used for endoscopic diagnosis staining of early esophageal cancer.

[0038] Specific operation under the endoscope: place the endoscope about 20cm away from the incisors. Insert the nozzle from the biopsy pipeline, slowly enter the mirror, and at the same time, the assistant injects 20ml of iodine solution with a mass percentage concentration of 1.0%-2.5% in the staining solution bottle in the kit of the present invention from the nozzle, from top to bottom, so that the dye The liquid is evenly sprayed on the entire esophageal mucosa (it can also be sprayed from bottom to top). Before staining, care should be taken to clean the mucus on the surface of the esophageal mucosa. Immediately after spraying the staining solution, rinse the esophageal wall with 10-20ml of water, rinse and absorb the remaining staining solution and mucus in the esophagus, enter the gastric cavity to absorb the staining solution,...

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Abstract

The invention discloses an esophageal-mucosa staining combination set. The esophageal-mucosa staining combination set is characterized by being prepared from a staining solution and a neutralization solution; the staining solution is a compounded solution of KI and I2, wherein the mass percent concentration of the I2 in the staining solution is 1%-2.5%; the neutralization solution is a sodium thiosulfate aqueous solution with the mass percent concentration of 1%-3.5%. The esophageal-mucosa staining combination set is a combination set kit of the compounded iodine stain and a neutralization reagent, and is stable in concentration, convenient to use, rapid in neutralization and capable of rapidly removing discomfort of a patient.

Description

technical field [0001] The invention relates to an endoscopic diagnostic staining kit set for early esophageal cancer, in particular to an esophageal mucosa staining combination set with a staining solution and a neutralizing solution. It is suitable for screening and auxiliary diagnosis of early esophageal cancer and precancerous lesions under endoscopy. It can also be used to quickly eliminate adverse reactions of iodine solution. Background technique [0002] my country is a country with a high incidence of esophageal cancer, and its harm is especially serious in high-incidence areas. Although decades of efforts have been made in the prevention and treatment of esophageal cancer, the therapeutic effect is not satisfactory. This is mainly because there are few typical symptoms in the early stage of esophageal cancer, and most of the patients who seek treatment due to symptoms are in the middle and late stages, and the clinical treatment effect of middle and late cancers ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/00
CPCA61K49/0006
Inventor 许均卫
Owner JIANGSU CHENGPIN BIOTECH
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