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Plumeria rubra drop pill and preparation method thereof

A technology of frangipani and flower dripping pills, which is applied in the fields of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients. It can solve the problems of low extraction rate, insufficient introduction of medicinal ingredients, and high cost, and achieve high inhibition. Blood pressure disease, increase utilization value, and increase the effect of stability

Inactive Publication Date: 2016-04-06
ZHAOQING MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a frangipani dripping pill, which solves the problems of high cost, low extraction rate and insufficiently proposed medicinal components in the prior art

Method used

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Examples

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Effect test

preparation example Construction

[0027] The present invention also provides a preparation method of frangipani dripping pills, specifically comprising the following steps:

[0028] Step 1. Preparation of frangipani extract: crush the dried frangipani flower and cold-soak for 0.5 h, then add 10-15 times the amount of water for reflux extraction, the reflux extraction temperature is 55-65°C, and the number of extractions is 2-3 times. Combine the extracts for 0.5-2 hours each time, filter, concentrate the filtrate at 75°C and a vacuum of 0.075 MPa to an extract with a relative density of 1.25-1.35, let cool, add 4-6 times 50-80% ethanol, and stir Let it stand evenly for 24-72 hours, filter out the supernatant, recover ethanol under reduced pressure at 75°C and 0.075MPa until there is no alcohol smell, continue to concentrate at 75°C to a thick paste with a relative density of 1.20-1.30, and transfer it to a vacuum drying oven , vacuum-dried to dryness at 60°C and 0.08MPa, and crushed through a 120-140 mesh siev...

Embodiment 1

[0033] A preparation method for Frangipani dripping pills, specifically comprising the following steps:

[0034] Step 1. Preparation of frangipani extract: crush the dried frangipani flower and cold-soak for 0.5h, add 10 times the amount of water for reflux extraction, the reflux extraction temperature is 55°C, the extraction times are 2 times, each time for 0.5 hours The liquids were combined, filtered, and the filtrate was concentrated to an extract with a relative density of 1.25 at 75°C and a vacuum of 0.075MPa, let cool, added 4 times 50% ethanol, stirred evenly and stood for 24h, filtered out the supernatant, 75°C, Recover ethanol under reduced pressure at 0.075MPa until there is no alcohol smell, continue to concentrate at 75°C to a thick paste with a relative density of 1.20, transfer it to a vacuum drying oven, dry it in vacuum at 60°C and 0.08MPa, and crush it through a 120-mesh sieve , to get the main drug fine powder. During the reflux extraction process, the soli...

Embodiment 2

[0039] A preparation method for Frangipani dripping pills, specifically comprising the following steps:

[0040] Step 1. Preparation of frangipani extract: crush the dried frangipani flower and cold-soak for 0.5h, double the amount of water for reflux extraction, the reflux extraction temperature is 65°C, the number of extractions is 3 times, each time 2 hours, and the extracts are combined , filter, concentrate the filtrate to an extract with a relative density of 1.35 at 75°C and a vacuum of 0.075MPa, let it cool, add 6 times 80% ethanol, stir evenly and let it stand for 72h, filter out the supernatant, 75°C, 0.075MPa Recover ethanol under reduced pressure until there is no alcohol smell, continue to concentrate at 75°C to a thick paste with a relative density of 1.30, transfer it to a vacuum drying oven, dry it in vacuum at 60°C and 0.08MPa, and crush it through a 120-140 mesh sieve , to get the main drug fine powder. During the reflux extraction process, the solid-liquid ...

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Abstract

The invention discloses a plumeria rubra drop pill. The plumeria rubra drop pill is prepared from the following components in parts by weight: 1-4 parts of plumeria rubra extract, 1-2 parts of edible bird's nest extract, 13-35 parts of a substrate, and 0.1-0.4 part of a cosolvent. The invention further discloses a preparation method of the plumeria rubra drop pill. According to the invention, the traditional herbal tea is prepared into the drop pill, so that the production and carry are convenient, the instant drinking purpose is realized, the plumeria rubra drop pill is suitable for both the aged and the young, the problems that abundant time is consumed and the operation is complicated when the traditional herbal tea is used are solved, and the utilization value of the herbal tea is greatly improved. The prepared plumeria rubra drop pill has a certain effect of inhibiting hypertension.

Description

technical field [0001] The invention belongs to the technical field of health-care tea, and in particular relates to a frangipani dropping pill, and also relates to a preparation method of the frangipani dropping pill. Background technique [0002] In Guangdong area, the white frangipani is often dried to make herbal tea, which is very popular; it is cool in nature, sweet and light in taste; it belongs to the large intestine and stomach meridians, and has the effects of moistening lungs and detoxification, clearing away heat and dampness, and smoothing intestines. For example, "Lingnan Caiyaolu" says that it can "cure damp-heat diarrhea, tenesmus and heavy tongue, and moisten the lungs and detoxify". Although bitter gourd is bitter, its bitter taste is cool in nature. It feels cool and comfortable after eating on a hot day, and it has the effect of clearing the heart and appetizing. [0003] At present, the use of frangipani generally remains on traditional herbal tea decoc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/24A61K9/20A61P9/12A61K35/57
CPCA61K36/24A61K9/0095A61K9/2018A61K9/2031A61K35/57A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2236/55A61K2300/00
Inventor 保泽庆吴伟斌陈妙茹
Owner ZHAOQING MEDICAL COLLEGE
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