Roselle-Green Tea Composition for Amelioration of Diet-Induced Metabolic Disorders

Abstract

The invention relates to application of a hibiscus sabdariffa-green tea composition in relieving diet-induced metabolic disorders, and particularly provides an aqueous extract and a composition with the same. The aqueous extract is the aqueous extract of the mixture of hibiscus sabdariffa flower and green tea or is the mixture of a hibiscus sabdariffa aqueous extract and a green tea aqueous extract. It is found that the hibiscus sabdariffa aqueous extract and the green tea aqueous extract can remarkably relieve weight increment of the body and epididymis fat of a mouse induced by high-fat and high-sugar diet, lower blood glucose and blood fat, improve mouse liver fat deposition and increase insulin sensitivity, while has no obvious influence on the food intake and water intake of the mouse. It is also found that the hibiscus sabdariffa-longjing tea composition extracting solution can lower fatty liver by increasing liver fatty acid oxidation and lowering lipid synthesis; in addition, insulin resistance can be lowered in the way of restraining mTORC1 / S6K.

Description

technical field [0001] The present invention relates to the use of a roselle-green tea composition for improving diet-induced metabolic disorders. Background technique [0002] With the improvement of living standards and changes in dietary structure, the incidence of metabolic syndrome (MS) with obesity, non-alcoholic fatty liver disease, hyperinsulinemia, hypertension, and hyperlipidemia as phenotypes has increased year by year. With a trend of rejuvenation, it has become a type of disease that endangers human health [Alberti, K.G., P.Zimmet, and J.Shaw, Metabolic syndrome--a new world-wide definition. A Consensus Statement from the International Diabetes Federation, Diabet Med , 2006, 23(5): p.469-80]. Among them, the relationship between glucose and lipid metabolism and health has been paid more and more attention. Hyperlipidemia caused by lipid metabolism disorder is an important factor in other chronic diseases such as fatty liver, obesity, coronary heart disease and...

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Problems solved by technology

For example, Geng Jingzhang and others have studied the compound beverage of honeysuckle and green tea [Geng Jingzhang and Lu Zhiyuan, "Technology optimization of honeysuckle and green tea compound beverage", "Food Industry", 2010(04):p.69-71]; Zhou Huiheng et al. Roselle, Dian black tea, green tea compound beverage [Zhou Huiheng, Wu Rongshu and Wang Yashen, "Development of roselle, Dian black tea, green tea compound beverage", "Beverage Industry", 2011(07):p .25-27]; Ren Hong etc. have studied the composite drink of green tea and white chrysanthemum [Ren Hong et al., "Research and development of partridge tea, green tea, and white chrysanthemum compound drink", "Food Research and Development", 2013 (07): p.81-84], etc., but relatively insufficient research on the mechanism of health effects of green tea and scented tea

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