Implanted multifunctional double-side micro brain electrode array chip

Abstract

The invention provides an implanted multifunctional double-side micro brain electrode array chip. Three electric pulse stimulation electrodes, four electrochemical detection electrodes and seven brain electric detection electrodes are distributed on each surface of an electrode pole; the electric pulse stimulation electrodes, the brain electric detection electrodes and the electrochemical detection electrodes are symmetrically distributed on the central axis of the two surfaces of the electrode pole; the electrochemical detection electrodes and the brain electric detection electrodes are connected to electrode lead interface welding discs via detection electrode leads; the electric pulse stimulation electrodes are connected to the electrode lead interface welding discs via stimulation electrode leads; and the electrode lead interface welding discs are symmetrically distributed at the two sides of the central axis of the two surfaces of an electrode handle. The electrodes of different functions are integrated on one chip so that electric pulse stimulation of deep brain tissues can be realized and the brain electric signals and electrochemical signals of the specific areas of the brain can be detected, the chip is suitable for being implanted in the brain for a long time and thus treatment and research of neurological diseases can be assisted.

Description

technical field [0001] The invention relates to the technical field of micro-electromechanical processing and the technical field of implanted micro-electrodes, in particular to an implanted multi-functional double-sided micro-brain electrode array chip. Background technique [0002] In the field of medical rehabilitation, to treat diseases such as Parkinson's syndrome, severe epilepsy and various addictions, surgical operations are usually used to implant brain electrodes near the lesion and give electrical stimulation with a certain frequency, pulse width and amplitude for treatment. . At present, Medtronic products are mainly used clinically to treat patients with deep brain stimulation (DBS). Although DBS is widely used clinically, its mechanism of action is still unclear. For a long time, people have used patch clamp, metal microelectrodes and glass microelectrodes to conduct electrophysiological basic research and animal experiments on nerve cells in vivo or in vitro....

AI Technical Summary

Problems solved by technology

[0004] Based on micro-electromechanical system technology (MEMS), through micro-nano processing technology, the electrode functional areas are reasonably planned and arranged on both sides of the silicon-based electrode, so as to realize the detection of EEG signals and electrochemical signals at the same time as electrical pulse stimulation. see related reports

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