Hydroxyapatite toothpaste and preparation method thereof

A technology of hydroxyapatite and nano-hydroxyapatite, which is applied in the field of daily chemical products, can solve the problems of easy failure of nano-hydroxyapatite and inability to repair dentin, etc., so as to promote the mineralization process, reduce the pore size, improve the The effect of the repair function

Active Publication Date: 2016-06-08
HANGZHOU JIAOJIE ORAL HEALTH CARE PRODS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented technology describes an improved type of toilet cleaning agent that contains tiny particles called nanoparticles made from colloidal silica (SiO2) suspended by water molecules. These Si02particle sizes are smaller compared to traditional methods like chlorhexidone gelatin capsule agents while still maintaining their effectiveness at rebuilding enamel surfaces. Additionally, this new formulation can be easily produced without adding any chemical substances during its production.

Problems solved by technology

The technical problem addressed in this patents relates to improving the efficiency of dentifrice compositions for treating dentinal issues caused by acid attack without losing their ability to restore them through remineralisation processes like decalcification. This requires nanoporous calcium phosphate (nano-HA) particles with high stability against environmental factors such as acids while being able to effectively reconstruct damaged surfaces within minutes after use.

Method used

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  • Hydroxyapatite toothpaste and preparation method thereof
  • Hydroxyapatite toothpaste and preparation method thereof
  • Hydroxyapatite toothpaste and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0059] This embodiment provides a hydroxyapatite toothpaste, which is calculated by mass percentage and consists of the following raw materials:

[0060] Calcium hydrogen phosphate dihydrate 12wt%, hydrated silica 10wt%, carrageenan 2wt%, glycerin 28wt%, sucralose 0.1wt%, zinc citrate 0.05wt%, sodium lauryl sulfate 2wt%, monofluorophosphoric acid Sodium 0.76wt%, peppermint flavor 1.25wt%, lemon yellow pigment 0.005wt%, micron hydroxyapatite 4wt%, nano hydroxyapatite 1wt%, and the balance is deionized water.

[0061] The method for preparing hydroxyapatite toothpaste includes the following steps:

[0062] S1. Put the above components in a mixer and stir for 40 minutes at 800 rpm;

[0063] S2, vacuum degass into a paste.

[0064] Such as figure 1 As shown, the average particle size of micron hydroxyapatite is 2μm; figure 2 As shown, the average particle size of nano-hydroxyapatite is 60 nm.

Embodiment 2

[0066] This embodiment provides a hydroxyapatite toothpaste, which is calculated by mass percentage and consists of the following raw materials:

[0067] Calcium hydrogen phosphate dihydrate 12wt%, carrageenan 2wt%, glycerin 28wt%, sucralose 0.1wt%, zinc citrate 0.05wt%, sodium lauryl sulfate 2wt%, sodium monofluorophosphate 0.76wt%, peppermint flavor 1.25wt%, lemon yellow pigment 0.005wt%, hydrated silica 10wt%, micron hydroxyapatite 3wt%, nano hydroxyapatite 2wt%, and the balance is deionized water.

[0068] The average particle size of micron hydroxyapatite is 2 μm, and the average particle size of nano-hydroxyapatite is 60 nm.

[0069] The method for preparing hydroxyapatite toothpaste includes the following steps:

[0070] S1. Put the above components in a mixer and stir for 40 minutes at 800 rpm;

[0071] S2, vacuum degass into a paste.

Embodiment 3

[0073] This embodiment provides a hydroxyapatite toothpaste, which is calculated by mass percentage and consists of the following raw materials:

[0074] Silica 40wt%, xanthan gum 0.02wt%, polyethylene glycol 40010wt%, methyl paraben 0.1wt%, sodium lauroyl sarcosinate 0.1wt%, sodium fluoride 8wt%, brilliant blue pigment 0.001wt %, micron hydroxyapatite 20wt%, nano hydroxyapatite 10wt%, and the balance is deionized water.

[0075] The average particle size of micron hydroxyapatite is 3 μm, and the average particle size of nano-hydroxyapatite is 80 nm.

[0076] The method for preparing hydroxyapatite toothpaste includes the following steps:

[0077] S1. Put the above components in a mixer and stir for 20 minutes at 100 rpm;

[0078] S2, vacuum degass into a paste.

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Abstract

The invention relates to hydroxyapatite toothpaste which comprises micron-order hydroxyapatite, nano-hydroxyapatite and fluoride. The grain size of the micron-order hydroxyapatite ranges from 0.1 micrometer to 10 micrometers, and the grain size of the nano-hydroxyapatite is smaller than 100 nm. The mass concentration of fluorine of fluoride in the hydroxyapatite toothpaste is not larger than 8.0 wt%, the mass content of the nano-hydroxyapatite is not larger than 20 wt%, and the mass ratio of the micron-order hydroxyapatite to the nano-hydroxyapatite is 1:10 to 18:1. When the hydroxyapatite toothpaste is used, demineralized dentine sheets are helped to be subjected to biomineralization, the dentin sheets are restored, the aperture of the dental canaliculi is reduced, and even the dentinal tubule is blocked or a hydroxyapatite layer is deposited on the surface of the dentin. At the same time, fluoride matched with the content of the micron-order hydroxyapatite and the content of the nano-hydroxyapatite is hydrolyzed to generate fluorinions, the mineralization process of the hydroxyapatite in the dentin is promoted, and the restoring function of the hydroxyapatite toothpaste on the dentin is remarkably improved.

Description

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Claims

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Application Information

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Owner HANGZHOU JIAOJIE ORAL HEALTH CARE PRODS
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