A preparation method of glycosylated Enteromorpha oligosaccharides for lowering blood sugar and regulating intestinal flora

A technology of intestinal flora and glycosylation, which is applied to medical preparations containing active ingredients, pharmaceutical formulations, digestive system, etc., and can solve the problem of the proliferation function of glycosylated oligosaccharides in reducing blood sugar and intestinal probiotics. Research and other issues to achieve the effect of improving commodity value and economic added value, simple operation and reducing production costs
CN105695537BActive Publication Date: 2019-11-19清枫链食苏打饮品(吉林)有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
清枫链食苏打饮品(吉林)有限公司
Publication Date
2019-11-19

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Abstract

The invention discloses a preparation method of glycosylation enteromorpha oligosaccharide for reducing glucose level and regulating intestinal flora. The method includes the steps of smashing enteromorpha in a superfine mode after drying, conducting backflow extracting through ethyl alcohol, conducting concentrating, drying and smashing to obtain defatted enteromorpha powder, removing protein, polysaccharide and pigment, adding fucosyltransferase into a reaction system containing enteromorpha oligosaccharide, and conducting fucus glycosylation reaction to prepare fucus glycosylation enteromorpha oligosaccharide. It is proved that glycosylation enteromorpha oligosaccharide has strong restraining activity for alpha-glucosaccharase, remarkably increases the number of intestinal probiotics, and can be used for preparing medicines or health care products for preventing and treating diabetes and improving metabolic diseases of intestinal flora and the like.
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Description

technical field

[0001] The invention belongs to the technical field of biopharmaceuticals, and relates to a method for preparing glycosylated Enteromorpha oligosaccharides for lowering blood sugar and regulating intestinal flora. Background technique

[0002] With the improvement of people's life, the population of hyperglycemia is expanding day by day, diabetes and blood circulation system diseases caused by hyperglycemia are more and more harmful to human health. Research data in recent years have shown that intestinal flora is closely related to type 2 diabetes. Bifidobacteria are the dominant genus in the human intestinal flora and one of the important signs of human health. The reduction of the number of bifidobacteria can lead to the dysbiosis of the whole intestinal flora and the imbalance of intestinal microecology, which leads to the occurrence of many metabolic diseases. Bifidobacteria can effectively improve glucose tolerance and glucose-induced insulin secretio...

Claims

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