A bioassay method and bioassay spray tower suitable for high-throughput pharmaceutical screening
A biological testing and high-throughput technology, applied in the field of agriculture, can solve the problems of testing drug dosage and cost limitations, reducing the use efficiency of chemicals, and large spray space distribution, so as to save chemical consumption, avoid uneven spraying, and save space. The effect of small distribution volume
Active Publication Date: 2018-08-10
NANJING AGRI MECHANIZATION INST MIN OF AGRI
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Problems solved by technology
[0004] In high-throughput screening, it is necessary to test a large number of samples, but there are often situations where there is a large amount of drugs and few drugs, so that the test work is limited by the amount of drugs and costs.
However, the existing biometric spray tower consumes a lot of chemicals, because the spray space distribution is large and the loss is high, which reduces the use efficiency of the chemicals, and is affected by the movement mode of the spray equipment, and there is also a phenomenon of uneven spraying
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[0028] In order to clarify the technical scheme and technical purpose of the present invention, the present invention will be further introduced below in conjunction with the accompanying drawings and specific embodiments.
[0029] Such as figure 1 The bioassay spray tower shown includes the following components:
[0030] 1) The housing is equipped with a closed working room isolated from the working environment. The working room is connected to the outside through the exhaust port 1, and is used to exhaust the air that has come into contact with the medicine to the outside of the working environment or to the gas treatment equipment. The casing is provided with a visible window 3 for observing the workroom, and a handle is installed outside the visible window 3 for easy opening; the top of the workspace is provided with a number of cleaning nozzles 2 with different nozzle angles for cleaning the workspace and avoiding the leakage of chemicals. Deposition affects the accuracy...
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The invention discloses a bioassay method applicable to high-throughput chemical screening and a bioassay spray tower.The bioassay method has the advantages that owing to small spraying spatial distribution volume of spray heads, loss rate of chemicals due to dispersion of droplets in air is decreased, non-uniformity in spraying due to time difference between starting a driving mechanism and starting the spray heads is avoided, chemical spraying quantity is controlled precisely, accuracy of the bioassay method is improved remarkably, chemical consumption is reduced, and accordingly the bioassay method is particularly applicable to high-throughput chemical screening.The bioassay spray tower is novel in structural design, saving in space, easy to produce and manufacture and worthy of being popularized and used.
Description
technical field [0001] The invention relates to the field of agricultural technology, in particular to a bioassay method and a bioassay spray tower suitable for high-throughput medicament screening. Background technique [0002] High throughput screening (HTS) technology is based on experimental methods at the molecular and cellular levels, using microplates as the carrier of experimental tools, using automated operating systems to execute the experimental process, and using sensitive and rapid detection instruments to collect Experimental result data, computer analysis and processing of experimental data, a large number of samples can be tested in a short period of time, and the technical system supported by the obtained corresponding database, it has the characteristics of trace, fast, sensitive and accurate, in short, it can Obtain a large amount of information through one experiment and find valuable information from it. [0003] The bioassay spray tower is an important...
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IPC IPC(8): A01M7/00
CPCA01M7/0025A01M7/0089
Inventor 张玲薛新宇金永奎周立新周良富孔伟朱忠伟顾伟崔龙飞王宝坤
Owner NANJING AGRI MECHANIZATION INST MIN OF AGRI