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Traditional Chinese medicine composition containing folium artemisiae argyi and capable of treating postpartum hemorrhage and preparation method thereof

A postpartum hemorrhage and composition technology, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of postpartum hemorrhage, can solve the problems of insufficient utilization of active ingredients of medicines, and achieve low incidence of adverse reactions, rapid onset, and reasonable compatibility Effect

Inactive Publication Date: 2016-07-20
GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinical trials have shown that the traditional Chinese medicine composition of the present invention has a certain effect on postpartum hemorrhage, but the preparation steps of this traditional Chinese medicine composition are too simple, the active ingredients of the medicine cannot be fully utilized, and in the clinical trials, the causes of postpartum hemorrhage in 200 cases have not been introduced , resulting in uncertainty about the treatment of postpartum hemorrhage by this traditional Chinese medicine composition

Method used

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  • Traditional Chinese medicine composition containing folium artemisiae argyi and capable of treating postpartum hemorrhage and preparation method thereof
  • Traditional Chinese medicine composition containing folium artemisiae argyi and capable of treating postpartum hemorrhage and preparation method thereof
  • Traditional Chinese medicine composition containing folium artemisiae argyi and capable of treating postpartum hemorrhage and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] The Chinese medicine composition of Example 1 of the present invention comprises the preparation raw material of following parts by weight:

[0043] 12 parts of mugwort leaf, 13 parts of big thistle, 8 parts of purslane, 9 parts of peony, 7 parts of ginseng, 8 parts of angelica, 5 parts of donkey-hide gelatin, 5 parts of Chuanxiong, 3 parts of Angelica dahurica, 2 parts of litchi, 3 parts of dried ginger and licorice 6 servings.

[0044] The preparation method is as follows:

[0045] S1. Weigh mugwort leaf, thistle, purslane, guanzhong, ginseng, angelica, donkey-hide gelatin, chuanxiong, angelica, lychee, dried ginger, licorice, remove impurities respectively, wash, dry, slice and crush into coarse powder, Add water according to 6 times the total weight of the coarse powder, decoct under reflux for 4 hours, filter, combine the filtrate, and concentrate under reduced pressure at 50°C to a medicinal extract with a relative density of 1.35;

[0046] S2. The medicinal ext...

Embodiment 2

[0050] Embodiment 2 of the present invention Chinese medicine composition comprises the preparation raw material of following parts by weight:

[0051] 25 parts of mugwort leaves, 24 parts of big thistle, 20 parts of purslane, 19 parts of peony, 18 parts of ginseng, 19 parts of angelica, 12 parts of donkey-hide gelatin, 5-15 parts of Sichuan, 12 parts of Angelica dahurica, 15 parts of litchi, 9 parts of dried ginger And licorice 10 parts.

[0052] The preparation method is the same as in Example 1.

Embodiment 3

[0054] Embodiment 3 of the present invention Chinese medicine composition comprises the preparation raw material of following parts by weight:

[0055] 19 parts of mugwort leaf, 13 parts of big thistle, 14 parts of purslane, 14 parts of coriander, 13 parts of ginseng, 13 parts of angelica, 8 parts of donkey-hide gelatin, 10 parts of Chuanxiong, 7 parts of Angelica dahurica, 8 parts of litchi, 6 parts of dried ginger and licorice 8 servings.

[0056] The preparation method is the same as in Example 1.

[0057] Pharmacodynamic study of Chinese medicine composition of the present invention:

[0058] Therapeutic effect of traditional Chinese medicine composition of the present invention on large animal model of postpartum hemorrhage in rats

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Abstract

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition containing folium artemisiae argyi and capable of treating postpartum hemorrhage and a preparation method thereof. The traditional Chinese medicine compound is prepared from the following raw materials in parts by weight: 12-25 parts of folium artemisiae argyi, 13-24 parts of Herba seu Radix Cirsii Japonici, 8-20 parts of Herba Portulacae, 9-19 parts of Cyrtomium Rhizome, 7-18 parts of radix ginseng, 8-19 parts of radix angelica sinensis, 5-12 parts of donkey-hide gelatin, 5-15 parts of Rhizoma Chuanxiong, 3-12 parts of radix angelicae, 2-15 parts of litchi fruit, 3-9 parts of rhizoma zingiberis and 6-10 parts of liquorice root. The traditional Chinese medicine composition conforms to the combination principle of monarch, minister, assistant and guide of traditional Chinese medicine and is reasonable in ingredients and has a mutually synergistic effect; all the herbs are coordinated in proper proportion, so that the traditional Chinese medicine composition has the effects of activating blood and eliminating stasis, reinforcing qi and nourishing blood, calming the liver and eliminating heat, and strengthening chong and stopping bleeding, is capable of effectively treating postpartum hemorrhage, and has the advantages of high pertinence, rapidness in effect taking, short treatment course, high cure rate and high safety.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition containing mugwort leaves for treating postpartum hemorrhage and a preparation method thereof. Background technique [0002] Postpartum hemorrhage occurs when the amount of bleeding exceeds 500 mL within 24 hours after delivery, and 80% of the cases occur within 2 hours after delivery. Late postpartum hemorrhage refers to the massive uterine bleeding that occurs in the puerperium 24 hours after delivery, and is more common in 1 to 2 weeks after delivery. Postpartum hemorrhage is a serious complication during childbirth and one of the four leading causes of maternal mortality. Postpartum hemorrhage has always been the first cause of maternal death in my country in recent years, especially in remote and backward areas. The incidence of postpartum hemorrhage accounts for 2% to 3% of the total number of de...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P15/00A61P7/04A61K35/36
CPCA61K36/9068A61K35/36A61K36/11A61K36/185A61K36/232A61K36/236A61K36/258A61K36/28A61K36/282A61K36/484A61K36/77A61K2236/331A61K2236/51A61K2300/00
Inventor 王一飞李风刘秋英利奕成
Owner GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
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