Compound preparation for treating bronchitis
A technology for bronchitis and compound preparations, applied in the field of compound preparations for the treatment of bronchitis, can solve the problems of difficulty in taking into account multiple aspects of curative effects, poor patient adaptability, etc., and achieve the effects of no toxic side effects, significant effects, and comprehensive curative effects.
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Embodiment 1
[0034] prescription:
[0035] Ambroxol 0.3 parts, erythromycin 0.2 parts, β-cyclodextrin 10 parts, loquat 20 parts,
[0036] 5 parts of tangerine peel, 5 parts of magnolia bark, 15 parts of asarum, 10 parts of trichosanthes, 50 parts of chitosan.
[0037] Preparation Process:
[0038] (1) Take β-cyclodextrin, add water and grind it into a paste; take ambroxol, add enough ethanol, ultrasonically dissolve, then add dropwise to the above-mentioned paste β-cyclodextrin, grind while dropping, and finish adding Then continue to grind, grind for 20min, and dry to get ambroxol clathrate;
[0039] (2) Weigh loquat, tangerine peel, magnolia officinalis, asarum and Trichosanthes in proportion, add 6 times the volume of 80% ethanol to reflux and extract once, each time for 2 hours, to obtain alcohol extraction residue and extract, and concentrate the extract, Obtain the alcohol extract, set aside;
[0040] (3) Remove the above-mentioned ethanol extraction residue, add 8 times the volu...
Embodiment 2
[0044] prescription:
[0045] 0.3 parts of ambroxol, 0.8 parts of erythromycin, 20 parts of α-cyclodextrin, 30 parts of loquat,
[0046] 15 parts of tangerine peel, 20 parts of magnolia bark, 25 parts of asarum, 30 parts of trichosanthes, 100 parts of sodium carboxymethyl cellulose.
[0047] Preparation Process:
[0048] (1) Take α-cyclodextrin, add water and grind it into a paste; take ambroxol, add enough ethanol, ultrasonically dissolve, and then add it dropwise to the above-mentioned α-cyclodextrin paste, grind while dripping, dropwise Continue to grind afterward, grind 40min, dry, obtain ambroxol clathrate;
[0049] (2) Take loquat, tangerine peel, magnolia officinalis, asarum and Trichosanthes in proportion, add 60% ethanol of 10 times the volume to reflux and extract 3 times, each time for 2 hours, to obtain alcohol extraction residue and extract, and the extract is concentrated, Obtain the alcohol extract, set aside;
[0050] (3) Remove the above-mentioned ethanol ...
Embodiment 3
[0054] prescription:
[0055] Ambroxol 0.3 parts, erythromycin 0.5 parts, α-cyclodextrin 15 parts, loquat 25 parts,
[0056] 10 parts of tangerine peel, 12.5 parts of magnolia bark, 20 parts of asarum, 20 parts of trichosanthes, 75 parts of ethyl cellulose.
[0057] Preparation Process:
[0058] (1) Take α-cyclodextrin, add water and grind it into a paste; take ambroxol, add enough ethanol, ultrasonically dissolve, and then add it dropwise to the above-mentioned α-cyclodextrin paste, grind while dripping, dropwise Then continue to grind, grind for 30min, dry to get ambroxol clathrate;
[0059] (2) Take loquat, tangerine peel, Magnolia bark, Asarum and Trichosanthes in proportion, add 8 times the volume of 70% ethanol to reflux and extract twice, each time for 2 hours, to obtain alcohol extraction residue and extract, the extract is concentrated, Obtain the alcohol extract, set aside;
[0060] (3) Remove the above-mentioned ethanol extraction residue, add 10 times the volum...
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