Fast cleaning method for gold-bearing matrix detection plate for cell analyzer

Abstract

The invention relates to a fast cleaning method for a gold-bearing matrix detection plate for a cell analyzer. The fast cleaning method comprises the steps of removing original liquid and washing holes of the detection plate through deionized water; adding pancreatin solutions into the holes for digestion; further cleaning the holes; washing the holes through absolute ethyl alcohol, drying the detection plate, and sterilizing the detection plate for backup use. According to the fast cleaning method, the gold-bearing matrix detection plate for the cell analyzer can be fast cleaned and can be repeatedly used on the premise of keeping the stability of experiment results, and therefore the detection cost can be lowered, and the market application prospect is good. The fast cleaning method is suitable for cleaning common cell culture plates and can lower the experiment cost.

Description

technical field [0001] The invention relates to a quick cleaning method for a gold-containing substrate detection plate used in a cell analyzer, and belongs to the field of cleaning molecular biology consumables. Background technique [0002] In recent years, the development of non-destructive, real-time and continuous new cell chip analysis technology has become more and more mature, and it has been gradually promoted and applied to various laboratories. Most cell microchips use electrochemical impedance technology based on gold substrates, such as the real-time cell detection and analysis system developed by ACEA Biosciences. This type of cell analyzer can detect dynamic biological reaction processes such as cell growth, proliferation, toxicity, adhesion and morphological changes in real time, and can be applied to many fields of basic applied science and new drug research and development. However, its core detection module uses high-purity gold substrate material consuma...

AI Technical Summary

Problems solved by technology

However, its core detection module uses high-purity gold substrate material consumables and can only be used once. For example, a box of detection modules used in a cell analysis system includes 6 plates, and each plate has 16 detection microchips (Plate16 ), the market price exceeds 2,000 yuan, which directly causes the detection cost to remain high

[0003] After searching, it was found that the Chinese invention patent application with application number 200910106775.6, application publication number CN101869894A, titled "Cleaning Device, Cleaning System, Cleaning Method and Particle Analyzer", and application number 201310298448.1, application publication number CN104289466A, titled "Cell Analysis In the existing technology represented by the Chinese invention patent application of "Invention Instrument and Its Cleaning System", there has not yet been a cleaning technology specifically for the gold-containing matrix detection plate used in the cell analyzer, which needs to be developed urgently

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