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Application of methyl liensinine in preventing and controlling skin photoaging

A technology of lysinine and skin photoaging, which is used in skin care preparations, skin diseases, medical preparations containing active ingredients, etc., to reduce oxidative damage, increase collagen, and improve wrinkles and pigmentation.

Active Publication Date: 2016-10-12
THE FIRST AFFILIATED HOSPITAL OF XIAN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, there is no relevant report on the prevention and treatment of skin photoaging by liensinine

Method used

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  • Application of methyl liensinine in preventing and controlling skin photoaging
  • Application of methyl liensinine in preventing and controlling skin photoaging
  • Application of methyl liensinine in preventing and controlling skin photoaging

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Embodiment Construction

[0038] The present invention will be further described in detail below in conjunction with specific embodiments, which are explanations of the present invention rather than limitations.

[0039] In the present invention, on the basis of constructing skin photoaging animals and cell models, the efficacy of nexinine in the prevention and treatment of skin photoaging is verified by scanning and transmission electron microscopy, HE, Masson staining, MTT, biochemical methods, etc. The results show that formazan Liensinine can improve the wrinkles and pigmentation of photoaging skin, increase the collagen of photoaging skin, reduce the oxidative damage of skin tissue and cells, and can be used for the preparation of medicines and cosmetics for preventing and treating skin photoaging.

[0040] The relevant experiments and results are as follows:

[0041] 1. Animal experiments on the therapeutic effect of liensinine on photoaging skin

[0042] 1.1 Establishment of animal experimental...

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PUM

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Abstract

The invention provides application of methyl liensinine in preventing and controlling skin photoaging. The methyl liensinine is an antioxidant alkaloid extracted from natural plants. On the basis of building a skin-photoaged animal and cell model, the effect of the methyl liensinine in preventing and treating skin photoaging is verified through scanning and transmission electron microscopy, HE (hematoxylin-eosin), Masson staining, MTT (methyl thiazolyl tetrazolium) assay, biochemical methods and other method, the results show that the methyl liensinine can improve wrinkles and pigmentation of photoaged skin, improve collagen in the photoaged skin and reduce oxidative damage of skin tissues and cells, may be used to prepare drugs and cosmetics for preventing and treating skin photoaging, and it is indicated that the effect of the methyl liensinine in preventing and treating skin photoaging is applicable to people having the daily need to prevent and treat photoaging damage. Therefore, the methyl liensinine may be used to prepare drugs and / or cosmetics for preventing and treating photoaging damage.

Description

technical field [0001] The invention belongs to the technical field of skin photoaging prevention and treatment, and in particular relates to the application of liensinine to prevent and treat skin photoaging. Background technique [0002] The skin aging process that is different from natural aging caused by ultraviolet rays in the sun is called photoaging. It is manifested as wrinkles, rough skin, dryness, relaxation, skin pigmentation, telangiectasia, and can even develop into benign or malignant tumors. With the destruction of the global ozone layer and the increase in the amount of ultraviolet radiation, there is a general trend of photoaging, and the incidence of skin tumors is also increasing year by year. How to cut off the occurrence and development of photoaging and protect skin tissue damage has become one of the research hotspots in related fields. [0003] Studies have shown that there are only two kinds of solar ultraviolet rays that can pass through the atmos...

Claims

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Application Information

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IPC IPC(8): A61K31/4725A61P17/16A61K8/49A61Q19/08A61Q19/02A61Q17/04
CPCA61K8/4926A61K31/4725A61Q17/04A61Q19/02A61Q19/08
Inventor 白转丽
Owner THE FIRST AFFILIATED HOSPITAL OF XIAN JIAOTONG UNIV
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