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Repair and rejuvenation of tissues using platelet-rich plasma

A technology for platelet-rich plasma and composition, which is used in drug combinations, cosmetic preparations, preparations for skin care, etc., can solve problems such as poor results and cells that cannot be successfully absorbed

Inactive Publication Date: 2016-10-12
小威廉·K·博斯
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the results were poor because the cells could not be successfully absorbed

Method used

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Examples

Experimental program
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Embodiment Construction

[0010] Described herein are various methods for administering platelet-rich plasma (PRP) compositions to a subject for rejuvenation of tissue (eg, skin tissue). The method will generally involve forming microporations in the surface of the skin to enhance absorption of the PRP composition therein. Autologous cells may be added to the PRP composition and then administered to the subject, or the cells may be administered as a separate composition, for example in a layer, before or after administration of the PRP composition . Layering of the compositions can improve their absorption into the skin after microneedling. In addition to PRP administration, layered administration of multiple cell compositions or administration of compositions comprising multiple cell types can also be used to improve skin appearance. For example, skin laxity, discoloration, and dull complexion can be improved using the methods and compositions described herein.

[0011] micro needling

[0012] Mi...

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PUM

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Abstract

This application relates to cosmetic methods for improving skin conditions. The methods generally include the administration of platelet-rich plasma and cultured autologous cells to a subject after a micro-needling procedure has been performed. The platelet-rich plasma and autologous cells can be topically applied to the skin surface or injected into the dermis or subcutaneous tissue. The methods may be used to improve conditions such as acne scars, traumatic scars, hyperpigmentation, fine lines, wrinkles, stretch marks, and hair loss.

Description

field of invention [0001] The present application relates to methods for administering a platelet-rich plasma (PRP) composition to a subject. Specifically, the method may involve topically applying the PRP composition to the skin surface after microneedling, or injecting the PRP composition into subcutaneous or skin tissue. The PRP composition will typically include cultured autologous cells, such as cultured autologous fibroblasts. Conditions such as acne scars, traumatic scars, hyperpigmentation, fine lines, wrinkles, stretch marks, and hair loss can be treated using the composition. Background of the invention [0002] The injection of synthetic materials into the body, and especially into the face, to achieve cosmetic results began at the end of the nineteenth century. For example, paraffin injections to correct facial contour defects were accepted for a brief period in the years leading up to World War I. However, complications and poor long-term outcomes led to the ...

Claims

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Application Information

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IPC IPC(8): A61K45/06A61K35/16A61K35/35A61K35/28A61K35/32A61K35/36A61K35/50A61K35/22A61K9/00A61P17/02A61P17/10A61P17/00A61P17/18A61P17/14
CPCA61K9/0021A61K35/16A61K35/22A61K35/28A61K35/32A61K35/35A61K35/36A61K35/50A61K45/06A61K2300/00A61K8/983A61K9/0014A61K35/19A61K35/33A61K2800/91A61M2037/0061A61P17/00A61P17/02A61P17/10A61P17/14A61P17/18A61Q7/02A61Q19/00A61Q19/02A61Q19/08
Inventor 小威廉·K·博斯
Owner 小威廉·K·博斯
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