Unlock instant, AI-driven research and patent intelligence for your innovation.

Mesoporous silica supported bioglass composite

A technology of mesoporous silica and composite materials, which is applied in the field of materials, can solve the problems of rising product costs, unstable bioglass materials, and restrictions on the practical application of bioglass, and achieve the effect of simple preparation and stable storage

Active Publication Date: 2016-10-26
NANJING TECH UNIV
View PDF4 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The hydrolysis of bioglass materials is the main source of its biological activity, which also leads to the unstable existence of bioglass materials in aqueous solution environments.
Therefore, the current toothpaste with bioglass as the active ingredient is an anhydrous system (generally glycerin system), which not only leads to a substantial increase in product costs, but also limits the practical application of bioglass in many aqueous systems such as oral restorations.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Mesoporous silica supported bioglass composite
  • Mesoporous silica supported bioglass composite
  • Mesoporous silica supported bioglass composite

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] The present invention will be described in detail below with reference to specific embodiments.

[0023] Preparation Examples

[0024] The mesoporous silica-loaded bioglass composite material of the present invention is prepared by the following method:

[0025] 1. Synthesis of mesoporous silica materials: First, dissolve 0.50 g Poloxamer F127 and 1.25 g KCl in 30.0 ml HCl solution with a concentration of 2 M, stir until completely dissolved, and after the solution becomes clear, Add 0.60 g of TMB (mesitylene) to this clear solution, continue stirring for 1 h, and then add 2.23 g of tetraethyl orthosilicate (TEOS) dropwise to the solution, and this solution is vigorously stirred at 15ºC (600-1000 rpm) for 24 hours. After that, it was transferred to the reactor, hydrothermally reacted at 220ºC for 24 hours, filtered and washed, dried in air, and then air-dried. Finally, it was placed in a muffle furnace for calcination at 550ºC for 6 hours, and it was cooled to room te...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
pore sizeaaaaaaaaaa
thicknessaaaaaaaaaa
pore sizeaaaaaaaaaa
Login to View More

Abstract

The invention discloses a mesoporous silica supported bioglass composite. The composite takes a mesoporous silica material as a carrier; bioglass materials are supported in holes of the mesoporous silica material. The composite prepared from mesoporous silica supported bioglass can stably exist in an aqueous phase environment, controllable release can be performed by means of ultrasound, and the activity of the bioglass is not changed.

Description

technical field [0001] The invention belongs to the field of materials, and in particular relates to a composite material of mesoporous silica loaded bioglass. Background technique [0002] Bio-active glass material (bio-active glass), also known as bioglass (bioglass), refers to mainly SiO 2 -Na 2 O-CaO-P 2 O 5 based active glass material. Since it was successfully developed by Professor Hench and others in 1971, its application research in the repair of biological hard tissues (bones, teeth, etc.) and drug carriers has become a research hotspot in biochemistry, materials science, and medicine. In the early days of the invention of bioglass, it was mainly used in the oral cavity, such as the treatment of periodontal disease, root canal filling, and clinical treatment of oral diseases such as the prevention of alveolar atrophy. Today, bioglass for dental medical use has been commercialized and produced, and has gradually expanded from clinical treatment to oral care. Fo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/25A61Q11/00C04B41/85
CPCA61Q11/00A61K8/25C04B41/009C04B41/5022C04B41/85C04B35/14C04B41/4537C04B41/0072
Inventor 万昆明刘建兰李莉
Owner NANJING TECH UNIV