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Compound medicine for treating chronic renal failure

A compound and drug technology, applied in the field of compound drugs for the treatment of chronic renal failure, can solve the problems of complex preparation process, high dosage, difficult quality control and the like

Active Publication Date: 2016-10-26
SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are many types of traditional Chinese medicine formulas, complex preparation process, difficult quality control, large dosage, and unsatisfactory curative effect.

Method used

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  • Compound medicine for treating chronic renal failure
  • Compound medicine for treating chronic renal failure
  • Compound medicine for treating chronic renal failure

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0011] The beneficial effects of the compound drug for treating chronic renal failure of the present invention will be illustrated below through clinical trials, animal experiments and specific examples.

[0012] 1. clinical research

[0013] Diagnostic criteria: Refer to the diagnostic criteria in the "Guiding Principles for Clinical Research of New Chinese Medicines for Chronic Kidney Disease" and "Guiding Principles for Occupational Acute Clinical Research" promulgated by the Ministry of Health, as well as the grading standards for the severity of kidney damage.

[0014] Treatment method: Patients with chronic renal failure were randomly divided into 3 groups.

[0015] The control group took Niaoduqing Granules: 1 bag each time, 3 times a day; 4 weeks was a course of treatment.

[0016] Treatment group 1 and treatment group 2 took the medicines of the high-dose group and the low-dose group of the present invention respectively. Efficacy criteria: Refer to the efficacy cr...

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PUM

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Abstract

The invention relates to compound medicine for treating chronic renal failure. The compound medicine comprises, by weight, 15-45 parts of astragalus membranaceus, 15-45 parts of codonopsis pilosula, 5-15 parts of rhizoma smilacis glabrae, 10-30 parts of red peony roots, 15-45 parts of raw oysters, 10-30 parts of centella asiatica and 5-15 parts of raw rhubarb. The effect of tonifying kidney, promoting blood circulation, removing blood stasis, promoting dieresis and resolving phlegm is achieved. The compound medicine is used for treating main clinic symptoms such as kidney deficiency type edema, soreness and weakness of waist and knees, nausea and vomiting, anorexia, ozostomia, polyuria or oliguria, fatigue, headache, dysphoria, bleeding from five sense organs or subcutaneous tissues, lusterless complexion and pellagra. The compound medicine has the advantages of good effect, less medicinal flavor, high biological utilization rate, safety, reliability and the like.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines and relates to a compound medicine for treating chronic renal failure. Background technique [0002] Chronic renal failure (CRF) refers to a series of symptoms or clinical syndromes of metabolic disorders in patients with various primary diseases or secondary chronic kidney disease with progressive renal impairment. The total prevalence of chronic kidney disease in my country is 10.8%. According to data, chronic kidney disease has become a refractory disease that seriously threatens human health worldwide after cardiovascular and cerebrovascular diseases, tumors, and diabetes. People with chronic kidney disease are 100 times more likely to die prematurely than people without chronic kidney disease. Although renal dialysis and renal transplantation can greatly improve the survival rate of some end-stage patients, they impose a heavy economic burden on society and families, and are not ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/90A61K36/896A61P13/12A61K35/618
CPCA61K9/0095A61K35/618A61K36/23A61K36/344A61K36/481A61K36/65A61K36/708A61K36/71A61K36/896A61K36/90A61K2300/00
Inventor 张诏沈会王萍陶汉华张萌孙琳
Owner SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE