A pharmaceutical composition for treating radiation-induced oral mucositis and its preparation method
A technology for oral mucositis and radioactivity, which is applied in the field of medicine, can solve problems such as poor results, and achieve the effects of low cost, wide sources, and simple production methods
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Embodiment 1
[0048] Example 1: Scrophulariaceae, Ganoderma lucidum, and Shegan were crushed into coarse particles, and 15g of Scrophulariaceae, 10g of Ganoderma lucidum, 10g of Shegan, and 10g of silkworm excrement were weighed respectively, and 10 times the volume of distilled water was added, soaked for 1h, heated and refluxed twice, 2h / Once, the reflux extracts were combined, rotary evaporated, and dried under reduced pressure at 50°C, and finally the dried extract was pulverized and passed through a 100-mesh sieve. The extracts were uniformly mixed, and 5 g of Gallus gallis (passed through a 100-mesh sieve), 100 mg of chlorogenic acid, 11.5 g of maltodextrin, and 0.5 g of stevioside were added, and mixed again. Add 90% ethanol to make soft material, pass through a 16-mesh sieve to granulate, dry in an oven at 60°C, and pass the dried granules through a 16-mesh sieve for granulation.
Embodiment 2
[0049] Example 2: Scrophulariaceae, Ganoderma lucidum, and Shegan were crushed into coarse particles, and 9g of Scrophulariaceae, 6g of Ganoderma lucidum, 3g of Shegan, and 5g of silkworm excrement were weighed respectively, and 10 times the volume of distilled water was added, soaked for 1h, heated and refluxed twice, 2h / Once, the reflux extracts were combined, rotary evaporated, and dried under reduced pressure at 50°C, and finally the dried extract was pulverized and passed through a 100-mesh sieve. The extracts were uniformly mixed, and 3 g of Gallus gallis (passed through a 100-mesh sieve), 80 mg of chlorogenic acid, 11.5 g of maltodextrin, and 0.5 g of stevioside were added, and mixed again. Add 90% ethanol to make soft material, pass through a 16-mesh sieve to granulate, dry in an oven at 60°C, and pass the dried granules through a 16-mesh sieve for granulation.
Embodiment 3
[0050] Example 3: Scrophulariaceae, Ganoderma lucidum, and Shegan were crushed into coarse particles, and 15g of Scrophulariaceae, 10g of Ganoderma lucidum, 10g of Shegan, and 10g of silkworm excrement were weighed, and 10 times the volume of distilled water was added, soaked for 1h, heated and refluxed twice, 2h / Once, the reflux extracts were combined, rotary evaporated, and dried under reduced pressure at 50°C, and finally the dried extract was pulverized and passed through a 100-mesh sieve. The extracts were uniformly mixed, and 5 g of Gallus gallis (passed through a 100-mesh sieve), 120 mg of chlorogenic acid, 12 g of maltodextrin, and 0.6 g of stevioside were added, and mixed again. Add 90% ethanol to make soft material, pass through a 16-mesh sieve to granulate, dry in an oven at 60°C, and pass the dried granules through a 16-mesh sieve for granulation.
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