Rhizoma fagopyri dibotryis extract, preparation methods and applications of rhizoma fagopyri dibotryis extract and skin external-use preparation containing rhizoma fagopyri dibotryis extract

A skin external preparation, the technology of golden buckwheat, applied in the field of golden buckwheat extract, preparation, application and skin external preparations containing it, can solve the problems of poor anti-aging and whitening effect and low safety, and achieve good market prospects Effect

Inactive Publication Date: 2017-01-04
JALA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The technical problem to be solved by the present invention is to provide golden buckwheat extract, preparation method, application and skin external preparation containing it in order to overcome the shortcomings of cosmetics in the prior art such as poor anti-aging and whitening effects and low safety

Method used

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  • Rhizoma fagopyri dibotryis extract, preparation methods and applications of rhizoma fagopyri dibotryis extract and skin external-use preparation containing rhizoma fagopyri dibotryis extract
  • Rhizoma fagopyri dibotryis extract, preparation methods and applications of rhizoma fagopyri dibotryis extract and skin external-use preparation containing rhizoma fagopyri dibotryis extract
  • Rhizoma fagopyri dibotryis extract, preparation methods and applications of rhizoma fagopyri dibotryis extract and skin external-use preparation containing rhizoma fagopyri dibotryis extract

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Experimental program
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Effect test

Embodiment 1

[0037] Embodiment 1 is that the ethanol aqueous solution of 50% is extraction solvent (method 1) with volume concentration

[0038] 20 g of golden buckwheat dry powder (the particle size of golden buckwheat powder is 20 orders), under room temperature (25 ℃) is 50% ethanol aqueous solution 200ml ultrasonic extraction 2 times, each time 30min (power 500W), get filtrate and merge, reduce Press (50° C.) to recover the solvent to dryness, take an appropriate amount of extract, add DMSO (dimethyl sulfoxide) to prepare a 0.05 mg / ml solution for later use, and measure its free radical scavenging effect, and its free radical scavenging rate is 7%.

Embodiment 2

[0039] Embodiment 2 is that the ethanol aqueous solution of 60% is extraction solvent (method 1) with volume concentration

[0040] 20 g of golden buckwheat dry powder (the particle size of golden buckwheat powder is 30 orders), under room temperature (25 ℃), be 60% ethanol aqueous solution 200ml ultrasonic extraction 2 times, each 30min (power 500W), take filtrate and merge, reduce Press (50° C.) to recover the solvent to dryness, take an appropriate amount of extract, add DMSO (dimethyl sulfoxide) to prepare a 0.05 mg / ml solution for later use, and measure its free radical scavenging effect, and its free radical scavenging rate is 23%.

Embodiment 3

[0041] Embodiment 3 is that the ethanol aqueous solution of 70% is extraction solvent (method 1) with volume concentration

[0042] 20 g of golden buckwheat dry powder (the particle size of golden buckwheat powder is 40 orders), under room temperature (25 ℃), be 70% ethanol aqueous solution 200ml ultrasonic extraction 2 times, each time 30min (power 500W), get filtrate and merge, reduce Press (50° C.) to recover the solvent to dryness, take an appropriate amount of extract, add DMSO (dimethyl sulfoxide) to prepare a 0.05 mg / ml solution for later use, and measure its free radical scavenging effect, and its free radical scavenging rate is 51%.

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Abstract

The invention discloses a rhizoma fagopyri dibotryis extract, preparation methods and applications of the rhizoma fagopyri dibotryis extract and a skin external-use preparation containing the rhizoma fagopyri dibotryis extract. The preparation method I of the rhizoma fagopyri dibotryis extract comprises the following steps: 1, extracting a mixture formed by fagopyrum dibotrys powder and ethanol aqueous solution with the volume concentration being 50-80% for 0.5-5 h at 10-35 DEG C, carrying out solid-liquid separation to obtain a filtrate, and removing a solvent from the filtrate, thus obtaining a rhizoma fagopyri dibotryis crude extract, wherein the mass-to-volume ratio of the fagopyrum dibotrys powder to the ethanol aqueous solution is 1:8-1:15 g / mL; The preparation method II of the rhizoma fagopyri dibotryis extract comprises the following steps: loading the rhizoma fagopyri dibotryis crude extract obtained in the method I to a macroporous resin packing column, carrying out elution by adopting a solvent I, a solvent II and a solvent III sequentially, respectively collecting the eluants, and removing the solvents to obtain a solvent elution part A, a solvent elution part B and a solvent elution part C. The rhizoma fagopyri dibotryis extract has the good efficacies of whitening the skin, resisting ageing and resisting oxidation, thus having a good market prospect.

Description

technical field [0001] The present invention relates to golden buckwheat extract, preparation method, application and skin external preparation containing it. Background technique [0002] In 1956, Harman proposed the theory of free radical aging [Harman, D. Aging: A theory based on free radical and radiation chemistry. J. Gerontol. 1956, 11: 289-300.], thinking that excessive free radicals are the cause of biological aging important reason. According to this theory, excess active oxygen free radicals in the body react with unsaturated fatty acids to produce substances such as malondialdehyde, and malondialdehyde will react with proteins on the cell membrane to produce brown pigment, which precipitates on the skin and becomes various stains. Excessive free radicals can also cause cross-linking and denaturation of collagen fibers and elastic fibers in the skin, making them brittle and losing elasticity. When the skin is insufficiently hydrated, it is easy to break the elasti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/02A61Q19/08A61K36/70A61P17/00A61P17/18
Inventor 金家宏
Owner JALA GROUP CORPORATION
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