AIDS Infected Cell Separator

A technology for infecting cells and separators, applied in suction devices, blood circulation treatment, etc., can solve the problems of high price, drug-induced liver injury, lipid metabolism disorder, etc., and achieve the effect of high cost and no drug side effects

A technology for infecting cells and separators, applied in suction devices, blood circulation treatment, etc., can solve the problems of high price, drug-induced liver injury, lipid metabolism disorder, etc., and achieve the effect of high cost and no drug side effects

CN106267410BActive Publication Date: 2019-03-08翁炳焕 +1
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  • AIDS Infected Cell Separator
  • AIDS Infected Cell Separator
  • AIDS Infected Cell Separator

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0012] figure 1 It is an application schematic diagram of the AIDS-infected cell separator proposed according to the present invention.

[0013] figure 2 It is a schematic diagram of the internal structure of the AIDS-infected cell separator.

[0014] figure 1Among them, one end of the arterial blood line (1) communicates with the arterial blood vessel, and the other end communicates with the inlet (4) of the lumen (6) of the separator (7), with a flow valve (2) and a sample inlet ( 3), the tube wall (5) of the lumen (6) has many micropores that can pass through various single blood cells and chemical components but cannot pass through the large-volume cells formed by the adhesion of 2 or more cells, the lumen (6) These micropores of the tube wall (5) communicate with the external cavity (8), the external cavity (8) communicates with one end of the venous blood line tube (9), and the other end of the venous blood line tube (9) communicates with the venous blood vessel, Th...

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Abstract

The invention relates to an AIDS-infected cell separator in the field of biomedicine, which is characterized in that it is made of a high-biocompatibility material that can pass through a single blood cell and chemical components but cannot pass through two or more large-volume cells that are bonded together. 150~250μm, 50~150μm, 15~40μm, 8~15μm, 5~8μm, 3~5μm, 1~2μm, correspondingly calibrated as type I~VII cell separators, simultaneously prepare HIVgp120 and CD4 antibodies, HIV infection The gp120 on the cell surface can bind other CD4+ cells by itself or under the action of gp120 antibody or CD4 antibody to form large multinucleated giant cells. Type I-II separators are used to separate super-large fungi, spirochetes, and tumor cells. HIV-infected large-volume multinucleated giant cells, multicellular aggregates, CD4+ cells susceptible to HIV infection, and AIDS-infected cells are separated and cleared in the extracorporeal circulation composed of separators and other components.

Description

technical field [0001] The invention relates to an AIDS-infected cell separator, which is mainly used in the field of biomedicine to filter and remove CD4+ cells infected by HIV in the blood of AIDS patients, so as to achieve the purpose of treating AIDS. Background technique [0002] AIDS is an infectious disease caused by human immunodeficiency virus (Human Immunodeficiency Virus, HIV). So far, 208 countries and regions in the world have been seriously threatened by AIDS. About 40 million people have been infected with AIDS, and the death toll has exceeded 20 million. About 6,000 people become AIDS-infected people every day, and more than 300 people die every day. on AIDS. HIV-infected people in China are in a period of rapid growth, and the number has far exceeded 1 million at present. AIDS has become another major infectious disease facing mankind after tumors, cardiovascular and cerebrovascular diseases, tuberculosis, and diabetes, and has become a serious public heal...

Claims

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Application Information

Patent Timeline
08 Mar 2019
Publication
CN106267410B
IPC
A61M1/36
CPC
A61M1/3692; A61M1/3627
Inventors
翁炳焕; 李兰娟