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hiv phagocytosis

A technology of phagocytic cells and organelles, applied in the field of biomedicine, can solve the problems of lack of immunity to kill HIV, large toxic and side effects, and poor drug efficacy.

Active Publication Date: 2019-01-22
ATTACHED OBSTETRICS & GYNECOLOGY OSPITAL MEDICALCOLLEGE ZHEJIANG UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The human body lacks the immunity to kill HIV, and the drugs used in the body have poor curative effect and severe side effects. AIDS is a worldwide problem that cannot be overcome for a long time.

Method used

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Examples

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Embodiment Construction

[0015] figure 1 It is an application schematic diagram of the HIV phagocytosis organelle proposed according to the present invention.

[0016] figure 2 It is the internal structure diagram of the plasma separator proposed according to the present invention.

[0017] image 3 It is the internal structure diagram of the HIV phagocytic organelle proposed according to the present invention.

[0018] figure 1 Among them, one end of the arterial blood line tube (1) is connected with the arterial blood vessel, and the other end is connected with the plasma separator (4) through the heparin pump (2) and the blood pump (3), and the plasma separator (4) is connected through the plasma pump (6) ) and the circulation line (7) are connected with two parallel organelles (8) and organelles (9), and then connected with the circulation line (10) and the venous line (5) in turn, and the other of the venous line (5) One end is connected to the vein blood vessel.

[0019] figure 2 Among th...

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Abstract

The invention relates to an HIV phagocytosis organelle and relates to the field of biomedicine. The organelle is characterized in that CD14 cells are separated through the magnetic activated cell sorting method, then a hybridoma macrophage cell line which keeps the characteristic of original macrophage and can grow infinitely is prepared, a clone high in HIV phagocytosis is selected for amplification culture and preservation, the prepared hybridoma macrophage cell line is wrapped by a high-biocompatibility material to prepare the organelle which can prevent cells, cell debris or even HIV from being filtered out and can provide a place for the cell line to phagocytose HIV, the organelle and a plasma separator form extracorporeal circulation, after the separated plasma is filtered out by the organelle, HIV in the plasma is phagocytosed and removed by the hybridoma macrophage cell line, generated anti-infection macrophage factors are transfused back into a body along with the plasma, accordingly a new AIDS hybridoma technique extracorporeal therapy which can be used for removing HIV and supplementing required macrophage factors is implemented, and compared with a traditional therapy which is used for killing HIV in the body and is difficult to implement, the organelle is more feasible and free of toxic and side effects.

Description

technical field [0001] The invention relates to HIV phagocytosis cell organelles in the field of biomedicine, which mainly prepares HIV sensitive cells through artificial industry, and is used to phagocytize free HIV in plasma in vitro to achieve the purpose of treating AIDS. Background technique [0002] AIDS is an infectious disease caused by human immunodeficiency virus (Human Immunodeficiency Virus, HIV). So far, 208 countries and regions in the world have been seriously threatened by AIDS. About 40 million people have been infected with AIDS, and the death toll has exceeded 20 million. About 6,000 people become AIDS-infected people every day, and more than 300 people die every day. on AIDS. HIV-infected people in China are in a period of rapid growth, and the number has far exceeded 1 million at present. AIDS has become another major infectious disease facing mankind after tumors, cardiovascular and cerebrovascular diseases, tuberculosis, and diabetes, and has become ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M1/36
CPCA61M1/3692
Inventor 翁炳焕李兰娟潘小平虞晓鹏严恺
Owner ATTACHED OBSTETRICS & GYNECOLOGY OSPITAL MEDICALCOLLEGE ZHEJIANG UNIV
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