Intermediate infrared graphene plasmon polariton biochemical sensor

Abstract

The invention discloses an intermediate infrared graphene plasmon polariton biochemical sensor. The intermediate infrared graphene plasmon polariton biochemical sensor comprises an intermediate infrared broad band optical source, a first intermediate infrared lens, a graphene plasmon polariton sensing unit and a second intermediate infrared lens; the graphene plasmon polariton sensing unit comprises a doped silicon substrate, a first grating coupling area, a second grating coupling area, a sensing area, and a graphene layer, wherein the graphene layer covers the first grating coupling area, the second grating coupling area and the sensing area; an intermediate infrared light wave emitted by the broad band optical source is focused in the first grating coupling area through the first intermediate infrared lens so as to be coupled with a graphene plasmon polariton, the produced intermediate infrared graphene plasmon polariton reaches the sensing area through the graphene layer, repeatedly reacts with a biological sample in the sensing area, reaches the second grating coupling area through the graphene layer, is scattered to the far field, and is focused to a fourier infrared spectrometer through the second intermediate infrared lens to implement spectral measurement and analysis. The intermediate infrared graphene plasmon polariton repeatedly reacts with the biological sample in the sensing area, and the detection sensitivity of biomolecules is improved.

Description

technical field [0001] The invention relates to the field of optical sensing, in particular to a mid-infrared graphene plasmon biochemical sensor. Background technique [0002] The mid-infrared band (3-30 microns) is specially used in biochemical sensing. This band covers the vibrational energy levels of molecules and can be used to identify and analyze the basic biochemical structural units of life, such as proteins, fats, and DNA. Mid-infrared absorption spectroscopy technology can obtain the biochemical information of substances non-invasively and without labels through the fingerprint absorption of molecular resonance. However, due to the mismatch between the size of biochemical molecules (usually less than 10 nanometers) and the mid-infrared wavelength, the vibrational absorption of molecules is very weak, which is very unfavorable for the detection of nanoscale molecules. In order to overcome the limitation of weak absorption, local resonance Metal nanostructures are ...

AI Technical Summary

Problems solved by technology

However, due to the mismatch between the size of biochemical molecules (usually less than 10 nanometers) and the mid-infrared wavelength, the vibrational absorption of molecules is very weak, which is very unfavorable for the detection of nanoscale molecules. In order to overcome the limitation of weak absorption, local resonance Metal nanostructures are applied to molecular detection to enhance the sensitivity of molecular detection

Although metal nanoresonance can enhance the detection sensitivity of nanoscale molecules, metal nanoresonance technology is still limited by relatively weak optical enhancement and Non-tunable Narrow Band Spectrum

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