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Composition capable of enhancing immunity and production method of composition

A technology for enhancing immunity and production methods, applied in the fields of food, health food and pharmaceuticals, can solve the problems of increased cost and process complexity, increased production environment risk level, unsuitable for industrialized production, etc., and achieves low production process difficulty and enhanced Immunity, mild medicinal effect

Inactive Publication Date: 2017-05-10
华瑞(福建)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The black ginseng processed by the traditional nine-steaming and nine-exposure process often has a low content of rare ginsenosides; as an improvement, the Chinese patent application number 201510317562.3 discloses a method for preparing black ginseng with a high content of ginsenosides. The content of the active substance ginsenoside has been improved to a certain extent, but the process needs multiple ultrasonic treatments, which is relatively cumbersome and not suitable for industrial production; and the Chinese patent application number 200780016985.5 discloses black ginseng, black ginseng concentrate and black ginseng fruit The production method, the introduction of ethanol, not only increases the cost and complexity of the process, but also increases the risk level of the production environment

Method used

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  • Composition capable of enhancing immunity and production method of composition
  • Composition capable of enhancing immunity and production method of composition
  • Composition capable of enhancing immunity and production method of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Step 1: Preparation of black ginseng

[0051] Control the water content of ginseng at (20±2)% by humidifying, then steam at 105°C for 1 hour, bake at 60°C until the water content is (20±2)%, then steam at 105°C for 1 hour, and bake at 60°C until it contains The water content is (20±2)%, repeated 10 times, the color gradually deepens, and the 10th time is dried to a water content of 10%, which is the finished product of black ginseng;

[0052] Step 2: Ganoderma lucidum extract (Ganoderma lucidum extract whose phospholipid polysaccharide content accounts for more than 10% of the total mass of the Ganoderma lucidum extract), Astragalus (astragaloside IV whose content accounts for more than 0.1% of the mass of traditional Chinese medicine decoction pieces) and the black tea prepared in step 1 The ginseng was pulverized respectively and passed through a 100-mesh sieve to obtain powdered ganoderma extract, astragalus powder and black ginseng powder;

[0053] Step 3: Weigh 25...

Embodiment 2

[0068] Example 2 Experimental Animals and Detection Conditions

[0069] 1 Materials and methods

[0070] 1.1 Experimental animals and testing conditions

[0071] Experimental SD rats, clean grade, weighing 60-80g. Detect environmental conditions, barrier environment, temperature 20°C-23°C, relative humidity range 50%-70%. The experimental animals were acclimatized in the animal room environment for 3 days before the experiment.

[0072] 1.2 Dose Design

[0073] The recommended dosage of the health food of the present invention (the formula is the composition or capsule in Implementation 1) is 2.4g / 60kg·day. The experiment set up three dosage groups and a negative control group. The low, medium and high dosages were 1.0g / kg, 2.0g / kg and 4.0g / kg body weight respectively, equivalent to 25 times, 50 times and 100 times the human recommended dosage. times. In each dose group of the experiment, the samples were evenly mixed into the basal feed according to 10% of the body weig...

Embodiment 3

[0080] Example 3 Cellular immune function test

[0081] 1. Test materials and methods

[0082] Experimental Materials

[0083] The capsules prepared in Example 1 and the capsules prepared in Comparative Example 4.

[0084] The experimental animals used were ICR mice, clean grade, female, with a body weight of 20g-22g. Detect environmental conditions, barrier environment, temperature 20°C-24°C, relative humidity 40%-70%. The animals were acclimatized in the animal room environment for 4 days before the experiment.

[0085] 1.2 Dose Design

[0086] Three dose groups and negative control group (distilled water) were set up in the experiment. Embodiment 3 and comparative example 5 samples low, medium and high three dosages are respectively 0.25g / kg, 0.5g / kg, 1.5g / kg body weight, equivalent to 5 times, 10 times and 30 times of people's recommended dose (human The recommended amount is 3.0g / 60kg per day) The three dose groups respectively weighed 1.5g, 3.0g and 6.0g of the tes...

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Abstract

The invention provides composition capable of enhancing immunity. The composition is prepared from a ganoderma lucidum extract, radix astragai and black ginseng in a mass ratio being (0.1-0.2):(0.2-0.5):1, wherein the black ginseng has rare ginsenoside content being 20% of black ginseng mass or above. The invention further provides a production method of the composition. The production method comprises steps as follows: the black ginseng is prepared by humidifying ginseng, steaming ginseng at the steaming temperature of 104-106 DEG C and drying ginseng 9-11 times; the ganoderma lucidum extract, the radix astragai and the black ginseng are crushed and sieved; sieved powdery ganoderma lucidum extract, radix astragai and black ginseng are mixed in a mass ratio being (0.1-0.2):(0.2-0.5):1. The composition has high rare ginsenoside content and can significantly enhance immunity, and meanwhile, the production process is simple, has high condition controllability and is suitable for mass production.

Description

technical field [0001] The invention relates to the fields of food, health food and medicine, in particular to a composition for enhancing immunity and a production method thereof. Background technique [0002] Immunity refers to the ability of the body to resist external invasion and maintain the stability of the internal environment. The air is full of all kinds of microorganisms: bacteria, viruses, mycoplasma, chlamydia, fungi, etc. In the case of insufficient human immunity, they can all become pathogens. Although the human body will produce corresponding antibodies against different pathogens to resist re-infection, antibodies are specific and time-limited. Can not resist other virus infection. [0003] Nowadays, people with low immunity generally exist in the world, and the number of people is large. With the enhancement of people's health awareness, the demand for products that maintain the normal immune function of the human body still exists in the health food ma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61P37/04A23L33/10
CPCA61K36/258A23V2002/00A61K36/074A61K36/481A61K2300/00A23V2200/324A23V2250/21A23V2250/208
Inventor 胡堃林广勤许向前
Owner 华瑞(福建)生物科技有限公司
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