Unlock instant, AI-driven research and patent intelligence for your innovation.

Tea polyphenol extract dropping pill and preparation method thereof

A technology for the preparation of dripping pills and tea polyphenols, which is applied in the directions of pill delivery, drug combination, pharmaceutical formulation, etc., can solve problems such as low bioavailability, and achieve the effect of fast forming and uniform shape

Active Publication Date: 2017-05-10
GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to its easy degradation in the intestinal tract, resulting in low bioavailability

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Tea polyphenol extract dropping pill and preparation method thereof
  • Tea polyphenol extract dropping pill and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] According to the mass ratio of tea polyphenols: PEG6000: stearic acid = 1:4.6:0.4, heat to 75°C. After mixing well, adjust the temperature of the condensate to 10°C and the temperature of the nozzle to 50°C. The control dripping speed is 360 drops per minute. The content of epigallocatechin gallate in the tea polyphenol is 90%.

Embodiment 2

[0029] According to the mass ratio of tea polyphenols: PEG6000: stearic acid = 1:4.7:0.3, heat to 80°C, after fully mixing, adjust the temperature of the condensate to 10°C, and the temperature of the nozzle to 50°C. The control dripping speed is 350 drops per minute. The content of epigallocatechin gallate in the tea polyphenol is 90%.

Embodiment 3

[0031] According to the mass ratio of tea polyphenols: PEG6000: stearic acid = 1:4.8:0.2, heat to 85°C, after fully mixing, adjust the temperature of the condensate to 5°C, and the temperature of the nozzle to 55°C. The control dripping speed is 380 drops per minute. The content of epigallocatechin gallate in the tea polyphenol is 90%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a tea polyphenol extract dropping pill and a preparation method of the tea polyphenol extract dropping pill. The dropping pill is prepared from tea polyphenol, PEG and stearic acid. The preparation method comprises the following steps: (1) mixing tea polyphenol, PEG 6000 and stearic acid; (2) heating the mixed solution so that the complete dissolving state is achieved; and (3) dropwise adding the dissolved solution into liquor condensate through a dropping pipette at the speed of 350-380 drops per minute, thus forming the dropping pill. With the adoption of the preparation method, the tea polyphenol extract dropping pill is rapid in forming and uniform in shape.

Description

technical field [0001] The invention relates to a preparation method of a drop pill, in particular to a tea polyphenol extract drop pill and a preparation method thereof. Background technique [0002] Epigallocatechin gallate (EGCG) is the main component of green tea polyphenols, and also the main component of green tea catechins, including EGCG, EGC, ECG, EC, GCG and so on. Studies have shown that EGCG has anti-free radical DNA damage, anti-radiation and ultraviolet rays, prevents oil peroxidation, reduces the content of low-density lipoprotein, ultra-low-density lipoprotein and triglyceride in serum, interferes with the signal transmission required for cancer cell survival, Inhibit dietary carcinogens, work with other enzymes and antioxidants in the intestines, liver, and lungs to block the activity of certain carcinogens, scavenge free radicals, resist the effects of pollution, sun exposure and smoking, and prevent skin aging and inflammation wrinkle. However, its bioav...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/82A61K31/353A61K9/20A61K47/10A61K47/12A61P17/18A61P35/00A61P39/06
CPCA61K9/2031A61K31/353A61K36/82
Inventor 蒋琳兰曾午娟
Owner GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND