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Compound licorice root lollipop for treating radiation-induced oral mucositis

A technology of oral mucositis and compound licorice, which is applied in the field of medicinal lollipops, can solve the problems of choking patients, insecurity, aspiration, etc., and achieve the effect of reducing dry mouth and pain

Inactive Publication Date: 2017-05-24
JINHUA MUNICIPAL CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The existing technology is to make the drug for the treatment of radioactive oral mucositis into ice cubes, but the watery drug after the ice melts is easy to enter the pharynx, causing aspiration and choking the patient, which is unsafe.

Method used

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  • Compound licorice root lollipop for treating radiation-induced oral mucositis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A preparation method of compound licorice lollipop for treating radioactive oral mucositis of the present invention, the specific preparation method is as follows:

[0029] (1) Select 10-30g of raw licorice, add 250-750ml of water to soak for 30min, then decoct on low heat for 10min, filter the juice to remove slag, cool naturally to make about 125-375ml for later use. Take 125-375ml of licorice liquid, add 2.5-7.5g of Biafine, 40-1.2 million units of gentamicin, 0.05-0.15g of lidocaine, 10-30g of sugarcane juice, 20-60g of pectin, 5- 15g and corn syrup 10-30g form a mixture;

[0030] (2) Pour the mixture obtained in step (1) into a lollipop mold and press it into a 0.5cm thick, 2cm wide oval sugar structure, and insert a stick for condensation drying;

[0031] (3) A compound licorice lollipop for treating radiation-induced oral mucositis is made after condensation drying.

Embodiment 2

[0033] A preparation method of compound licorice lollipop for treating radioactive oral mucositis of the present invention, the specific preparation method is as follows:

[0034] (1) Select 10-30g of raw licorice, add 250-750ml of water to soak for 30min, then decoct on low heat for 10min, filter the juice to remove slag, cool naturally to make about 125-375ml for later use. Take 125-375ml of licorice liquid, add 2.5-7.5g of Biafine, 40-1.2 million units of gentamicin, 0.05-0.15g of lidocaine, 10-30g of water chestnut juice, 20-60g of pectin, 5- 15g and xylitol 10-30g form a mixture;

[0035] (2) Pour the mixture obtained in step (1) into a lollipop mold and press it into a 0.5cm thick, 2cm wide oval sugar structure, and insert a stick for condensation drying;

[0036] (3) A compound licorice lollipop for treating radiation-induced oral mucositis is made after condensation drying.

[0037]The preparation method adopts a low-sugar formula, which is suitable for diabetic pati...

Embodiment 3

[0039] A preparation method of compound licorice lollipop for treating radioactive oral mucositis of the present invention, the specific preparation method is as follows:

[0040] (1) Select 10g of raw licorice, add 250ml of water to soak for 30min, then decoct on low heat for 10min, filter the juice to remove residue, cool naturally to make about 125ml for later use. Take 125ml of licorice liquid, add 2.5g of Biafine, 400,000 units of gentamicin, 0.05g of lidocaine, 10g of sugarcane juice, 20g of pectin, 5g of caramel and 10g of corn syrup to form a mixture;

[0041] (2) Pour the mixture obtained in step (1) into a lollipop mold and press it into a 0.5cm thick, 2cm wide oval sugar structure, and insert a stick for condensation drying;

[0042] (3) A compound licorice lollipop for treating radiation-induced oral mucositis is made after condensation drying.

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Abstract

The invention provides compound licorice root lollipop for treating radiation-induced oral mucositis. The lollipop is prepared by mixing and proportioning a plurality of medicinal materials, including 125-375ml of licorice extract, 2.5-7.5g of biafine, 40-120 million units of gentamicin, 0.05-0.15g of lidocaine, and a proper amount of auxiliaries and a solidifying agent for nourishing yin, moistening dryness and promoting generation of body fluid. The compound licorice root lollipop can be used for effectively treating radiation-induced oral mucositis, and reducing symptoms of dry mouth, oropharynx pain, mucosa reaction and the like. By adopting a lollipop preparation mode, medicinal materials can be slowly molten in a patient, cannot easily choke the patient, can be taken out from the mouth at any time when the patient needs to reduce the taking amount before eating or swallowing training, can be taken for multiple times, and is convenient for use.

Description

technical field [0001] The invention relates to a medicinal lollipop, in particular to a compound licorice lollipop for treating radioactive oral mucositis. Background technique [0002] Nasopharyngeal carcinoma is one of the most common clinical malignant tumors, accounting for more than 70% of head and neck tumors. Radiation therapy is the main method for the treatment of nasopharyngeal carcinoma, and its effect is definite. With the continuous improvement of radiotherapy and comprehensive treatment techniques, the 5-year survival rate of nasopharyngeal carcinoma is 76.6%. The most common and most important side effects during radiotherapy for nasopharyngeal carcinoma—ulcer and pain caused by radiation oral mucositis directly affect the degree and intensity of mouth opening training, the continuous effect of radiation and the nutritional deficiency caused by difficulty in eating affect the Mucosa repair is hindered, and delayed healing leads to fibrous tissue hyperplasia ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/484A61K9/00A61P1/02A61P11/04A23G3/48A23G3/36A61K31/133A61K31/7036A61K31/167
CPCA23G3/364A23G3/48A23V2002/00A61K9/0056A61K31/133A61K31/167A61K31/7036A61K36/484A61K47/46A61K2300/00A23V2200/314A23V2200/32A23V2250/5072A23V2250/6422
Inventor 陈巧鸽
Owner JINHUA MUNICIPAL CENT HOSPITAL
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