Vancomycin production wastewater treatment method

Abstract

The present invention relates to a vancomycin production wastewater treatment method, which comprises: (1) carrying out coagulation precipitation treatment on vancomycin production wastewater, and filtering to remove precipitate; (2) carrying out anaerobic biochemical treatment on the effluent obtained in the step (1), and pouring Pseudomonas stutzeri FSTB-5; and (3) carrying out aerobic biochemical treatment on the effluent obtained in the step (2), and pouring a COD removing denitrogenation bacterial agent, wherein the COD removing denitrogenation bacterial agent comprises at least one selected from Pseudomonas stutzeri FSTB-5, Paracoccus denitrificans DN-3 and Methylobacterium SDN-3, at least one selected from Arthrobacter FDN-1 and Flavobacterium aquatile FDN-2, and at least one selected from Kocuria palustris FSDN-A and Staphylococcus cohnii FSDN-C. According to the present invention, the coagulation precipitation-anaerobic biochemical treatment-aerobic biochemical treatment combination treatment process is used, the specific COD removing bacterial agent is poured into the anaerobic unit, and the specific COD removing denitrogenation bacterial agent is poured into the aerobic unit, such that the efficient removal of the COD and the total nitrogen from wastewater is achieved, and the treatment method has characteristics of simple process, high treatment efficiency, low treatment cost, and the like.

Description

technical field

[0001] The invention belongs to the technical field of waste water treatment, and in particular relates to a treatment method for waste water produced by vancomycin. Background technique

[0002] Antibiotics are a great discovery in human history. They have been widely used in medical and other fields, effectively protecting human health. However, during the production and application of antibiotics, a large amount of refractory organic wastewater containing antibiotics will be produced. Vancomycin is a glycopeptide antibiotic that interferes with cell wall synthesis by interfering with a key component in cell wall structure, inhibiting the production of phospholipids and peptides in the cell wall. Vancomycin production wastewater mainly comes from the main processes of macroporous adsorption resin elution, decolorization, gelation, etc., and is concentrated by reverse osmosis.

[0003] The wastewater contains bacteria that produce vancomycin, acetone, etha...

Examples

Embodiment 1

[0037] The quality of wastewater produced by a vancomycin production process in a factory is: COD (Cr method, the same below) is 110,000 mg / L, pH is 4.0, and ammonia nitrogen is 500 mg / L.

[0038] Adopt the method of the present invention to treat wastewater, first add polyacrylamide, the dosage is 10mg / L, then add polyferric sulfate, the dosage is 60mg / L, filter to remove sediment, and use intermittent centrifuge to filter , the rotating speed is controlled at 3000rpm, and the centrifugation time is 5min. The concentration of suspended solids in the coagulation effluent drops below 500mg / L, and the pH value is 7.8. The coagulation effluent enters the internal circulation anaerobic reactor (IC), and at the same time, the concentrated bacterial solution of Pseudomonas stutzeri FSTB-5 obtained from the above culture is added at 0.3% of the volume of the treated wastewater per hour. The operating conditions of the anaerobic biochemical treatment are: the hydraulic retention time...

Embodiment 2

[0040] The quality of wastewater produced by a vancomycin production process in a factory is: COD (Cr method, the same below) is 120,000 mg / L, pH is 3.5, and ammonia nitrogen is 600 g / L.

[0041] Adopt the method of the present invention to treat the waste water, first add polyacrylamide, the dosage is 5mg / L, then add ferric chloride, the dosage is 100mg / L, filter and remove the precipitate, and use a batch centrifuge to carry out For filtration, the rotating speed is controlled at 3000rpm, and the centrifugation time is 5min. The concentration of suspended solids in the coagulation effluent drops below 500mg / L, and the pH value is 7.5. The coagulation effluent enters the fully mixed anaerobic reactor, and at the same time, the concentrated bacterial solution of Pseudomonas stutzeri FSTB-5 obtained from the above culture is added at 0.5% of the volume of the treated wastewater per hour. The operating conditions of the anaerobic biochemical treatment are: the hydraulic retenti...

Embodiment 3

[0043] The quality of wastewater produced by a vancomycin production process in a factory is: COD (Cr method, the same below) is 120,000 mg / L, pH is 3.5, and ammonia nitrogen is 600 g / L.

[0044] Adopt the method of the present invention to treat wastewater, first add polyacrylamide, the dosage is 10mg / L, then add polyferric sulfate, the dosage is 80mg / L, filter to remove the precipitate, and use a batch centrifuge to filter , the rotating speed is controlled at 3000rpm, and the centrifugation time is 5min. The concentration of suspended solids in the coagulation effluent drops below 500mg / L, and the pH value is 7.8. The coagulation effluent enters the fully mixed anaerobic reactor, and at the same time, the concentrated bacterial solution of Pseudomonas stutzeri FSTB-5 obtained from the above culture is added at 0.5% of the volume of the treated wastewater per hour. The operating conditions of the anaerobic biochemical treatment are: the hydraulic retention time is 24 hours,...

technical field

[0001] The invention belongs to the technical field of waste water treatment, and in particular relates to a treatment method for waste water produced by vancomycin. Background technique

[0002] Antibiotics are a great discovery in human history. They have been widely used in medical and other fields, effectively protecting human health. However, during the production and application of antibiotics, a large amount of refractory organic wastewater containing antibiotics will be produced. Vancomycin is a glycopeptide antibiotic that interferes with cell wall synthesis by interfering with a key component in cell wall structure, inhibiting the production of phospholipids and peptides in the cell wall. Vancomycin production wastewater mainly comes from the main processes of macroporous adsorption resin elution, decolorization, gelation, etc., and is concentrated by reverse osmosis.

[0003] The wastewater contains bacteria that produce vancomycin, acetone, etha...

Examples

Embodiment 1

[0037] The quality of wastewater produced by a vancomycin production process in a factory is: COD (Cr method, the same below) is 110,000 mg / L, pH is 4.0, and ammonia nitrogen is 500 mg / L.

[0038] Adopt the method of the present invention to treat wastewater, first add polyacrylamide, the dosage is 10mg / L, then add polyferric sulfate, the dosage is 60mg / L, filter to remove sediment, and use intermittent centrifuge to filter , the rotating speed is controlled at 3000rpm, and the centrifugation time is 5min. The concentration of suspended solids in the coagulation effluent drops below 500mg / L, and the pH value is 7.8. The coagulation effluent enters the internal circulation anaerobic reactor (IC), and at the same time, the concentrated bacterial solution of Pseudomonas stutzeri FSTB-5 obtained from the above culture is added at 0.3% of the volume of the treated wastewater per hour. The operating conditions of the anaerobic biochemical treatment are: the hydraulic retention time...

Embodiment 2

[0040] The quality of wastewater produced by a vancomycin production process in a factory is: COD (Cr method, the same below) is 120,000 mg / L, pH is 3.5, and ammonia nitrogen is 600 g / L.

[0041] Adopt the method of the present invention to treat the waste water, first add polyacrylamide, the dosage is 5mg / L, then add ferric chloride, the dosage is 100mg / L, filter and remove the precipitate, and use a batch centrifuge to carry out For filtration, the rotating speed is controlled at 3000rpm, and the centrifugation time is 5min. The concentration of suspended solids in the coagulation effluent drops below 500mg / L, and the pH value is 7.5. The coagulation effluent enters the fully mixed anaerobic reactor, and at the same time, the concentrated bacterial solution of Pseudomonas stutzeri FSTB-5 obtained from the above culture is added at 0.5% of the volume of the treated wastewater per hour. The operating conditions of the anaerobic biochemical treatment are: the hydraulic retenti...

Embodiment 3

[0043] The quality of wastewater produced by a vancomycin production process in a factory is: COD (Cr method, the same below) is 120,000 mg / L, pH is 3.5, and ammonia nitrogen is 600 g / L.

[0044] Adopt the method of the present invention to treat wastewater, first add polyacrylamide, the dosage is 10mg / L, then add polyferric sulfate, the dosage is 80mg / L, filter to remove the precipitate, and use a batch centrifuge to filter , the rotating speed is controlled at 3000rpm, and the centrifugation time is 5min. The concentration of suspended solids in the coagulation effluent drops below 500mg / L, and the pH value is 7.8. The coagulation effluent enters the fully mixed anaerobic reactor, and at the same time, the concentrated bacterial solution of Pseudomonas stutzeri FSTB-5 obtained from the above culture is added at 0.5% of the volume of the treated wastewater per hour. The operating conditions of the anaerobic biochemical treatment are: the hydraulic retention time is 24 hours,...

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