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Salicylic acid solid microcapsule and preparation method thereof

A technology of salicylic acid and microcapsules, which is applied in the field of salicylic acid solid microcapsules and its preparation, can solve the problems of strong irritation, insoluble in water, application restrictions, etc., to reduce irritation, enhance antibacterial effect, The effect of water solubility enhancement

Inactive Publication Date: 2017-07-04
佛山市禅香新材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Salicylic acid is currently the mainstream of anti-acne products in the field of cosmetics, but it is insoluble in water and has strong irritation, so its application is greatly limited
The prior art has relevant reports disclosing chitosan salicylic acid microcapsules. Although this can reduce the irritation to the skin, its water solubility is still not good enough, and it affects the release of salicylic acid itself.

Method used

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  • Salicylic acid solid microcapsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] The preparation of embodiment 1 salicylic acid solid microcapsule

[0010] Get 30g of salicylic acid and 120g of sodium carboxymethylcellulose. Mixing, stirring and homogenizing salicylic acid and sodium carboxymethyl cellulose, and spray drying to obtain salicylic acid solid microcapsules.

Embodiment 2

[0011] The preparation of embodiment 2 salicylic acid solid microcapsules

[0012] Get 30g of salicylic acid and 150g of sodium carboxymethylcellulose. Mixing, stirring and homogenizing salicylic acid and sodium carboxymethyl cellulose, and spray drying to obtain salicylic acid solid microcapsules.

Embodiment 3

[0013] The preparation of embodiment 3 salicylic acid solid microcapsules

[0014] Get 30g of salicylic acid and 180g of sodium carboxymethylcellulose. Mixing, stirring and homogenizing salicylic acid and sodium carboxymethyl cellulose, and spray drying to obtain salicylic acid solid microcapsules.

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Abstract

The invention discloses a salicylic acid solid microcapsule and a preparation method thereof. The salicylic acid solid microcapsule is composed of a wall material and a core material with the mass ratio of (4-6):1. The core material is salicylic acid, and the wall material is sodium carboxymethyl cellulose. The prepared salicylic acid microcapsule can reduce the original irritation of salicylic acid and greatly enhances the water solubility, so that salicylic acid can be more fully applied to cosmetics, and the bacteriostatic effect is greatly enhanced.

Description

technical field [0001] The invention belongs to the technical field of microcapsules, in particular to a salicylic acid solid microcapsule and a preparation method thereof. Background technique [0002] Salicylic acid is a β-hydroxy acid (Beta Hydroxy Acid), also known as BHA, B skin softening fruit acid, which exists in willow bark, white pearl leaves and sweet birch in nature. Salicylic acid is a fat-soluble organic acid. Salicylic acid can dissolve excess oil in facial pores and dead and damaged keratinocytes, inhibit sebum secretion and bacterial growth, and can also lighten pigmented spots, shrink pores, remove fine wrinkles and improve aging caused by sun exposure. Salicylic acid is currently the mainstream of anti-acne products in the field of cosmetics, but it is insoluble in water and has strong irritation, so its application is greatly limited. In the prior art, there are relevant reports disclosing chitosan salicylic acid microcapsules. Although this can reduce ...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/368A61K8/11A61Q17/00A61Q19/08
CPCA61K8/731A61K8/11A61K8/368A61K2800/56A61Q17/005A61Q19/08
Inventor 林名钦
Owner 佛山市禅香新材料有限公司