Degradable blood vessel anastomat provided with drug membrane layer and preparation process of degradable blood vessel anastomat

Abstract

The invention discloses a degradable blood vessel stapler with a drug film layer and a preparation process thereof, comprising a sleeve made of degradable metal materials; Pore ​​structure; the inner wall and / or outer wall of the casing is provided with a drug film layer, and the drug film layer is a polymer film containing a drug component or a biofilm containing a drug component. The vascular stapler of the present invention can quickly and effectively connect end-to-end vascular intima without suturing, is convenient for anastomosis, is well positioned, and is not easy to move; moreover, the surface of the thin tube wall of the vascular stapler is not only beneficial to the intima tissue of the host vessel Crawling, growing, covering, fast healing, and effective treatment of vascular diseases; at the same time, the sleeve can play a supporting role and improve the patency of blood vessels, especially after the vascular intima heals, the degradable sleeve can quickly degrade and remove from the body The clinical events such as restenosis and complications in the late stage of non-degradable drug-eluting stents were solved.

Description

technical field [0001] The invention relates to a medical device, in particular to a degradable blood vessel stapler with a drug film layer and a preparation process thereof, which is suitable for end-to-end connection of lumen parts, especially blood vessel anastomosis. Background technique [0002] In minimally invasive interventional surgery, the end-to-end anastomosis of blood vessels, especially the anastomosis and connection of the two ends of the severed blood vessels, is one of the most basic techniques. The quality of anastomosis techniques and methods directly affects the success or failure of tissue and organ transplantation. At present, the traditional method is the most effective suturing method, but the process is complicated, the steps are cumbersome, the operation is difficult, the technique requires high precision, and the anastomosis requires less trauma. The suturing process is accurate and fast, but it is time-consuming and laborious in clinical operations...

AI Technical Summary

Problems solved by technology

But also there are following problems: 1, it comprises two identical end pipes and a sleeve pipe, has the shortcoming of complex structure and troublesome operation

2. Since the vascular stapler cannot be positioned well, it is prone to movement

3. The surface of the vascular stapler is not conducive to the crawling, growth, and coverage of the host vascular intima tissue, which slows down the healing speed

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