Unlock instant, AI-driven research and patent intelligence for your innovation.

Extraction method of seabuckthorn flavone

A technology of seabuckthorn flavonoids and extraction methods, which is applied in the direction of medical formulas, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of low yield of seabuckthorn flavonoids, and achieve the goals of reducing losses, increasing yields, and improving utilization rates Effect

Inactive Publication Date: 2017-08-04
张掖市润星生物科技有限公司
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to provide a method for extracting seabuckthorn flavonoids, which solves the problem of low yield of seabuckthorn flavonoids extracted by existing methods

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A method for extracting seabuckthorn flavonoids, comprising:

[0027] Selection of raw materials: select the pulp and leaves of seabuckthorn, wash them and crush them as raw materials;

[0028] Extraction: adopt the echinoflavone in the raw material of supercritical carbon dioxide extraction, entrainer is ethanol, ethanol and raw material mass ratio are 4:1, and raw material accounts for 6.5% of extraction solvent total volume; The flow rate of solvent carbon dioxide during described supercritical carbon dioxide extraction is 15L / h, the pressure is 33MPa, the extraction temperature is 45°C, and the extraction time is 1.5h. After the extraction is completed, the mixture A is obtained and the mixture A is subjected to solid-liquid separation to obtain the extract B and the solid C;

[0029] Concentration: Evaporate the extract B under reduced pressure, the evaporation under reduced pressure is rotary evaporation concentration, the pressure of rotary evaporation concentra...

Embodiment 2

[0034] A method for extracting seabuckthorn flavonoids, comprising:

[0035] Selection of raw materials: select the pulp and leaves of seabuckthorn, wash them and crush them as raw materials;

[0036] Extraction: adopt the echinoflavone in the raw material of supercritical carbon dioxide extraction, entrainer is ethanol, ethanol and raw material mass ratio are 8:1, and raw material accounts for 8.5% of extraction solvent total volume; The flow rate of solvent carbon dioxide during described supercritical carbon dioxide extraction is 20L / h, the pressure is 35MPa, the extraction temperature is 50°C, and the extraction time is 2.5h. After the extraction is completed, the mixture A is obtained and the mixture A is subjected to solid-liquid separation to obtain the extract B and the solid C;

[0037] Concentration: Evaporate the extract B under reduced pressure, the evaporation under reduced pressure is rotary evaporation concentration, the pressure of rotary evaporation concentra...

Embodiment 3

[0042] A method for extracting seabuckthorn flavonoids, comprising:

[0043] Selection of raw materials: select the pulp and leaves of seabuckthorn, wash them and crush them as raw materials;

[0044] Extraction: adopt the echinoflavone in the raw material of supercritical carbon dioxide extraction, entrainer is ethanol, ethanol and raw material mass ratio are 6:1, and raw material accounts for 7% of extraction solvent total volume; The flow rate of solvent carbon dioxide during described supercritical carbon dioxide extraction is 17L / h, the pressure is 34MPa, the extraction temperature is 48°C, and the extraction time is 2h. After the extraction is completed, the mixture A is obtained and the mixture A is subjected to solid-liquid separation to obtain the extract B and the solid C;

[0045] Concentration: Evaporate the extract B under reduced pressure, the evaporation under reduced pressure is concentrated by rotary evaporation, the pressure of rotary evaporation is 0.015MPa...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an extraction method of seabuckthorn flavone. The extraction method comprises the following steps: selecting a raw material: selecting pulp and leaves of seabuckthorn, cleaning the pulp and leaves thoroughly and crushing the same to be used as the raw material; extraction: adding a solvent into the raw material to extract to obtain a mixture A and performing solid and liquid separation on the mixture A to obtain an extraction liquid B and a solid C; concentration: evaporating the extraction liquid B at a reduced pressure to obtain a concentrate D and recovering the solvent; degreasing: degreasing and filtering the concentrate D to obtain a paste E and a solid F; and drying: drying the paste E to obtain a seabuckthorn flavone finished product. By primary extraction, the yield of seabuckthorn flavone can reach 98.5% and the mass percentage of seabuckthorn flavone can reach 40%. The obtained seabuckthorn flavone product meets the requirement of state health standards. The used solvent and entrainer in the application can be recovered and recycled, and the waste of the reagent is only about 3%.

Description

technical field [0001] The invention relates to the processing field of seabuckthorn, in particular to a method for extracting seabuckthorn flavonoids. Background technique [0002] Seabuckthorn flavonoids contain active ingredients such as quercetin, isorhamnetin and kaempferol, which have the functions of lowering blood pressure, lowering blood fat, reducing blood viscosity, enhancing blood vessel elasticity, and anti-atherosclerosis. It is the "killer of cardiovascular and cerebrovascular diseases" ". As the incidence of cardiovascular and cerebrovascular diseases in middle-aged and elderly people continues to increase, people's awareness of their prevention is also gradually increasing, and the demand for seabuckthorn flavonoids, the "nemesis" of cardiovascular and cerebrovascular diseases, is also increasing. An efficient extraction method of seabuckthorn flavonoids is particularly important. Contents of the invention [0003] The object of the present invention is ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P9/12A61P3/06A61P7/00A61P9/10A61K127/00A61K131/00
Inventor 闫广洽
Owner 张掖市润星生物科技有限公司