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System and method for extracting global LFP (Late Follicular Phase) Parkinsonism feature value

A technology for Parkinson's disease and feature extraction, applied in the fields of application, electrotherapy, medical science, etc., can solve the problems that patients cannot provide pulse stimulation frequency and intensity, and achieve the effect of increasing diversity, reducing operation steps, and reducing module settings

Active Publication Date: 2017-08-11
CHONGQING UNIV OF POSTS & TELECOMM
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AI Technical Summary

Problems solved by technology

[0010] The present invention intends to provide a system for extracting global LFP Parkinson's disease eigenvalues, to solve the existing pacemaker because there is no objective Parkinson's disease eigenvalue that does not depend on the doctor's experience. When relying too much on human experience, it is impossible to provide patients with accurate, appropriate and predictable frequency and intensity of pulse stimulation

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  • System and method for extracting global LFP (Late Follicular Phase) Parkinsonism feature value
  • System and method for extracting global LFP (Late Follicular Phase) Parkinsonism feature value
  • System and method for extracting global LFP (Late Follicular Phase) Parkinsonism feature value

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Embodiment

[0055] Such as figure 1 As shown, the system for global LFP Parkinson's feature value extraction includes:

[0056] The signal transceiver module 1 collects the field potential signal of the STN or GPi site through the implanted electrodes; simultaneously generates stimulation pulses and measures the LFP signal; the signal transceiver module 1 is a microelectrode comprising at least two sets of contacts, and the two sets of contacts A filter circuit is connected between them.

[0057] Feature extraction module 2 is used for feature extraction of the field potential signal; connected with signal transceiver module 1, it is used to perform energy analysis on the LFP signal measured by signal transceiver module 1, and perform spectrum segmentation of the LFP signal according to the analysis results to extract each Eigenvalues ​​of frequency bands;

[0058] The comprehensive processing module 3 is connected with the feature extraction module 2, and the eigenvalue of each frequen...

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Abstract

The invention discloses a system and a method for extracting a global LFP (Late Follicular Phase) Parkinsonism feature value. The system comprises a signal transceiving module, a feature extraction module, a comprehensive processing module and an output module, wherein the signal transceiving module is used for generating stimulation pulses and measuring LFP signals at the same time; the feature extraction module is used for performing energy analysis on the LFP signals measured by the signal transceiving module, and extracting the feature value of each band; the comprehensive processing module is used for calculating correlation coefficients of bands and energy baseline spectra according to the difference between the feature value of each band and each corresponding point on the energy baseline spectra; and the output module is used for adding the products of the feature values and correlation coefficients of the bands to obtain a global LFP Parkinsonism feature value. The LFP signals are preprocessed into a low frequency band, an intermediate frequency band and a high frequency band; the preprocessed signals are converted from a time domain to a frequency domain for analyzing, an autoregressive model and a neural network model are established using the feature value of each band as a parameter and using the correlation coefficient of each band as a weight, and a global feature value which is objective and accurate and does not depend on doctor experience is obtained.

Description

technical field [0001] The invention relates to the field of electroencephalogram digital data processing, in particular to a system and method for global LEP Parkinson's feature value extraction for brain pacemakers. Background technique [0002] Parkinson's disease (PD) is a common neurodegenerative disease, and pacemaker surgery is one of the main methods for the treatment of Parkinson's disease. A brain pacemaker is a small, delicate microelectronic device that includes a pulse generator, a set of electrodes, and extended wires connected between the pulse generator and the electrodes. [0003] Brain pacemaker surgery is a common name for deep brain stimulation (DBS). Electrodes implanted in the brain are used to send out weak electrical pulses to stimulate the relevant nerve nuclei that control movement in the brain and inhibit abnormal brain nerves that cause symptoms of Parkinson's disease. Signal, thereby eliminating the symptoms of Parkinson's disease, so that patie...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N1/36A61N1/372A61B5/0476
CPCA61B5/6868A61B5/7225A61B5/7235A61N1/36067A61N1/36139A61B5/369
Inventor 孙齐峰赵德春王力李文瀚方程赵兴田银
Owner CHONGQING UNIV OF POSTS & TELECOMM
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