Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Applications of thyroid hormone, and pharmaceutically acceptable salts or prodrugs of thyroid hormone in preparing drugs used for treating and/or preventing pulmonary diseases

A thyroid hormone, lung disease technology, applied in the field of thyroid hormone and its pharmaceutically acceptable salt or prodrug

Inactive Publication Date: 2017-08-15
深圳市润佳通科技有限公司
View PDF1 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, so far there has been no report on the use of thyroid hormones and their pharmaceutically acceptable salts or prodrugs for the treatment and / or prevention of lung diseases

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Applications of thyroid hormone, and pharmaceutically acceptable salts or prodrugs of thyroid hormone in preparing drugs used for treating and/or preventing pulmonary diseases
  • Applications of thyroid hormone, and pharmaceutically acceptable salts or prodrugs of thyroid hormone in preparing drugs used for treating and/or preventing pulmonary diseases
  • Applications of thyroid hormone, and pharmaceutically acceptable salts or prodrugs of thyroid hormone in preparing drugs used for treating and/or preventing pulmonary diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0099] Preparation of thyroxine nebulizer:

[0100] Take thyroxine or its sodium salt, dissolve it in an alkaline solution such as sodium hydroxide, the concentration can reach 5mg / ml, and then dilute it 250 times with normal saline (with a small amount of modified ingredients) as a storage solution. When in use, take 1-5ml of storage solution, dilute to a certain volume, select the corresponding nebulizer for nebulization, the nebulization time is 15-20 minutes, (if you use an Omron nebulizer, nebulize 10ml, about for 15 minutes).

[0101] The specific implementation of the present invention will be described below in conjunction with the accompanying drawings.

[0102] Figure 1-5 It shows that DIO2 is greatly up-regulated in the lung tissue of patients with idiopathic pulmonary fibrosis. in, figure 1 Gene expression analysis using the microarray platform demonstrated that DIO2 was one of the most significantly up-regulated genes (p=5.4E-7), idiopathic pulmonary fibrosis p...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
diameteraaaaaaaaaa
Login to View More

Abstract

The invention provides novel applications of thyroid hormone, and pharmaceutically acceptable salts or prodrugs of thyroid hormone. According to the invention, thyroid hormone, and the pharmaceutically acceptable salts or prodrugs of thyroid hormone can be used for treating and / or preventing pulmonary diseases; thyroid hormone and the pharmaceutically acceptable salts or prodrugs of thyroid hormone can be used for protecting alveolar epithelial cells effectively, adjusting surface protein synthesis, storage, and distribution of alveolar epithelial cells, promoting maturation, differentiation, and cell integrity of alveolar epithelial cells, promoting repairing of damaged mitochondria in alveolar epithelial cells, improving mitochondria biosynthesis, preventing and reversing pulmonary fibrosis, adjusting immunity reaction, changing cancerous environment, treating and preventing pulmonary diseases, improving pulmonary functions such as gas exchange, and achieving treatment effect, and are beneficial for cleaning of pulmonary effusion and repairing of damaged lung tissue.

Description

technical field [0001] The present invention relates to a new application of thyroid hormone and its pharmaceutically acceptable salt or prodrug, in particular to a kind of thyroid hormone and its pharmaceutically acceptable salt or prodrug in the preparation of treatment and / or prevention of lung diseases application in medicine. Background technique [0002] Microbial populations in the air in the living environment, indoor and outdoor air pollution, including smoking, can directly cause lung tissue damage in people susceptible to lung diseases, cause lesions, and can cause inflammation, acute lung injury, pulmonary fibrosis, lung cancer, etc. disease. What is even more concerning is that with the rapid development of my country's economy, environmental pollution is becoming more and more serious, especially the current severe smog situation. Such a bad air environment is bound to threaten the lungs of the general public, and the number of respiratory patients will incre...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/198A61P11/00A61P35/00
CPCA61K31/198
Inventor 余国营
Owner 深圳市润佳通科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com