Bi-component compound artemether dry suspension for treating malaria and preparation method of dry suspension

Abstract

The invention discloses a bi-component compound artemether dry suspension for treating malaria and a preparation method of the dry suspension. The dry suspension is characterized by being prepared from the following raw materials in parts by weight: original auxiliary materials: 0.05-0.10 part of artemether, 0.2-0.8 part of lumefantrine, 2.5-4 parts of saccharose, 2-3 parts of lactose, 0.05-0.3 part of aspartame, 0.05-0.15 part of sodium carboxymethylcellulose and 1-2 parts of 60% ethanol; and additional auxiliary materials: 0.03-0.10 part of xanthan gum, 0.03-0.10 part of a coconut essence, 0.03-0.10 part of a fresh milk flavor and 0.15-0.35 part of silicon dioxide. The bi-component compound artemether dry suspension is sweet and fragrant after being eaten, is easily accepted by children and is obvious in action effect.

Description

technical field [0001] The invention relates to the technical field of malaria treatment, in particular to a two-component compound artemether dry suspension for treating malaria and a preparation method thereof. Background technique [0002] Malaria is a vector-borne disease caused by infection with Plasmodium parasites through mosquito bites or blood transfusion of people with Plasmodium parasites. The main manifestations of this disease are periodic attacks, chills, fever, and sweating all over the body. After repeated attacks for a long time, anemia and splenomegaly can be caused. At present, antimalarial drugs can be prepared from artemisinin, artemether, artesunate and the like. However, most of them are prepared by unilateral preparations such as artemisinin or its derivatives. Although artemisinin derivatives have a good effect on the treatment of malaria, the therapeutic effect sometimes depends on the unilateral preparation, dosage, and administration. The shape ...

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Problems solved by technology

However, most of them are prepared by unilateral preparations such as artemisinin or its derivatives. Although artemisinin derivatives have a good effect on the treatment of malaria, the therapeutic effect sometimes depends on the unilateral preparation, dosage, and administration. The shape and the stability of the transportation process are affected, especially in areas such as Africa with high temperature, drought and unsatisfactory sanitation conditions, there is a need for a drug for treating malaria that is suitable for children and has a good taste

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