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Frequency-domain regularization phase extraction method for non-ideal phase-contrast imaging system

A phase contrast imaging, non-ideal technology, applied in the field of biomedical engineering and medical imaging, can solve the problem of inaccurate acquisition of phase information

Inactive Publication Date: 2017-09-29
TIANJIN UNIV
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Problems solved by technology

The traditional phase extraction method obtains the analytical solution of the phase by approximating the spatial domain model of phase contrast imaging. This method can obtain effective phase information in the case of high-quality imaging, but for the imaging system with defects, This phase extraction method based on the ideal model in the space domain often cannot accurately obtain the phase information

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  • Frequency-domain regularization phase extraction method for non-ideal phase-contrast imaging system
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  • Frequency-domain regularization phase extraction method for non-ideal phase-contrast imaging system

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Embodiment Construction

[0022] The present invention will be described below in conjunction with embodiment and accompanying drawing

[0023] 1. Digital X-ray imaging system

[0024] The experiment adopts self-constructed micro-focus source digital radiography system. The detector of the system is a 1024×1024 CCD array with a pixel size of 50 μm×50 μm and 14 gray levels. The horizontal and vertical spatial resolutions are 20 pixels per millimeter. The focal spot size of the X-ray tube is 50 μm. In the experiment, the working voltage of the X-ray source is 80kVp, and the working current is 0.5mA. The imaging objects were constructed using polyethylene fibers with diameters of 100 μm, 50 μm, 20 μm and 10 μm. The experiment sets the distance from the X-ray source to the object as 100cm, and the corresponding distance from the object to the detector as 100cm. Under the above settings, the focal spot image formed by the light source on the detector is 50 μm. Since the point spread function of the im...

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Abstract

The invention relates to a frequency-domain regularization phase extraction method for a non-ideal phase-contrast imaging system. The method comprises: a cutter edge image is collected and a corresponding line diffusion function representing system characteristics is obtained; a value of MTF(u-) is obtained; an imaging object is placed and imaging is carried out to obtain an imaging result; Fourier transform is carried out on the imaging result; an imaging model in a matrix manner is constructed; iterative calculation is carried out to obtain a temporary solution of an all-frequency-range absorption item; on the basis of a rapid gradient projection algorithm, an absorption item including phase information is obtained; and a phase information image representing the internal structure of the object is obtained.

Description

technical field [0001] The invention belongs to the fields of biomedical engineering and medical imaging, and relates to a frequency domain regularized phase extraction method for non-ideal phase contrast imaging systems. Background technique [0002] Breast cancer is currently the number one "killer" of women. According to the latest statistics in 2015, the number of breast cancer patients and deaths worldwide increased to 1.7 million and 520,000 in 2012, accounting for 25% and 520,000 of all female cancer cases respectively. 15% of cancer deaths [2]. my country has a large population, and the prevalence of breast cancer has shown a clear upward trend in recent years. The diagnosis and treatment of breast cancer has become an increasingly serious social problem that needs to be solved urgently. Early diagnosis is the key to solving this social problem and improving the survival rate and life of patients. The key to quality. [0003] The current main method of routine breas...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T7/00
CPCG06T7/0012G06T2207/10116G06T2207/20056G06T2207/30068
Inventor 周仲兴郭柏宽孙啸然高峰赵会娟
Owner TIANJIN UNIV
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