Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicinal composition for treating rheumatoid arthritis

A composition and arthritis technology, applied in the direction of drug combination, antipyretics, anti-inflammatory agents, etc., can solve the problems of late curative effect, large toxic and side effects of liver, kidney and blood system, and failure to prevent the progression of the disease, so as to relieve related symptoms Effect

Active Publication Date: 2017-10-10
石岳明
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Non-steroidal drugs are currently the most widely used class of drugs. Although they can relieve symptoms relatively quickly, they cannot prevent the progression of the disease, and have relatively large toxic and side effects such as gastrointestinal reactions and blood system damage; slow-acting antirheumatic drugs Although it has a certain control effect on the progress of the disease, the curative effect appears late, and long-term use has serious side effects on the liver, kidney and blood system; glucocorticoids have a strong anti-inflammatory effect and can quickly relieve rheumatoid arthritis. However, due to a certain one-sided understanding of the application of hormones, misuse and abuse are still quite common in current clinical work, often causing serious adverse consequences to patients

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicinal composition for treating rheumatoid arthritis
  • Traditional Chinese medicinal composition for treating rheumatoid arthritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0114] Prescription: Tripterygium wilfordii 104.7g, Rehmannia glutinosa 16.8g, Cangzhu 33.6g, Lonicera vine 33.6g, Tribulus terrestris 33.6g, Codonopsis 56g, wolfberry 20g;

[0115] Preparation method: Decoct the above seven flavors with water twice, the first time for 2 hours, the second time for 1.5 hours, filter, combine the filtrate, let stand, filter, the filtrate is concentrated under reduced pressure to a relative density of 1.02-1.06 (60°C), add Sodium benzoate 3g, stir well, let it stand for 24 hours, filter, add water to adjust the total amount to 1000ml, filter, subpackage, sterilize, and obtain.

[0116] Functions and indications: nourishing qi and nourishing yin, detoxifying and dredging collaterals. It is used for red, swollen and hot pain in the extremities of the whole body caused by deficiency of both qi and yin, heat and toxin blockage of collaterals, accompanied by fever, thirst, dysphoria, shortness of breath, sweating, etc. It is suitable for rheumatoid ar...

Embodiment 2

[0120] Prescription: Tripterygium 98g, Rehmannia 20g, Atractylodes 45g, Lonicera vine 25g, Tribulus terrestris 45g, Codonopsis 60g, wolfberry 14g;

[0121] Preparation method: Take the raw material medicine of the prescribed amount, add 12 times the amount of 70% ethanol to reflux and extract twice, each time for 1.5 hours; combine the extracts, filter, recover ethanol and concentrate; the concentrate is dried under reduced pressure, crushed into fine powder, Add conventional excipients, mix well; dry-compress granules, tablet, that is.

Embodiment 3

[0123] Prescription: Tripterygium wilfordii 110g, Rehmannia glutinosa 12g, Cangzhu 45g, Lonicera vine 25g, Tribulus terrestris 45g, Codonopsis 50g, Lycium barbarum 22g;

[0124] Preparation method: take the raw material drug in the prescribed amount, add water and decoct twice, the first time is 2 hours, the second time is 1.5 hours, combine the decoction, filter, concentrate the filtrate, add ethanol to the concentrated solution until the alcohol content is 80%, Stand still, filter, recover the ethanol from the filtrate until it has no alcohol smell, concentrate and dry, pulverize into fine powder, add auxiliary materials, mix well; dry press granules, and obtain.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a traditional Chinese medicinal composition for treating rheumatoid arthritis. The traditional Chinese medicinal composition is prepared from the following crude drugs in parts by weight: 50-210 parts of tripterygium wilfordii, 5-50 parts of radix rehmanniae recen, 10-90 parts of rhizoma atractylodis, 10-90 parts of caulis lonicerae, 10-90 parts of tribulus terrestris, 25-120 parts of radix codonopsis and 10-30 parts of fruit of Chinese wolfberry, wherein the ratio of tripterygium wilfordii to fruit of Chinese wolfberry is 5-7 to 1. Clinical research proves that the total effective rate of the traditional Chinese medicinal composition on rheumatoid arthritis can reach 95.6%, can effectively relieve related symptoms, and is safe and effective.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating rheumatoid arthritis, and belongs to the field of traditional Chinese medicine. Background technique [0002] Rheumatoid arthritis is a chronic systemic autoimmune disease mainly characterized by joint lesions. It often has joint erosions and progressive joint deformities. It has a high disability rate and seriously affects the work, living ability and quality of life of patients. The anti-rheumatic western medicines used for the treatment of rheumatoid arthritis mainly include non-steroidal anti-inflammatory drugs, slow-acting anti-rheumatic drugs, and adrenocortical hormones. Non-steroidal drugs are currently the most widely used class of drugs. Although they can relieve symptoms relatively quickly, they cannot prevent the progression of the disease, and have relatively large toxic and side effects such as gast...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/815A61P29/00A61P19/02
CPCA61K36/185A61K36/284A61K36/344A61K36/355A61K36/37A61K36/804A61K36/815A61K2300/00
Inventor 侯丽萍石秀峰
Owner 石岳明
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com