Composition, application, compound preparation and preparation method for removing chloasma

A compound preparation and technology for chloasma, applied in preparations for toiletry, preparations for skin care, medical preparations containing active ingredients, etc.

Active Publication Date: 2020-08-11
YUNNAN BOTANEE BIO TECH GRP CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] Existing technology 2: The patent application number is 201510559435.4, and the name is a compound whitening composition containing tea leaf extract from Dianshan Mountain, its preparation and its preparation method. Acanthopanax extract, etc. are used as active ingredients to whiten, remove freckles, and beautify the skin, but they only highlight whitening, but do not fundamentally relieve and long-term treat chloasma

Method used

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  • Composition, application, compound preparation and preparation method for removing chloasma
  • Composition, application, compound preparation and preparation method for removing chloasma
  • Composition, application, compound preparation and preparation method for removing chloasma

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preparation example Construction

[0044] The preparation method of the compound preparation for removing chloasma comprises the following steps:

[0045] The first premix preparation step: use polydimethylsiloxane to wet and disperse the acrylic (ester) / C10-30 alkanol acrylate crosslinked polymer to a homogeneous phase to obtain the first premix;

[0046] The second premix preparation step: wetting and dispersing the xanthan gum with glycerol to a homogeneous phase to obtain the second premix;

[0047] Water phase material preparation steps: at room temperature, make carbomer swell in deionized water, and after stirring to dissolve carbomer in deionized water, put the first premix in deionized water and continue stirring until homogeneous , and then add the second premixed material at 80-85°C, and continue stirring until homogeneous, to obtain the water phase material;

[0048] The oil phase material is prepared through the following steps:

[0049] The third premix preparation step: using a mixture of isost...

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Abstract

The invention discloses a chloasma removing composition. The composition uses nicotinamide for inhibiting melanin formation, tranexamic acid for inhibiting melanin aggregation, inhibiting vasodilatation and eliminating inflammations, Camellia reticulate extract for inhibiting melanin formation, inhibiting histamine release and relieving irritation, and total Panax notoginseng saponins for improving blood vessel microcirculation and improving the skin tolerance, and the above four components are reasonably proportioned to well realize the alleviation or long-term treatment of mixed chloasma. The invention also provides a chloasma removing composite preparation. The composite preparation can realize the effective co-dissolving and combined action of the nicotinamide, tranexamic acid, total Panax notoginseng saponins and Camellia reticulate extract in the composite preparation in order to realize the alleviation or long-term treatment of mixed chloasma, and the composite preparation also has the advantages of no irritation, ensuring of use by allergic patients, and no phase slitting when preserved at room temperature. The invention further provides a preparation method of the chloasma removing composite preparation and an application of the chloasma removing composition.

Description

technical field [0001] The invention discloses a composition for removing chloasma and its application, a compound preparation and a preparation method of the compound preparation, which are suitable for the fields of medicine and cosmetics. Background technique [0002] Melasma is a common facial pigmentation disease. It is a kind of pigmentation with high incidence of colored skin, especially Asians. The cause of the disease has not been fully elucidated. The pathogenesis mainly includes pigmentation and increased vascular reactivity. , vascular microcirculation disturbance, inflammatory response and impaired skin barrier function. For the classification of melasma, He Li et al proposed the classification of vascular type (V), pigmented type (M), and mixed type. The mixed type of chloasma includes pigment-dominant type (M>V) and vascular-dominant type ( V>M). [0003] According to the classification of chloasma, for pigmented chloasma, currently commonly used exter...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/67A61K8/44A61Q19/02
CPCA61K8/44A61K8/675A61K8/97A61K2800/782A61Q19/02
Inventor 何黎宋春晓马骁王飞飞刘海洋郭振宇
Owner YUNNAN BOTANEE BIO TECH GRP CO LTD
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