Dual-mode imaging system and method for achieving XCT and photoacoustic tomography

A dual-mode imaging and photoacoustic imaging technology, which is applied in the direction of acoustic wave diagnosis, infrasonic wave diagnosis, and diagnosis using light, can solve problems such as difficulty in interpretation and lack of structural information in photoacoustic imaging, and achieve the effect of enhancing accuracy

Active Publication Date: 2017-12-19
PEKING UNIV
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Problems solved by technology

[0004] In order to solve the problem of difficult interpretation due to lack of sufficient structural information in photoacoustic imaging, the present invention proposes a dual-mode imaging system of X-ray computed tomography (XCT) and photoacoustic imaging and its imaging method. Combined with XCT on the same machine, it becomes a new dual-mode imaging system with complementary information

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  • Dual-mode imaging system and method for achieving XCT and photoacoustic tomography
  • Dual-mode imaging system and method for achieving XCT and photoacoustic tomography

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Embodiment Construction

[0036] The present invention will be further elaborated below through specific embodiments in conjunction with the accompanying drawings.

[0037] Such as figure 1 As shown, the dual-mode imaging system for realizing XCT and photoacoustic imaging in this embodiment includes: a pulsed laser 1, a beam expander 2, an optical fiber bundle 3, a water tank 6, a rotary table 7, a waterproof bearing 4, an X-ray source 10, and a radiation protection Board 8, X-ray detector 11, ultrasonic array 9, ultrasonic acquisition system and computer; Wherein, as figure 2 As shown, a waterproof bearing 4 is arranged at the bottom of the water tank 6, and the rotary table 7 is arranged on the bottom of the water tank through the waterproof bearing. The waterproof bearing makes the sealing between the rotary table and the bottom of the water tank, and the rotary table 7 is connected to an external motor; the sample is placed On a rotating table, submerged in water; the X-ray source is located on o...

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Abstract

The invention discloses a dual-mode imaging system and method for achieving XCT and photoacoustic tomography. The mode of photoacoustic and XCT dual-mode same-machine fused imaging is adopted, photoacoustic tomography tissue optical absorption comparison and XCT density comparison are combined, the interpretation accuracy of a photoacoustic tomography structure is further improved, and information complementary dual-mode imaging is achieved. A traditional vertical hanging rotation mode is changed, a rotary table is arranged at the bottom of a water trough, sealing between the rotary table and the bottom of the water trough is achieved through a waterproof bearing, the water trough is fixed, a sample is immersed in water, the rotary table rotates to drive the sample to rotate, accordingly 360-degree sample scanning is completed, and it is ensured that the water trough is water-tight and a photoacoustic signal of the sample is conducted in an undamped mode.

Description

technical field [0001] The invention relates to animal or other sample imaging technology, in particular to a dual-mode imaging system and an imaging method for realizing XCT and photoacoustic imaging. Background technique [0002] Photoacoustic imaging (PAT) is a tomographic imaging technique based on the photoacoustic effect. This imaging technology combines the high contrast of optical imaging and the high-resolution characteristics of ultrasound imaging, and can obtain high-resolution images in deeper tissues. It has shown great potential in the functional and molecular imaging of deep animal tissues. [0003] However, the interpretation of soft tissue imaging or molecular imaging by photoacoustic imaging becomes relatively difficult due to the lack of sufficient structural information. This is mainly because many tissues and organs have unclear boundaries in photoacoustic imaging, making it difficult to determine the anatomical location of the image results. Especiall...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B6/03A61B6/10A61B5/00A61B8/00G01N21/17G01N23/04
CPCA61B5/0035A61B5/0059A61B6/032A61B6/107A61B6/5247A61B8/5261G01N21/1702G01N23/046G01N2021/1706G01N2201/06113G01N2223/03G01N2223/1016
Inventor 李长辉夏开业
Owner PEKING UNIV
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