Compound preparation for treating non-anaphylactoid purpura caused by spleen and kidney deficiency and preparation method

A technology for allergic purpura and compound preparations, applied in the directions of medical preparations containing active ingredients, pharmaceutical formulations, plant raw materials, etc., can solve the problems of lack of pertinence of drugs, side effects of drugs, and unsatisfactory effects, and improve bioavailability. , the dissolution rate is improved, the effect of helping the absorption

Active Publication Date: 2017-12-29
天津市善济宏兴科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many kinds of drugs used clinically to treat non-allergic purpura, there are many factors leading to non-allergic purpura, and there are many types of non-allergic purpura. Therefore, these drugs are not targeted, and th

Method used

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  • Compound preparation for treating non-anaphylactoid purpura caused by spleen and kidney deficiency and preparation method
  • Compound preparation for treating non-anaphylactoid purpura caused by spleen and kidney deficiency and preparation method
  • Compound preparation for treating non-anaphylactoid purpura caused by spleen and kidney deficiency and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0011] Example 1:

[0012] The compound preparation for the treatment of non-allergic purpura caused by deficiency of the spleen and kidney provided by the present embodiment is made from the following pharmaceutical raw materials in a weight ratio:

[0013]

[0014] The preparation method of the compound preparation for treating non-allergic purpura caused by deficiency of spleen and kidney is to weigh and mix the above-mentioned pharmaceutical raw materials according to the proportion, then add water to soak for 25 minutes, then decoct for 30 minutes, filter and remove the slag. The traditional Chinese medicine compound preparation for treating non-allergic purpura caused by deficiency of spleen and kidney can be prepared.

[0015] In addition, the traditional Chinese medicine compound preparation can be made into granules, tablets, capsules, syrups, oral liquids, pills and ointments with common pharmaceutical excipients.

Example Embodiment

[0016] Example 2:

[0017] The compound preparation for the treatment of non-allergic purpura caused by deficiency of the spleen and kidney provided by the present embodiment is made from the following pharmaceutical raw materials in a weight ratio:

[0018]

[0019] The preparation method is the same as in Example 1.

Example Embodiment

[0020] Example 3:

[0021] The compound preparation for the treatment of non-allergic purpura caused by deficiency of the spleen and kidney provided by the present embodiment is made from the following pharmaceutical raw materials in a weight ratio:

[0022]

[0023] The preparation method is the same as in Example 1.

[0024] The compound preparation for treating non-allergic purpura caused by deficiency of spleen and kidney provided by the invention is brown to tan; In order to verify the therapeutic effect of the traditional Chinese medicine compound preparation, the inventors used the above-mentioned traditional Chinese medicine compound preparation to carry out a systematic clinical observation on 420 patients suffering from spleen and kidney deficiency type non-allergic purpura, among which 102 patients aged 21-30, 31 -129 cases of 40 years old, 189 cases of 41-50 years old, 150ml each time, 3 times a day, 120 days as a course of treatment. After 1 course of treatme...

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Abstract

The invention relates to a compound preparation for treating non-anaphylactoid purpura caused by spleen and kidney deficiency and a preparation method. The preparation is prepared from the following pharmaceutical raw materials in percentage by weight: 18-48% of raw astragalus mongholicus, 6-15% of codonopsis pilosula, 9-24% of raw bighead atractylodes rhizome, 9-24% of poria cocos, 12-32% of prepared rehmannia root, 9-24% of Chinese yam, 6-15% of fructus corni, 12-32% of cuscuta chinensis, 4-10% of schisandra chinensis, 9-24% of hairyvein agrimonia herb, 6-15% of lithospermum and 9-24% of radix achyranthis bidentatae. According to the preparation, active ingredients in the pharmaceutical raw materials are extracted by a water cooking extraction method; the activity of the active ingredients are kept; the dissolubility of the active ingredients in the medicine can be improved greatly; the medicine absorption is facilitated, so that the bioavailability of the preparation can be improved. In addition, the medicine is a pure traditional Chinese medicine compound preparation, so that no toxic or side effect is generated after a patient takes the medicine for a long term, and the medicine is good in safety. In addition, the preparation method is simple in technology and convenient to operate.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a compound preparation and a preparation method for treating non-allergic purpura caused by spleen and kidney deficiency, which are made from traditional Chinese medicine. Background technique [0002] Nonallergic purpura is a hemorrhagic disease characterized by vascular abnormalities caused by various nonallergic etiologies and diseases. Clinically, it is mostly manifested as: skin purpura or ecchymosis, mucosal or visceral bleeding (rarely), Capillary fragility test can be positive, coagulation function, platelet count, platelet function and other tests are generally normal. There are many causes and diseases that cause non-allergic purpura, similar to the records of "muscle epistaxis" in traditional Chinese medicine. Although there are many kinds of drugs used clinically to treat non-allergic purpura, there are many factors leadin...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P7/04
CPCA61K36/076A61K36/21A61K36/284A61K36/30A61K36/344A61K36/39A61K36/40A61K36/43A61K36/481A61K36/57A61K36/73A61K36/79A61K36/804A61K36/8945A61K2236/331A61K2300/00
Inventor 马力王维蔚齐燕松
Owner 天津市善济宏兴科技发展有限公司
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