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Compound preparation for treating non-anaphylactoid purpura caused by spleen and kidney deficiency and preparation method

A technology for allergic purpura and compound preparations, applied in the directions of medical preparations containing active ingredients, pharmaceutical formulations, plant raw materials, etc., can solve the problems of lack of pertinence of drugs, side effects of drugs, and unsatisfactory effects, and improve bioavailability. , the dissolution rate is improved, the effect of helping the absorption

Active Publication Date: 2017-12-29
天津市善济宏兴科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many kinds of drugs used clinically to treat non-allergic purpura, there are many factors leading to non-allergic purpura, and there are many types of non-allergic purpura. Therefore, these drugs are not targeted, and the course of treatment is relatively short. Longer, and some drugs have certain side effects or allergic reactions, so after taking it, the effect is not ideal for the treatment of non-allergic purpura caused by spleen and kidney deficiency

Method used

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  • Compound preparation for treating non-anaphylactoid purpura caused by spleen and kidney deficiency and preparation method
  • Compound preparation for treating non-anaphylactoid purpura caused by spleen and kidney deficiency and preparation method
  • Compound preparation for treating non-anaphylactoid purpura caused by spleen and kidney deficiency and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The compound preparation for the treatment of non-allergic purpura caused by deficiency of the spleen and kidney provided in this example is made from the following pharmaceutical raw materials in terms of weight ratio:

[0013]

[0014] The preparation method of the compound preparation for treating non-allergic purpura caused by deficiency of the spleen and kidney is to weigh and mix the above-mentioned drug raw materials according to the proportion, then soak in water for 25 minutes, decoct for 30 minutes, filter and remove the residue The traditional Chinese medicine compound preparation for treating non-allergic purpura caused by spleen and kidney deficiency can be prepared.

[0015] In addition, the traditional Chinese medicine compound preparation can be prepared into granules, tablets, capsules, syrups, oral liquids, pills and ointments with commonly used pharmaceutical auxiliary materials.

Embodiment 2

[0017] The compound preparation for the treatment of non-allergic purpura caused by deficiency of the spleen and kidney provided in this example is made from the following pharmaceutical raw materials in terms of weight ratio:

[0018]

[0019] The preparation method is the same as in Example 1.

Embodiment 3

[0021] The compound preparation for the treatment of non-allergic purpura caused by deficiency of the spleen and kidney provided in this example is made from the following pharmaceutical raw materials in terms of weight ratio:

[0022]

[0023] The preparation method is the same as in Example 1.

[0024] The compound preparation for treating non-allergic purpura caused by deficiency of spleen and kidney provided by the invention is brown to brown in color; light in breath and slightly bitter in taste. In order to verify the therapeutic effect of this traditional Chinese medicine compound preparation, the present inventor has carried out systematic clinical observation on 420 patients suffering from non-allergic purpura of spleen-kidney deficiency type using the above-mentioned traditional Chinese medicine compound preparation, wherein 102 cases of patients aged 21-30, 31 - 129 cases aged 40, 189 cases aged 41-50, 150ml each time, 3 times a day, 120 days as a course of treat...

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Abstract

The invention relates to a compound preparation for treating non-anaphylactoid purpura caused by spleen and kidney deficiency and a preparation method. The preparation is prepared from the following pharmaceutical raw materials in percentage by weight: 18-48% of raw astragalus mongholicus, 6-15% of codonopsis pilosula, 9-24% of raw bighead atractylodes rhizome, 9-24% of poria cocos, 12-32% of prepared rehmannia root, 9-24% of Chinese yam, 6-15% of fructus corni, 12-32% of cuscuta chinensis, 4-10% of schisandra chinensis, 9-24% of hairyvein agrimonia herb, 6-15% of lithospermum and 9-24% of radix achyranthis bidentatae. According to the preparation, active ingredients in the pharmaceutical raw materials are extracted by a water cooking extraction method; the activity of the active ingredients are kept; the dissolubility of the active ingredients in the medicine can be improved greatly; the medicine absorption is facilitated, so that the bioavailability of the preparation can be improved. In addition, the medicine is a pure traditional Chinese medicine compound preparation, so that no toxic or side effect is generated after a patient takes the medicine for a long term, and the medicine is good in safety. In addition, the preparation method is simple in technology and convenient to operate.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a compound preparation and a preparation method for treating non-allergic purpura caused by spleen and kidney deficiency, which are made from traditional Chinese medicine. Background technique [0002] Nonallergic purpura is a hemorrhagic disease characterized by vascular abnormalities caused by various nonallergic etiologies and diseases. Clinically, it is mostly manifested as: skin purpura or ecchymosis, mucosal or visceral bleeding (rarely), Capillary fragility test can be positive, coagulation function, platelet count, platelet function and other tests are generally normal. There are many causes and diseases that cause non-allergic purpura, similar to the records of "muscle epistaxis" in traditional Chinese medicine. Although there are many kinds of drugs used clinically to treat non-allergic purpura, there are many factors leadin...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P7/04
CPCA61K36/076A61K36/21A61K36/284A61K36/30A61K36/344A61K36/39A61K36/40A61K36/43A61K36/481A61K36/57A61K36/73A61K36/79A61K36/804A61K36/8945A61K2236/331A61K2300/00
Inventor 马力王维蔚齐燕松
Owner 天津市善济宏兴科技发展有限公司
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