Traditional Chinese medicine for treating primary biliary cirrhosis and preparation method and application of traditional Chinese medicine

A technology for biliary cirrhosis and a composition, applied in the field of traditional Chinese medicine compositions, can solve the problems of no obvious benefit in the long-term survival rate of patients, inability to reduce the incidence of end-point events, poor patient compliance, etc., achieving no toxic side effects and convenient preparation. , the effect of simple formula

Inactive Publication Date: 2017-12-29
YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term studies have shown that these drugs have no significant benefit on the long-term survival rate of patients, cannot reduce the incidence of end-point events, and have obvious side effects and poor patient compliance

Method used

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  • Traditional Chinese medicine for treating primary biliary cirrhosis and preparation method and application of traditional Chinese medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Prescription: 1000 parts of capillary, 1500 parts of red peony, 600 parts of scorpion, 1500 parts of white fresh skin, 1800 parts of malt, 1000 parts of licorice;

[0034] Preparation:

[0035] (1) taking various raw materials according to the weight parts;

[0036] (2) Add 10 times the amount of water to the capillary, red peony root, scorpion, white fresh skin, malt and licorice weighed in step (1), decoct twice for 1.5 hours each time, combine the decoction, filter After passing, the filtrate is concentrated into a medicinal solution with a relative density of 1.10-1.20 (60°C);

[0037] (3) Add ethanol to the medicinal solution prepared in step (2) so that its alcohol content is 70%, stir fully, let it stand overnight, filter off the precipitate, and reclaim ethanol from the filtrate and concentrate to a relative density of 1.10 ~1.25(60℃) clear ointment, dried into dry powder;

[0038] (4) After adding the dry powder obtained in step (3) to microcrystalline cellu...

Embodiment 2

[0040] Prescription: 1200 parts of capillary, 1800 parts of red peony, 800 parts of scorpion, 1800 parts of white fresh skin, 2000 parts of malt, 1200 parts of licorice;

[0041] Preparation method: the preparation method is the same as in Example 1.

Embodiment 3

[0043] Recipe: 1500 parts of Yinchen, 2000 parts of red peony root, 800 parts of scorpion, 2000 parts of white fresh skin, 2500 parts of malt, 1500 parts of licorice

[0044] Preparation method:: the preparation method is the same as in Example 1.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine for treating primary biliary cirrhosis and a preparation method and application of the traditional Chinese medicine. The traditional Chinese medicine comprises the following raw materials in parts by weight: 500-1500 parts of oriental wormwood, 1000-2500 parts of roots of common peony, 500-1000 parts of scorpio, 1000-2000 parts of cortex dictamni, 1000-2500 parts of malt and 500-2000 parts of licorice roots. The traditional Chinese medicine disclosed by the invention has the main effects of clearing heat and removing toxin, soothing livers and dispersing gallbladder as well as activating blood and removing stasis, is capable of treating overlap syndromes of primary biliary cirrhosis caused by endoretention of damp heat, liver and gall stasis and Qi-stagnancy and blood stasis, and is simple in composition formula, outstanding in medicinal effect, free of toxic or side effect and convenient to prepare.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a traditional Chinese medicine composition for treating primary biliary cirrhosis, a preparation method and application thereof. Background technique [0002] Primary biliary cirrhosis (PBC) is an autoimmune liver disease of unknown etiology. Epidemiological surveys show that the number of PBC patients in China is on the rise, and the disease recurs and persists, which is an important cause of liver failure. At present, its intervention measures are mainly symptomatic and supportive treatment, and there is no radical cure. Various reports have shown that traditional Chinese medicine intervenes in PBC by means of syndrome differentiation and treatment, which has unique effects in improving liver function, symptom improvement, curative effect, and quality of life. [0003] For the treatment of PBC, the currently available drugs mainly...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8998A61P1/16A61K35/646
CPCA61K35/646A61K36/282A61K36/484A61K36/65A61K36/71A61K36/75A61K36/8998A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 浦仕彪徐福荣李维蛟张祎张希张丽娟
Owner YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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