Primers, probe and kit for detecting JCV (JC virus)
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- 湖北朗德医疗科技有限公司
- Publication Date
- 2018-01-16
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention relates to the field of biotechnology, in particular to a primer, a probe and a kit for detecting JC virus. Background technique
[0002] JC virus (JC virus, JCV) belongs to the Papovaviridae polyomavirus species human polyomavirus branch. In 1971, Pagett et al first isolated JC virus from the brain tissue of patients with progressive multifocal leukoencephalopathy (PML). JC virus exists widely in the human population, mainly lurking in tissues such as human kidneys. The infection of JC virus occurs in childhood, and it is in a state of continuous subclinical latent infection. In a healthy immune state, it can be asymptomatic for life, which belongs to asymptomatic infection. However, for AIDS patients or patients taking immunosuppressive drugs, it can cause PML and other series PML is a fatal demyelinating disease of the central nervous system. In recent years, studies have shown that JC virus is associated with the occurrence of a va...