Traditional Chinese medicine composition for treating neurodegenerative disease

A neurodegenerative and composition technology, applied in nervous system diseases, drug combinations, pharmaceutical formulations, etc., can solve problems such as difficulty in promoting research on the mechanism of action of traditional Chinese medicine compositions, inability to be widely used in clinical treatment, and lack of scientific evidence. , to achieve the effect of treating or preventing neurodegenerative diseases, reducing brain necrosis, and improving neuromotor function
CN107648482AInactive Publication Date: 2018-02-02GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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Patent Information

Authority / Receiving Office
CN Β· China
Current Assignee / Owner
GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
Publication Date
2018-02-02
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention discloses a traditional Chinese medicine composition for treating neurodegenerative diseases, which consists of the following traditional Chinese medicines in parts by weight: 2-60 parts of Smilax smilax, 1-30 parts of Gastrodia elata, and 1-30 parts of Angelica sinensis. The traditional Chinese medicine composition can obviously promote the proliferation of nerve cells and inhibit the death of nerve cells, and the combination of traditional Chinese medicines can play a synergistic effect compared with a single traditional Chinese medicine; it can be used in the Parkinson's disease model caused by MPTP in vitro. Reduce nerve cell death and restore the normality of mice, and be used in the Parkinson's disease model caused by rat 6-hydroxydopa, which can restore function and reduce brain necrosis area; the traditional Chinese medicine composition of the present invention can regenerate and replace dead Nerve area, to treat or prevent neurodegenerative diseases, reduce the activation of microglial cells in diseased tissue, and then protect nerve tissue, thereby reducing or alleviating, or even improving neuromotor function and improving a series of symptoms .
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Description

technical field

[0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating neurodegenerative diseases. Background technique

[0002] Neurodegenerative disease is a disease state in which cells and neurons of the brain and spinal cord are lost. The brain and spinal cord are composed of neurons. Neurons have different functions. Neurodegenerative diseases are caused by the loss of neurons or their myelin sheath. Aggravating over time to lead to functional impairment, neurodegenerative diseases are phenotypically divided into two groups: those affecting movement and those affecting memory and associated dementia.

[0003] Parkinson's Disease (PD) is a diagnostic concept commonly used by clinical neurologists, specifically referring to the following symptoms caused by various reasons (cerebrovascular disease, cerebral arteriosclerosis, infection, poisoning, trauma, drugs and genetic degener...

Claims

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