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Radix sophorae flavescentis tablet and preparation method thereof
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The technology of Sophora flavescens tablets and Sophora flavescens is applied in the directions of pharmaceutical formulations, medical preparations with inactive ingredients, medical preparations containing active ingredients, etc. , the effect of accelerating the dissolution
Inactive Publication Date: 2018-02-06
贵州浩诚药业有限公司
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Abstract
Description
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Problems solved by technology
[0004] The object of the present invention is to provide a Sophora flavescens tablet and its preparation method, which aims to improve the problem of poor efficacy of the existing flavescens tablets in the form of direct slices
Method used
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preparation example Construction
[0015] A preparation method of Sophora flavescens tablet, which comprises:
[0016] Take flavescens and decoct for 3-3.5 hours, filter to obtain the first filtrate, decoct the filter residue for 2-3 hours to obtain the second filtrate, combine the first filtrate and the second filtrate to concentrate to a relative density of 1.30-1.35 (50°C) extract.
[0017] The extract is mixed with flavescens powder passed through a 100-mesh sieve, dried and shaped.
[0018] Sophora flavescens, the name of traditional Chinese medicine. It is the dried root of the leguminous plant Sophora flavescens, excavated in spring and autumn, remove the root head and small branches, wash and dry, or slice and dry while fresh. Its bitter, cold. It has the functions of clearing away heat and dampness, killing parasites and diuresis.
[0019] In this example, by decocting Sophora flavescens twice, the matrine (C 15 h 24 N 2 O) and oxymatrine (C 15 h 24 N 2 〇 2 ) is dissolved as much as possible...
Embodiment 1
[0045] This embodiment provides a kind of Sophora flavescens tablet, and this Sophora flavescens tablet is mainly made by following preparation steps:
[0046] Take 149.94 kg of Sophora flavescens, add 8 times the amount of water to decoct twice, decoct for the first time for 3 hours and filter to get the first filtrate, decoct for the second time for 2 hours and filter to get the second filtrate, combine the first filtrate and the second Filtrate, the filtrate is concentrated into an extract with a relative density of 1.30 (50°C).
[0047] Take Sophora flavescens and crush it into fine powder, after passing through 100 meshes, weigh 30.06kg; mix the above-mentioned extract and Sophora flavescens powder, dry, pulverize, sieve, make granules, press into 180,000 pieces, coat with film, Instantly.
Embodiment 2
[0049] This embodiment provides a kind of Sophora flavescens tablet, and this Sophora flavescens tablet is mainly made by following preparation steps:
[0050] Take 144 kg of Sophora flavescens, add 8 times the amount of water to decoct twice, decoct for 3.5 hours for the first time, filter to get the first filtrate, decoct for the second time for 3 hours, filter to get the second filtrate, combine the first filtrate and the second filtrate , and the filtrate was concentrated into an extract with a relative density of 1.35 (50°C).
[0051] Take Sophora flavescens and crush it into fine powder, after passing through 100 meshes, weigh 36kg; mix the above-mentioned extract with Sophora flavescens powder, dry, pulverize, sieve, make granules, press into 180,000 pieces, and coat with film, that is have to.
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Abstract
The invention relates to the field of medicines, in particular to a radix sophorae flavescentis tablet and a preparation method thereof. The preparation method comprises the following steps of selecting radix sophorae flavescentis, decocting for 3 to 3.5h, and filtering, so as to obtain a first filtrate; decocting filter residues for 2 to 3h, so as to obtain a second filtrate; combining the firstfiltrate and the second filtrate, and concentrating into an extract with relative density of 1.30 to 1.35 (50 DEG C); mixing the extract and the radix sophorae flavescentis powder which is screened bya 100-mesh sieve, drying, and forming. The preparation method has the advantages that by decocting the radix sophorae flavescentis for two times, the matrine and oxidized matrine in the raw materialof radix sophorae flavescentis are furthest dissolved, and the contents of matrine and oxidized matrine in the extract are increased; after the extract and the radix sophorae flavescentis powder whichis screened by the 100-mesh sieve are mixed, the medicine effect of the radix sophorae flavescentis tablet is improved; by adopting an inner coat layer, the radix sophorae flavescentis tablet is prepared into larger or heavier tablets, so that the breaking of coat does not occur, or occurs at very small probability.
Description
technical field [0001] The invention relates to the field of medicines, in particular to a Sophora flavescens tablet and a preparation method thereof. Background technique [0002] Sophora flavescens, heat-clearing and damp-drying, insecticidal. It is used for various diseases such as dysentery, enteritis, and hot stranguria caused by damp heat accumulation. [0003] In the preparation process of the prior art, most of them are in the form of compressed tablets, or directly use the form of direct slicing of natural Sophora flavescens. The invention provides a new preparation method of Sophora flavescens slices. Contents of the invention [0004] The object of the present invention is to provide a Sophora flavescens tablet and a preparation method thereof, which aims to improve the problem of poor medicinal efficacy of the existing flavescens flavescens tablet in the form of direct slices. [0005] The invention provides a technical solution: [0006] A preparation meth...
Claims
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Application Information
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