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Dendrobium capsule and preparation process thereof

A preparation process and technology of dendrobium, applied in the field of medicine, can solve problems such as side effects and poor effect, and achieve the effects of simple raw materials, simple production process, and quick effect.

Inactive Publication Date: 2018-03-06
ANHUI YONSENT PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the medicine effect in the prior art is poor, also can bring certain side effect

Method used

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  • Dendrobium capsule and preparation process thereof
  • Dendrobium capsule and preparation process thereof

Examples

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Effect test

Embodiment 1

[0023] In an embodiment of the present invention, a dendrobium capsule comprises the following raw materials: 3 kg of dendrobium, 13 kg of broad-leaved top ten fruits, 10 kg of cubeb, 5 kg of citron, 17 kg of catechu, and 28 kg of ground loquat.

[0024] Pulverize the broad-leaved ten fruits and catechins, pass through a 100-mesh sieve, add 30% ethanol solution with 8 times the mass of the two, seal and heat-preserve at 75°C for 1 hour, and then ultrasonicate for 20 minutes with an ultrasonic power of 600W. The supernatant was collected by centrifugation to prepare mixture A; the centrifugation speed was 14000r / min, and the centrifugation time was 5min. Crush Dendrobium, pass through a 100-mesh sieve, add vinegar 2.5 times its mass, stir at 68°C for 60 minutes, then stir at 80°C until dry, then add deionized water 5 times its mass, ultrasonicate for 1 hour, and then Stir at 80°C until dry to obtain Dendrobium powder. Crush cubeb, citron, and ground loquat, pass through a 100-...

Embodiment 2

[0026] In an embodiment of the present invention, a dendrobium capsule comprises the following raw materials: 7 kg of dendrobium, 21 kg of broad-leaved top ten fruits, 20 kg of cubeb, 12 kg of citron, 25 kg of catechu, and 36 kg of loquat.

[0027] Pulverize the broad-leaved ten fruits and catechins, pass through a 150-mesh sieve, add 9 times the mass of the two in 30% ethanol solution, seal and heat-preserve at 78°C for 1.2h, and then ultrasonicate for 25min with an ultrasonic power of 600W. The supernatant was taken by centrifugation to prepare mixture A; the centrifugation speed was 14000r / min, and the centrifugation time was 10min. Crush Dendrobium, pass through a 150-mesh sieve, add vinegar 3 times its mass, stir at 70°C for 65 minutes, then stir at 80°C until dry, then add deionized water 6 times its mass, ultrasonicate for 1.2h, and then Stir at 80°C until dry to obtain Dendrobium powder. Crush cubeb, citron, and ground loquat, pass through a 150-mesh sieve, add 9 time...

Embodiment 3

[0029] In an embodiment of the present invention, a dendrobium capsule comprises the following raw materials: 4 kg of dendrobium, 15 kg of broad-leaved top ten fruits, 12 kg of cubeb, 7 kg of citron, 19 kg of catechu, and 30 kg of ground loquat.

[0030] Pulverize the broad-leaved ten fruits and catechu, pass through a 150-mesh sieve, add 8.5 times the mass of the two in 30% ethanol solution, seal and heat-preserve at 78°C for 1.2h, and then ultrasonicate for 25min with an ultrasonic power of 600W. The supernatant was taken by centrifugation to prepare mixture A; the centrifugation speed was 14000r / min, and the centrifugation time was 10min. Crush Dendrobium, pass through a 150-mesh sieve, add vinegar 2.8 times its mass, stir at 69°C for 65 minutes, then stir at 80°C until dry, then add deionized water 6 times its mass, ultrasonicate for 1.2h, and then Stir at 80°C until dry to obtain Dendrobium powder. Crush cubeb, citron, and ground loquat, pass through a 150-mesh sieve, ad...

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Abstract

The invention discloses a dendrobium capsule and a preparation process thereof. The dendrobium capsule is prepared from the following raw materials in parts by weight: 3-7 parts of dendrobium, 13-21 parts of mahonia bealei, 10-20 parts of piper cubeba, 5-12 parts of fructus citri, 17-25 parts of cutch and 28-36 parts of ficus tikoua. The preparation process comprises the following steps: grindingthe mahonia bealei and cutch, adding a 30% of ethanol solution to seal and maintain the temperature, and ultrasonically and centrifugally taking the supernatant to obtain a mixture A; grinding the dendrobium, adding table vinegar, and heating and stirring to be dry; adding deionized water for ultrasonic treatment, and stirring to be dry so as to obtain the dendrobium powder; grinding the piper cubeba, fructus citri and ficus tikoua, adding absolute ethyl alcohol for leaching twice, concentrating, freezing, performing vacuum drying, mixing with the mixture A and the dendrobium powder, performing ultrasonic treatment, drying, mixing with auxiliary materials, and filling in capsules, thereby obtaining the product. The dendrobium capsule disclosed by the invention has a significant effect on renal toxicity caused by chemoradiotherapy, does not have any toxic or side effect and is fast and short in efficacy and obvious in curative effects.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a dendrobium capsule and a preparation process thereof. Background technique [0002] Conventional methods used to treat tumor diseases have certain toxic effects on many organs, especially kidney toxicity, which has attracted more and more attention. Studies have shown that in the radiation treatment of tumor diseases, the radiation dose is 1000-2000 rads, and the kidneys will not produce persistent pathological abnormalities within 2-3 weeks; when the dose is 2300-2500 rads, it will be visible after 4-5 weeks Histopathological changes in the early stage of the kidney are mostly manifested as proliferation of glomerular endothelial cells and hyalinoid deposition in the inner and middle layers of arterioles, resulting in swelling of glomerular capillaries. Continuous radiation therapy can cause persistent damage to nephrons, leading to nephrotoxicity. Now there is a need for a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61K9/48A61P35/00A61P13/12A61P37/04
CPCA61K9/48A61K36/29A61K36/48A61K36/54A61K36/60A61K36/752A61K36/8984A61K2236/33A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 程玉柱夏运喜刘晓燕
Owner ANHUI YONSENT PHARMA
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