Transurethral optical-acoustic prostate imaging method and device based on ring array receiving

Abstract

The invention discloses a transurethral optical-acoustic prostate imaging method and device based on ring array receiving. The device comprises a pulse laser source excitation system, an optical fibercatheter scanning system, a ring array detector probe system, a signal collecting and conditioning system and a data processing system. Pulse laser is guided into the urethra through an optical fibercatheter, the pulse laser is irradiated to the portion to be tested of the prostate through rotating scanning, and therefore optical and acoustic signals are excited; the ring array detector is usedfor scanning and parallel receiving of full-angle optical and acoustic signals, the received optical and acoustic signals are amplified and filtered and converted into digital signals through a multi-channel signal collecting system, denoising is performed through the data processing system, and rebuilding and display are performed. The optical fiber catheter is used for transurethral internal full-angle and large-facula mechanical rotating excitation, the ring array detector performs electronic scanning and collecting, and prostate tissue full-range, high-contrast, high-resolution and rapid imaging can be achieved.

Description

technical field [0001] The invention belongs to the technical field of prostate imaging, and in particular relates to a transurethral photoacoustic prostate imaging method and device based on ring array reception. Background technique [0002] Photoacoustic imaging is a non-invasive imaging technology that combines optical imaging and ultrasound imaging. It has the characteristics of high contrast and high resolution of optical imaging and high penetration of ultrasound imaging. Photoacoustic imaging technology refers to that the light-absorbing medium irradiated by short-pulse laser heats up and expands rapidly after absorbing light energy. Since the irradiation time is much shorter than the heat conduction time inside the irradiated medium, instantaneous thermal expansion results in stressing out ultrasonic signals (called for the photoacoustic signal). Compared with pure optical imaging, the depth of photoacoustic imaging can reach centimeters; compared with pure ultraso...

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Problems solved by technology

The prostate is hidden and therefore difficult to diagnose

[0004] Transrectal ultrasound is the commonly used clinical prostate imaging method, but the glands on the side of the prostatic urethra are far away from the inner wall of the rectum, so the imaging resolution is low, which may affect the accuracy of clinical detection

Patent No. CN 105167808A proposes a transurethral prostate ultrasound detection method, diagnostic instrument and transducer, which uses a high-frequency micro-ultrasound probe to visualize the prostate through the urethra to obtain high-resolution images, but due to the contrast of ultrasound images Low, missed diagnosis and misdiagnosis still occur

Therefore, the high contrast of photoacoustic imaging is expected to make up for the shortcomings of ultrasonic imaging. Patent No. CN 106691391 A proposes a lateral scanning photoacoustic imaging method and device for the prostate. This invention irradiates the prostate tissue with light from the side through the urethra. , and the photoacoustic signal is received by the ultrasonic probe placed in the rectum, and the output light of the optical fiber is directly emitted by the mirror. Although a large spot irradiation is realized, the beam divergence angle is relatively large, so the penetration depth in the prostate tissue Low, and the ultrasound probe is placed in the rectum to receive, so it is impossible to realize the detection of the prostate body and the whole gland

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